VNU Journal of Science: Natural Sciences and Technology最新文献_第10页

A Green and Efficient NH4OAc-catalyzed Synthesis of 2-Hydroxy-3-(arylmethyl)(4-hydroxy-2-oxo-2,5-dihydrofuran-3-yl)-1,4-naphthoquinones 绿色高效nh4oac催化合成2-羟基-3-(芳基甲基)(4-羟基-2-氧-2,5-二氢呋喃-3-基)-1,4-萘醌

VNU Journal of Science: Natural Sciences and Technology Pub Date : 2022-06-23 DOI: 10.25073/2588-1140/vnunst.5353

Le Nhat Thuy Giang, D. T. T. Anh, Nguyen Ha Thanh, H. T. Phuong, Nguyen Tuan Anh, Nguyen Thi Quynh Giang, Vu Thi Thai Ha, N. Tuyen

引用次数: 1

Species composition of the subfamily Cetoniinae (Coleoptera: Scarabaeidae) from Phia Oac-Phia Den National Park, Cao Bang Province 曹邦省菲奥克-菲登国家公园蠓亚科的种类组成(鞘翅目:金龟科)

VNU Journal of Science: Natural Sciences and Technology Pub Date : 2022-06-10 DOI: 10.25073/2588-1140/vnunst.5264

P. Phu, Pham Thi Thao Nhi, Hoàng Vũ Trụ, Cao Thi Phi Nga

引用次数: 0

Evaluation the Ability to Isolate and Culture Stem Cells from Frozen Human Umbilical Cord Tissue 评价从冷冻人脐带组织中分离和培养干细胞的能力

VNU Journal of Science: Natural Sciences and Technology Pub Date : 2022-06-10 DOI: 10.25073/2588-1140/vnunst.5334

N. Nhung, D. T. Kien, N. Hiep, N. Hanh

{"title":"Evaluation the Ability to Isolate and Culture Stem Cells from Frozen Human Umbilical Cord Tissue","authors":"N. Nhung, D. T. Kien, N. Hiep, N. Hanh","doi":"10.25073/2588-1140/vnunst.5334","DOIUrl":"https://doi.org/10.25073/2588-1140/vnunst.5334","url":null,"abstract":"Umbilical cord-derived mesenchymal stem cells have been determined to be effective in cell therapy and regenerative medicine. Cell cryopreservation is widely used for long term preservation. However, cell cryopreservation is costly and labor consume. Therefore, cryopreservation of human umbilical cord (HUC) tissue has become an alternative solution to reduce the risks of disease and open up opportunities for later treatment for families in recent years. In this study, we evaluated the ability to isolate and the characteristic of mesenchymal stem cells (MSCs) derived from fresh and frozen human umbilical cord tissue. The results showed that the HUCMSCs were isolated successfully from both fresh and frozen HUC tissues. The expression of MSCs cell surface marker CD73, CD90, CD105 in group 1 were higher than those in group 2, CD73 (99,42 vs 95.2%); CD90 (99.74 vs 96.6%); CD105 (99.64 vs 96.15%), respectively. However, they are similar in morphology and osteogenic and adipose differentiated ability. The results of the study would be useful for stem cell research, cell therapy and regenerative medicine.","PeriodicalId":23524,"journal":{"name":"VNU Journal of Science: Natural Sciences and Technology","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91273233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Initial Usage of Fish Community to Assess Water Quality in Van Long Wetland Nature Reserve, Ninh Binh Province 宁平省万龙湿地自然保护区鱼类群落初始利用评价水质

VNU Journal of Science: Natural Sciences and Technology Pub Date : 2022-05-18 DOI: 10.25073/2588-1140/vnunst.5215

Tạ Thị Thu Thuỷ, D. T. Huong, Tran Duc Hau

{"title":"Initial Usage of Fish Community to Assess Water Quality in Van Long Wetland Nature Reserve, Ninh Binh Province","authors":"Tạ Thị Thu Thuỷ, D. T. Huong, Tran Duc Hau","doi":"10.25073/2588-1140/vnunst.5215","DOIUrl":"https://doi.org/10.25073/2588-1140/vnunst.5215","url":null,"abstract":"Van Long Wetland Nature Reserve is the 9th Ramsar of Vietnam, which has high biodiversity. To assess water quality in this area, the present study initially used the Shannon-Wiener Diversity Index (H') and IBI (Index of Biotic Integrity) of fish community collected in two field surveys in September 2019 and May 2020. A total of 33 fish species belonging to 18 families, 8 orders were determined. The H' index was 1.983 and IBI as 32 indicated that the water quality in the Van Long Wetland Nature Reserve was poor, probably influencing on aquatic organisms. In general, physical-chemical analysis methods revealed that most of the water parameters in the surface layer are good, but many parameters ranged from B1 to A2 levels, especially for TP (Phosphate calculated as P) being at poor level of pollution (B1-B2). Thus, results obtained from both bio-indices and physical-chemical analysis seem similar and indicate that the water in Van Long Wetland Nature Reserve was not completely clean. This finding will contribute to providing data for the conservation of biodiversity and ecotourism development in the reserved area.","PeriodicalId":23524,"journal":{"name":"VNU Journal of Science: Natural Sciences and Technology","volume":"64 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80823496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chemical Speciation, Risk Assessment and Pollution Level of Lead Metals in Road Dust of some Industry Zones and Urban Areas in Northern Vietnam 越南北部一些工业区和城市道路粉尘中铅金属的化学形态、风险评估及污染水平

VNU Journal of Science: Natural Sciences and Technology Pub Date : 2022-03-15 DOI: 10.25073/2588-1140/vnunst.5322

Thu Thuy Nguyen Thi

{"title":"Chemical Speciation, Risk Assessment and Pollution Level of Lead Metals in Road Dust of some Industry Zones and Urban Areas in Northern Vietnam","authors":"Thu Thuy Nguyen Thi","doi":"10.25073/2588-1140/vnunst.5322","DOIUrl":"https://doi.org/10.25073/2588-1140/vnunst.5322","url":null,"abstract":"This study analyzed the chemical speciation of Pb metal in road dust samples from six provinces in northern Vietnam. Samples were extracted according to Tesser's sequential extraction procedure. [22] and measured by the ICP/MS method, with the total recovery of Pb ranged from 90.9% to 107%. The analysis results showed that Pb existed mainly in the form of residual fraction F5 (38.6%) > organic fraction (29.0%), > Fe/Mn oxide fraction (19.2%) > exchange fraction, and carbonate fraction (5.00% and 8.32%, respectively). The pollution indices such as geological accumulation index (Igeo), individual contamination factor (ICF), and risk assessment index (RAC%) were utilized to evaluate pollution levels. The values of Igeo of Pb in samples ranged from 1.80 to 2.65, with a mean value of 2.24. The value of ICF varied from 0.60 to 2.87, with a mean value of 2.04. The values of RAC ranged from 4.47% to 23.2%, with a mean value of 13.3%. In general, the concentration of Pb in most of the studied samples in the six provinces were classified as low pollution and risk levels according to Igeo, ICF and RAC. However, in some provinces which have many industries producing electronic components, steel ore, and densely populated urban areas, the pollution level of Pb was from moderate to large, potentially affecting the environment of the studied areas.","PeriodicalId":23524,"journal":{"name":"VNU Journal of Science: Natural Sciences and Technology","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80792724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Second metabolite content and antioxidative, α-amylase inhibitory activity of Phellinus gilvus fruiting body extracts 茶树子实体提取物的代谢物含量及抗氧化、α-淀粉酶抑制活性

VNU Journal of Science: Natural Sciences and Technology Pub Date : 2022-03-15 DOI: 10.25073/2588-1140/vnunst.5171

Quang Dang Ngoc, H. Duong

{"title":"Second metabolite content and antioxidative, α-amylase inhibitory activity of Phellinus gilvus fruiting body extracts","authors":"Quang Dang Ngoc, H. Duong","doi":"10.25073/2588-1140/vnunst.5171","DOIUrl":"https://doi.org/10.25073/2588-1140/vnunst.5171","url":null,"abstract":"Fractions yielded from Phellinus gilvus fruiting bodies by liquid-liquid partition of methanol extract contained various bioactive compounds such as phenolics, flavonoids and terpenes. Butanol, water and ethyl acetate fractions had high content of total phenolics, 158.12 – 247.31 mg of gallic acid equivalents (GAE)/g and low content of flavonoids, 21.74 - 36.05 mg of quercetin equivalents (QE)/g, respectively. These values highly correlated with their antioxidant activity including 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging potential with IC50 values of 84.5 -108.44 μg/mL and reducing power. These fractions showed moderate α-amylase inhibitory activity with IC50 values of 4.77, 10.69 and 3.9 mg/mL respectively. The P. gilvus fractions exhibited very slight inhibitory activity on the growth of Gram-positive and Gram-negative bacterial strains at the concentration of 20 mg/mL. The results suggest the utility of butanol, water, and ethyl acetate fractions from fruiting bodies of P. gilvus collected in Vietnam for further characterization in order to apply for diabetes or anti-aging prevention.","PeriodicalId":23524,"journal":{"name":"VNU Journal of Science: Natural Sciences and Technology","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78326647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Đánh giá hàm lượng và rủi ro sinh thái của một số hợp chất clo hữu cơ khó phân hủy trong nước và trầm tích mặt sông Hồng đoạn chảy từ Hà Nội đến Nam Định 评估从河内到南方的一些难以溶于水中和沉淀物的有机氯化合物的数量和生态风险。

VNU Journal of Science: Natural Sciences and Technology Pub Date : 2022-03-15 DOI: 10.25073/2588-1140/vnunst.5170

Trịnh Thị Thắm

{"title":"Đánh giá hàm lượng và rủi ro sinh thái của một số hợp chất clo hữu cơ khó phân hủy trong nước và trầm tích mặt sông Hồng đoạn chảy từ Hà Nội đến Nam Định","authors":"Trịnh Thị Thắm","doi":"10.25073/2588-1140/vnunst.5170","DOIUrl":"https://doi.org/10.25073/2588-1140/vnunst.5170","url":null,"abstract":"Nghiên cứu này tập trung đánh giá mức độ phân bố hàm lượng của nhóm hóa chất bảo vệ thực vật họ clo hữu cơ (OCPs) và polyclhlorinated Biphenyls (PCBs) trong mẫu nước và trầm tích mặt tại sông Hồng đoạn chảy từ cuối địa phận thành phố Hà Nội đến thành phố Nam Định với chiều dài 85 km. Nhóm nghiên cứu đã tiến hành lấy 15 mẫu nước, 15 mẫu trầm tích mặt và tiến hành phân tích xác định hàm lượng OCPs, PCBs bằng sắc ký khí GC/ECD. Kết quả thu được hàm lượng tổng PCBs, HCHs, DDTs và tổng OCPs trong mẫu nước lần lượt dao động trong khoảng 0,013 ÷ 0, 033 µg/L; 0,601 ÷ 30,7 µg/L; 0,091 ÷ 2,73 µg/L và 1,27 ÷ 39,3 µg/L. Đồng thời, hàm lượng trung bình của các chất/nhóm chất trong trầm tích lần lượt là 23,3 µg/kg dw, 14,6 µg/kg dw, 1,16 µg/kg dw và 18,2 µg/kg dw. Kết quả đánh giá rủi ro bán định lượng đã chỉ ra mức độ rủi ro thấp đến trung bình của các chất/nhóm chất OCPs trong mẫu nước và mẫu trầm tích. Nghiên cứu là cơ sở khoa học để thực hiện các biện pháp kiểm soát ô nhiễm môi trường lưu vực sông","PeriodicalId":23524,"journal":{"name":"VNU Journal of Science: Natural Sciences and Technology","volume":"772 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86759545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Góp phần nghiên cứu tổng hợp một số N-(ω-azidoalkyl)isatin thế từ các isatin thế và không thế 有助于研究数字合成一个N -(ω-azidoalkyl)靛红这样,从他们的靛红的和没这个

VNU Journal of Science: Natural Sciences and Technology Pub Date : 2022-03-15 DOI: 10.25073/2588-1140/vnunst.5174

Nguyễn Đình Thành, Nguyễn Minh Trí, Vũ Ngọc Toán, Hoàng Mai Linh, Ngô Thị Ngọc Mai, Trần Thị Hải Yến, Ngô Thị Thủy, Nguyễn Thị Thuý Hường, Phạm Thị Thúy Vân, Nguyễn Thị Kim Giang, Đặng Thị Tuyết Anh

{"title":"Góp phần nghiên cứu tổng hợp một số N-(ω-azidoalkyl)isatin thế từ các isatin thế và không thế","authors":"Nguyễn Đình Thành, Nguyễn Minh Trí, Vũ Ngọc Toán, Hoàng Mai Linh, Ngô Thị Ngọc Mai, Trần Thị Hải Yến, Ngô Thị Thủy, Nguyễn Thị Thuý Hường, Phạm Thị Thúy Vân, Nguyễn Thị Kim Giang, Đặng Thị Tuyết Anh","doi":"10.25073/2588-1140/vnunst.5174","DOIUrl":"https://doi.org/10.25073/2588-1140/vnunst.5174","url":null,"abstract":"Tóm tắt: Các dẫn xuất azide của isatin là các chất đầu cần thiết cho phản ứng click để tạo ra dị vòng 1,2,3-triazole. Các dẫn xuất N-(ω-bromoalkyl)isatin cần cho chuyển hoá được tổng hợp từ phản ứng thế nucleophile của các isatin tương ứng với các dibromoalkane thích hợp. Một số N-(ω-azidoalkyl)isatin có chứa nhóm thế hoặc không thế ở vòng benzene đã được tổng hợp bằng phản ứng của các N-(ω-bromoalkyl)isatin tương ứng đã tổng hợp được với natri azide. Phản ứng được thực hiện trong DMF khan với sự có mặt của KI với vai trò chất xúc tiến. Hiệu suất sản phẩm đạt được 30−85%. \u0000Abstract: Azide derivatives of isatins were the needed initial materials for click chemistry in order to form 1,2,3-triazoles. N-(ω-Bromoalkyl)isatins were prepared by nucleophilic reaction of (un)substituted isatins with appropriate dibromoalkanes. Some ω-azidoalkylisatins were synthesized by reaction of corresponding ω-bromoalkylisatins with sodium azide. The reactions were performed in dry DMF as solvent in the presence of KI as promotive agent. Product yields achived 30−85%.","PeriodicalId":23524,"journal":{"name":"VNU Journal of Science: Natural Sciences and Technology","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89368060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Safety and Efficacy Evaluation of PRRS Attenuated Vaccine BG895 Strain in Experimental Pigs 猪PRRS减毒疫苗BG895对实验猪的安全性和有效性评价

VNU Journal of Science: Natural Sciences and Technology Pub Date : 2022-01-12 DOI: 10.25073/2588-1140/vnunst.5299

Bui Anh Thy, Nguyen Tang Truong, K. Phuc, N. T. Thu, N. V. Dũng, T. X. Hạnh, T. L. Thuoc

{"title":"The Safety and Efficacy Evaluation of PRRS Attenuated Vaccine BG895 Strain in Experimental Pigs","authors":"Bui Anh Thy, Nguyen Tang Truong, K. Phuc, N. T. Thu, N. V. Dũng, T. X. Hạnh, T. L. Thuoc","doi":"10.25073/2588-1140/vnunst.5299","DOIUrl":"https://doi.org/10.25073/2588-1140/vnunst.5299","url":null,"abstract":"From the PRRSV virulent strain BG8 isolated from a PRRSV-infected pig, using serial passage method in MARC-145 cell line, we have successfully obtained an attenuated strain in 95th passage, named as BG895, with high potential to be a vaccine candidate. In this study, we present the results of the safety and efficacy evaluation of BG895 against PRRSV in experimental pigs. Trial results of vaccine formula using strain BG895 have very high safety when inoculating 5 doses/animal and 10 doses/animal. Evaluation of immune response by ELISA method showed that, from 14 days post inoculation, anti-PRRSV antibodies were detected in the serum of all inoculated pigs in vaccine batches with the lowest S/P index of 1.50 ± 0.4 and the highest S/P was 2.36 ± 0.1 from 28 days post inoculation. The IPMA method showed that the antibody titer of the vaccine reached ≥ 1/160 in 100% of pigs from 21 days post inoculation andreached ≥ 1/640 in 100% of pigs from 28 days post inoculation, indicating that the vaccine was effective at protecting 100% of pigs from 28 days post inoculation. The protective effect of the vaccine was evaluated by the virulent challenge from 28 days post inoculation with 1 dose/animal compared with the control group. The results showed that compared with all pigs in the control group with typical clinical manifestations of Blue-ear disease, all inoculated pigs had normal body temperature and weight gain, besides, the S/P index increased from 1.65 ± 0.1 to the highest 2.99 ± 0.2; the average antibody titer was >1/2560, and virus wasnot detected in nasal fluid by real-time RT-PCR from 7 days post challenge. These experimental results confirmed the safety and efficacy of the attenuated PRRS vaccine based on BG895strain.","PeriodicalId":23524,"journal":{"name":"VNU Journal of Science: Natural Sciences and Technology","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88464770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preliminary Investigation of Microplastics in Sediments from Industrial Manufacturing Waste Sources 工业制造废弃物来源沉积物中微塑料的初步研究

VNU Journal of Science: Natural Sciences and Technology Pub Date : 2022-01-12 DOI: 10.25073/2588-1140/vnunst.5336

Doan Thi Hoang Oanh, D. T. Thủy, Nguyen Thi Giang Huong, H. T. Quỳnh, Phung Duc Hieu, Dang Minh Vu, Vu Thi Nguyet, L. Quynh, Bui Van Cuong, Bui Huyen Thuong

{"title":"Preliminary Investigation of Microplastics in Sediments from Industrial Manufacturing Waste Sources","authors":"Doan Thi Hoang Oanh, D. T. Thủy, Nguyen Thi Giang Huong, H. T. Quỳnh, Phung Duc Hieu, Dang Minh Vu, Vu Thi Nguyet, L. Quynh, Bui Van Cuong, Bui Huyen Thuong","doi":"10.25073/2588-1140/vnunst.5336","DOIUrl":"https://doi.org/10.25073/2588-1140/vnunst.5336","url":null,"abstract":"Microplastics (particles with a size of less than 5 mm) are a rising environmental problem. Microplastics can disseminate in the air and accumulate in sediments as well as in microorganisms and humans, due to their small size. Sediment is considered to be the major repository of microplastics, particularly those of the PE type. Microplastics in massive amounts accumulated in sediments, perhaps as a result of point sources or diffuse contamination. Microplastic contamination can spread from industrial production facilities, urban areas, agricultural areas, or the air. The current study was carried out to explore the occurrence of MPs in sediments at discharge sources by evaluating 27 sediment samples taken from 9 distinct waste sources from industrial activity locations to determine the amount of microplastic contamination in sediments at discharge sources. Microplastics with relatively high density were found in all sediment samples in this research, ranging from 2,900 to 238,200 particles/kg dw. The most prevalent microplastics detected in sediment samples at these sites were fibers and fragments, accounting for 59-94% and 6-41%, respectively. Fiber microplastics ranged in size from 1000 to 9,000 µm, whereas fragment microplastics ranged from 200,000 to 2,100,000 µm2. Microplastics with < 1000 µm and 1000-2000 µm sizes accounted for a significant portion of the total, reaching 21.05-37.84% and 39.74-61.17%, respectively. The hue of microplastic particles in sediment samples obtained was highly varied.","PeriodicalId":23524,"journal":{"name":"VNU Journal of Science: Natural Sciences and Technology","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86144980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1