Colorectal Oncology最新文献

{"title":"The role of conservative therapy in the treatment of complicated colorectal cancer","authors":"A. Ilkanich, V. Darvin, Ph. Sh. Aliev, S. Polozov","doi":"10.17650/2220-3478-2019-9-1-60-64","DOIUrl":"https://doi.org/10.17650/2220-3478-2019-9-1-60-64","url":null,"abstract":"","PeriodicalId":225735,"journal":{"name":"Colorectal Oncology","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122949802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bax protein as a prognostic marker in colorectal cancer: characteristics, role in apoptosis regulation, and correlation with disease prognosis (literature review)","authors":"A. Darenskaya, N. V. Dobrova, E. V. Stepanova","doi":"10.17650/2220-3478-2019-9-1-19-25","DOIUrl":"https://doi.org/10.17650/2220-3478-2019-9-1-19-25","url":null,"abstract":"","PeriodicalId":225735,"journal":{"name":"Colorectal Oncology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129809880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimal number of lymph nodes to be examined in stage II colon cancer","authors":"M. Fedyanin, A. Tryakin, A. Bulanov, S. Gordeev, D. Kuzmichev, Z. Mamedli, N. A. Kozlov, S. Tyulandin","doi":"10.17650/2220-3478-2019-9-1-42-50","DOIUrl":"https://doi.org/10.17650/2220-3478-2019-9-1-42-50","url":null,"abstract":"","PeriodicalId":225735,"journal":{"name":"Colorectal Oncology","volume":"255 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114936822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metastasectomy in patients with non-resectable metastatic colorectal cancer receiving chemotherapy and anti-EGFR antibodies: a prospective, non-randomized, multicenter, phase II study","authors":"M. Fedyanin, L. Vladimirova, N. A. Abramova, A. E. Storozhakova, I. Popova, N. Tikhanovskaya, E. A. Kalabanova, Е. Panina, A. Arzamastseva, E. Rybakov, L. Bolotina, T. V. Ustinova, А. А. Kachmazov, I. Pokataev, A. Tryakin, O. Sekhina, D. Chekini, Kheda Elsnukaeva, D. V. Podluzhniy, S. Tjulandin, O. Kit","doi":"10.17650/2220-3478-2019-9-1-65-72","DOIUrl":"https://doi.org/10.17650/2220-3478-2019-9-1-65-72","url":null,"abstract":"","PeriodicalId":225735,"journal":{"name":"Colorectal Oncology","volume":"03 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130496872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of sphincter-sparing surgeries in patients with rectal cancer: long-term experience of a specialized clinic","authors":"R. Tamrazov, Y. Barsukov, Z. Mamedli, V. Aliev, V. A. Ivanov","doi":"10.17650/2220-3478-2019-9-2-47-61","DOIUrl":"https://doi.org/10.17650/2220-3478-2019-9-2-47-61","url":null,"abstract":"Background. In this article, we analyze a 30-year experience of treating patients with rectal cancer and outcomes of sphincter-sparing surgeries (SSS) with manual coloanal anastomosis or mechanical colorectal anastomosis combined with various therapies. Objective: to optimize the indications for SSS considering tumor stage, treatment strategy, and overall performance status of a patient. Materials and methods . We analyzed short-term and long-term treatment outcomes of 1,440 patients with stage T2—3N0—2M0 rectal adenocarcinoma who underwent both surgery and various neoadjuvant therapies. A total of1,038 SSS were included into the final analysis. Four hundred and eighty-one patients underwent anterior rerections (AR) with mechanical anastomosis; 557patients underwent abdominoanal resections (AAR) with manual coloanal anastomosis; of them, 289 individuals had modified abdominoanal resection. Results. The overall frequency of postoperative complications after SSS was 24.3 %. The frequency of anastomosis leakage after AAR and AR was 9.5 % and 15 % respectively. Among patients with middle rectal cancer, there was no association between the type of surgery (AR or AAR) and the probability of relapse (p = 0.1823). In the subgroup with lower rectal cancer, patients that underwent abdominoperineal resection were more likely to have a relapse than those who underwent AAR (p = 0.042). The five-year overall survival rate reached 80 % in the group of SSS and 71 % in the group of abdominoperineal resection (p = 0.013). Year-on-year analysis of relapse-free survival after SSS demonstrated that it had significantly increased (from 63.5 % to 72.5%; p = 0.00077). The complex of rehabilitation measures in the early postoperative period after SSS ensures good functional effect in 51.5 % of cases. Conclusions. SSS planning should be considered from the standpoint of clinical experience as well as multivariate analysis of short-term and long-term treatment outcomes. Successful outcomes can be achieved by a combination of adequate surgical techniques and conservative rehabilitation even in patients with very low rectal cancer. Such combination ensures not only good cancer outcome, but also satisfactory functional results.","PeriodicalId":225735,"journal":{"name":"Colorectal Oncology","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130807135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term treatment outcomes in patients with low rectal cancer","authors":"A. Yudin, V. Kokhnyuk, G. I. Коlyadich","doi":"10.17650/2220-3478-2019-9-1-26-33","DOIUrl":"https://doi.org/10.17650/2220-3478-2019-9-1-26-33","url":null,"abstract":"","PeriodicalId":225735,"journal":{"name":"Colorectal Oncology","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132937738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic value of Bax expression in the primary colon tumor of patients with metastatic colorectal cancer receiving first-line treatment with a triple combination of irinotecan + oxaliplatin + long-term infusion of 5-fluorouracil","authors":"A. Darenskaya, N. V. Dobrova, E. V. Stepanova","doi":"10.17650/2220-3478-2019-9-1-51-59","DOIUrl":"https://doi.org/10.17650/2220-3478-2019-9-1-51-59","url":null,"abstract":"","PeriodicalId":225735,"journal":{"name":"Colorectal Oncology","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131441569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lipografting and stromal vascular fractions of adipose tissue in the treatment of patients with radiation-induced rectovaginal fistulas","authors":"Z. Teryushkova, V. Vasilyev, A. Vazhenin, S. Vasilyev, I. Eremin","doi":"10.17650/2220-3478-2019-9-1-34-41","DOIUrl":"https://doi.org/10.17650/2220-3478-2019-9-1-34-41","url":null,"abstract":"Objective : to analyze the efficacy of a newly developed method for the treatment of radiation-induced rectovaginal fistulas using autologous adipose tissue obtained by aspiration liposuction. Materials and methods . This retrospective study included 24 patients with radiation-induced rectovaginal fistulas that arose after chemoradiotherapy for malignant tumors of the female reproductive system. All patients underwent colostomy before treatment initiation. Study participants received 1 to 5 injections (mean number 3) of autologous adipose-derived regenerative cells. The main indication for the procedure was the presence of a fistula, diagnosed at least 6 months after the last course of radiation therapy. We evaluated time to fistula healing, results of elastometry, and presence of complications. Results. The mean total dose received by patients during their radiotherapy was 60 Gy; median time to initiation of fistula treatment was 15 months. Before the injection of adipose-derived regenerative cells, the mean fistula diameter was 2.50 + 0.46 cm, whereas after 3 months, it reduced to 1.35 + 0.47 cm and after 6 months, it was 1.12 + 0.47 cm. All patients had complete epithelialization of the defect. No cases of fistula recurrence were registered. Conclusion. We demonstrated high efficacy of a new reconstructive method for radiation-induced rectovaginal fistulas with autologous adipose tissue obtained by aspiration liposuction. Its effectiveness is confirmed by complete fistula closure and restoration of intestinal continuity in all study participants.","PeriodicalId":225735,"journal":{"name":"Colorectal Oncology","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126852695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical anatomy of the pelvis: role of parametrium","authors":"S. Nikogosyan, S. Gordeev, A. Tumanyan, A. Malikhov","doi":"10.17650/2220-3478-2019-9-1-11-18","DOIUrl":"https://doi.org/10.17650/2220-3478-2019-9-1-11-18","url":null,"abstract":"","PeriodicalId":225735,"journal":{"name":"Colorectal Oncology","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128827993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Colitis cystica profunda: literature review and case report","authors":"K. P. Sivokonev, G. P. Gens, O. Stukalova, V. Maslov, N. V. Gaydamaka, L. Korobkova","doi":"10.17650/2220-3478-2019-9-2-62-69","DOIUrl":"https://doi.org/10.17650/2220-3478-2019-9-2-62-69","url":null,"abstract":"Colitis cystica profunda is a rare nonmalignant disease, characterized by an inflammation of mucous coat of intestine and formation of submucous cysts. The clinical picture of this pathology and oncological diseases of colon and rectum is similar. It is very difficult and important to differentiate this disease from colorectal cancer to protect the patient from unjustified mutilating surgery. Nowadays either in Russian and foreign scientific literature there are single reports dedicated to this disease. In our opinion the publication of this clinical case and analysis of scientific literature devoted to this subject is currently important. In this article there is a short review of modern state of problem of diagnostics and treatment of colitis cystica profunda. Also there is an own rare clinical observation of a patient who was diagnosed with colitis cystica profunda.","PeriodicalId":225735,"journal":{"name":"Colorectal Oncology","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121734063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}