Scholars Academic Journal of Pharmacy最新文献

Ethics in Clinical Research: A Review 临床研究伦理：综述

Scholars Academic Journal of Pharmacy Pub Date : 2024-06-05 DOI: 10.36347/sajp.2024.v13i06.002

Ankur Yadav, Ankit Pandey, Sushil Kumar Tiwari

引用次数: 0

History, Classification and Application of Polymers: A Review 聚合物的历史、分类和应用：综述

Scholars Academic Journal of Pharmacy Pub Date : 2024-06-05 DOI: 10.36347/sajp.2024.v13i06.005

N. verma, Sudhanshu Dubey, Saurabh Singh, Sourav Sourav

引用次数: 0

A Review on Solid Dosage form: Tablet 固体制剂综述片剂

Scholars Academic Journal of Pharmacy Pub Date : 2024-06-05 DOI: 10.36347/sajp.2024.v13i06.003

N. verma, Uma Srivastava, Satya Prakash Singh, S. Yadav, Pragya Mishra

引用次数: 0

Phytochemical Profiling and their Pharmacological Activities of Traditional Plants of Euphorbiaceae Family: A Review 大戟科传统植物的植物化学成分分析及其药理活性：综述

Scholars Academic Journal of Pharmacy Pub Date : 2024-06-05 DOI: 10.36347/sajp.2024.v13i06.004

Shreya Maddhesiya, Neha Srivastava, Shiwani Jaiswal

{"title":"Phytochemical Profiling and their Pharmacological Activities of Traditional Plants of Euphorbiaceae Family: A Review","authors":"Shreya Maddhesiya, Neha Srivastava, Shiwani Jaiswal","doi":"10.36347/sajp.2024.v13i06.004","DOIUrl":"https://doi.org/10.36347/sajp.2024.v13i06.004","url":null,"abstract":"The Euphorbiaceae family has long been recognized for its diverse array of medicinal plants, containing bioactive compounds with significant pharmacological properties. This review aims to provide a comprehensive overview of the pharmacological potential of the Euphorbiaceae family. Through an extensive literature search, we identify and analyze studies highlighting the various pharmacological activities exhibited by members of this botanical family. These activities include antimicrobial, anti-inflammatory, anti-cancer, anti-diabetic, analgesic, and anti-oxidant effects, among others. Furthermore, we delve into the underlying mechanisms of action of these bioactive compounds, shedding light on their therapeutic relevance. Additionally, we discuss the traditional uses of Euphorbiaceae plants in indigenous systems of medicine, as well as their integration into modern pharmaceutical practices. Overall, this review underscores the significance of the Euphorbiaceae family in drug discovery and development, emphasizing the need for further research to fully harness its potential for the benefit of global health.","PeriodicalId":21439,"journal":{"name":"Scholars Academic Journal of Pharmacy","volume":"39 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141384594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Resealed Erythrocytes: A Comprehensive Review 再造红细胞：全面回顾

Scholars Academic Journal of Pharmacy Pub Date : 2024-06-05 DOI: 10.36347/sajp.2024.v13i06.008

N. verma, Swati Mishra, Shashi Srivastava, Praveen Kumar Rao, Satysaran Singh, Raghu nandan

{"title":"Resealed Erythrocytes: A Comprehensive Review","authors":"N. verma, Swati Mishra, Shashi Srivastava, Praveen Kumar Rao, Satysaran Singh, Raghu nandan","doi":"10.36347/sajp.2024.v13i06.008","DOIUrl":"https://doi.org/10.36347/sajp.2024.v13i06.008","url":null,"abstract":"Among the many carriers that are turned down for administering medications to various body nerves, cellular carriers must meet a number of requirements for clinical use, the most crucial of which is the carrier's biocompatibility with its degradation products. Leucocytes, platelets, erythrocytes, Nano erythrocytes, hepatocytes, and fibroblasts etc. have been proposed as cellular carrier structures. Among these, the erythrocytes have been the most explored and have found to own better potential in drug delivery. Bio-pharmaceuticals, intensely significant peptides and proteins, antigens, anticancer drug as well as vaccines, are among the freshly attentive pharmaceuticals for being transported using carrier erythrocytes. Vaccines, antigens, and anticancer drugs are among the pharmaceuticals that have recently been targeted for delivery via carrier erythrocytes. Red blood cells, or erythrocytes, have been studied in great detail because of their possible use as drug delivery vehicles. They are special and helpful carriers because of their biocompatibility, nonpathogenicity, nonimmunogenicity, and biodegradability. To prepare carrier erythrocytes, draw blood from the target organism and separate the erythrocytes from the plasma. Through a variety of techniques, the drug is entrapped within the broken cells, resulting in the erythrocytes being resealed and referred to as \"resealed erythrocytes\"—the carriers of the result. Many medications, such as aspirin, steroids, Resealed erythrocytes reduce the side effects of cancer drugs, which are numerous. The current review focuses on the isolation, drug loading techniques, evaluation techniques, and drug delivery applications of sealed erythrocytes.","PeriodicalId":21439,"journal":{"name":"Scholars Academic Journal of Pharmacy","volume":"27 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141382492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Herbal Treatment of Pneumonia (Treatment of Pneumonia from Medicinal Plants): A Review 肺炎的草药治疗（用药用植物治疗肺炎）：综述

Scholars Academic Journal of Pharmacy Pub Date : 2024-06-05 DOI: 10.36347/sajp.2024.v13i06.006

Sanjana Mishra, N. verma, Tarun Kumar

{"title":"Herbal Treatment of Pneumonia (Treatment of Pneumonia from Medicinal Plants): A Review","authors":"Sanjana Mishra, N. verma, Tarun Kumar","doi":"10.36347/sajp.2024.v13i06.006","DOIUrl":"https://doi.org/10.36347/sajp.2024.v13i06.006","url":null,"abstract":"Infectious diseases are caused by pathogenic microorganisms such as bacteria; fungus, influenza, and parasites. Illnesses have the ability to transmit between people through direct or indirect means. The world's second most common cause of death is infectious diseases. Roughly 25% of the medications humans require come from plants found in rainforests. Only a little amount of scientific research has been done on therapeutic plants. Due of bacteria's resistance to the antibiotics that are now in use, new antibacterial medicines have to be developed. In rural and underdeveloped parts of India, a variety of plants are commonly utilized as herbal medicines to cure infectious ailments. This chapter reviews the literature on the use of medicinal plants to treat illnesses like pneumonia and malaria. Traditional medicine is preferred primary health care system in many rural areas for variety of reasons, including its affordability and efficacy. The current study focused on existing medicinal plant literature, with ethnobotany, phytochemistry and pharmacology details being highlighted. All of examined plants showed potent action, supporting their conventional uses as well as their ability to cure common diseases. Curcuma longa L., Punica granatum L. and Justicia adhatoda L. were most widely used plant families for pneumonia therapy in research area (each with seven plants); of these, Curcumalonga L., Punica granatum L. and Justicia adhatoda L. had most inhibiting ability against Staphylococcusaureus and Streptococcus pneumoniae. Ascorbic acid, curcumin, vasicine, piperine, quercetin, myricetin and gallic acid have all been derived from these plants and are said to have antibacterial properties. Although Himalayan region has wide range of ethnomedicinal plants used to treat pneumonia, research on in-vivo activity, toxicology, and mechanism of action is minimal. As result, in order to produce novel antibacterial drugs from studied plant species, thorough study of these aspects","PeriodicalId":21439,"journal":{"name":"Scholars Academic Journal of Pharmacy","volume":"41 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141381815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Common Supplement Used in Inflammatory Bowel Disease 一种用于治疗炎症性肠病的常见补充剂

Scholars Academic Journal of Pharmacy Pub Date : 2024-06-05 DOI: 10.36347/sajp.2024.v13i06.007

Prashant Singh, N. verma, Raveesh Kharwar, Shail Kumari, Shivam Jaiswal, Satyam Bhardwaj

{"title":"A Common Supplement Used in Inflammatory Bowel Disease","authors":"Prashant Singh, N. verma, Raveesh Kharwar, Shail Kumari, Shivam Jaiswal, Satyam Bhardwaj","doi":"10.36347/sajp.2024.v13i06.007","DOIUrl":"https://doi.org/10.36347/sajp.2024.v13i06.007","url":null,"abstract":"Inflammatory bowel disease (IBD) is a chronic disease of the intestines. IBD, including Crohn's disease and ulcerative colitis, are characterized by a complex interplay of environmental, genetic, and immunological variables. Inflammatory bowel disease (IBD) is caused by the interplay of a person's immune system with precipitating environmental variables, which in people with a genetic predisposition causes an abnormally persistent inflammatory response. The pattern and severity of dietary deficits linked to IBD vary on the level, duration, and activity of the inflammation. However, there is little evidence that dietary changes can modify the course of IBD, and there are no evidence-based dietary recommendations for IBD patients. As a result, patients look to non-medical sources for nutritional advice, such as patient support groups and unreliable websites. The purpose of this review is to discover patient-specific dietary recommendations for IBD and to evaluate their nutritional value. We examine patient-specific dietary data for IBD from popular defined diets and structured internet searches. Dietary advice for specific patients focuses on.","PeriodicalId":21439,"journal":{"name":"Scholars Academic Journal of Pharmacy","volume":"312 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141386277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Colon Specific and Targeted Drug Delivery System (CDDS): A Review 结肠特异性和靶向给药系统 (CDDS)：综述

Scholars Academic Journal of Pharmacy Pub Date : 2024-06-04 DOI: 10.36347/sajp.2024.v13i06.001

Nimesh Agrawal, N. verma, Saumya Srivastava, Sanch Srivastava

引用次数: 0

Monitoring Adverse Effects and Efficacy Associated with Short-Term Mefloquine Chemoprophylaxis: Experience of the Moroccan Level II Hospital in the Democratic Republic of the Congo 监测与短期甲氟喹化学预防相关的不良反应和疗效：刚果民主共和国摩洛哥二级医院的经验

Scholars Academic Journal of Pharmacy Pub Date : 2024-03-23 DOI: 10.36347/sajp.2024.v13i03.003

Soufiane Ouelkabir, Chaimae Brahmi, Hamza Masca, Y. Tadlaoui

{"title":"Monitoring Adverse Effects and Efficacy Associated with Short-Term Mefloquine Chemoprophylaxis: Experience of the Moroccan Level II Hospital in the Democratic Republic of the Congo","authors":"Soufiane Ouelkabir, Chaimae Brahmi, Hamza Masca, Y. Tadlaoui","doi":"10.36347/sajp.2024.v13i03.003","DOIUrl":"https://doi.org/10.36347/sajp.2024.v13i03.003","url":null,"abstract":"Malaria is transmitted by a parasite carried by certain species of Anopheles mosquitoes. The much-debated mefloquine was discovered in the 1970s by U.S. Army researchers. It is widely used to prevent and treat malaria. Our aim is to evaluate the different types of adverse reactions reported by military personnel at the Moroccan hospital in the Democratic Republic of the Congo. This is a prospective, cross-sectional study lasting three months. It was carried out using a three-part questionnaire (patient identification, vector protection used, adverse events reported, and whether or not a malaria attack had occurred). 67 military personnel. The majority of soldiers were men (97.28%), with 95% aged between 26 and 45. 100% of soldiers used mosquito nets and repellents. During the first month of chemoprophylaxis, 30% of soldiers had adverse reactions (60% had nightmares, 30% had asthenia, and 10% had somnolence). From the second month onwards, 50% of soldiers had adverse reactions (65% nightmares, 40% asthenia, 20% memory disorders, 10% somnolence, 5% headaches, and 5% insomnia). Towards the end of the third month, 53% of servicemen experienced adverse reactions (65% nightmares, 40% asthenia, 20% memory disorders, 10% somnolence, 5% headaches, 5% insomnia, and 3% anxiety). During these three months, only one case suffered a malaria attack. Mefloquine is an antimalarial drug commonly used to prevent and treat malaria. It is important to note that chemoprophylaxis alone does not guarantee 100% protection against malaria. Additional measures must therefore be taken, such as wearing long, light clothing, using insecticide-impregnated mosquito nets, and using repellents.","PeriodicalId":21439,"journal":{"name":"Scholars Academic Journal of Pharmacy","volume":" 26","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140386618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CHF: A Disease Capturing Indians 慢性阻塞性肺病：俘获印第安人的疾病

Scholars Academic Journal of Pharmacy Pub Date : 2024-02-20 DOI: 10.36347/sajp.2024.v13i02.002

Vikas Sharma, Md Naushad ali, Md Osama Md Osama, Vatsala Agarwal, Syed Salman Ali, Anima Raut

{"title":"CHF: A Disease Capturing Indians","authors":"Vikas Sharma, Md Naushad ali, Md Osama Md Osama, Vatsala Agarwal, Syed Salman Ali, Anima Raut","doi":"10.36347/sajp.2024.v13i02.002","DOIUrl":"https://doi.org/10.36347/sajp.2024.v13i02.002","url":null,"abstract":"At 30% of all fatalities worldwide, cardiovascular diseases (CVDs) are the major cause of mortality. The WHO estimates that 17.9 million people die from CVDs annually and that number will rise to 22.2 million by 2030. As individuals age, the mortality rate rises. In terms of gender, women die from CVD at a greater rate (51%) than do men (42%). The intricate clinical illness known as congestive heart failure (CHF) is marked by an inefficient heartbeat, which compromises the body's blood flow. Any condition affecting blood ejection from the ventricles into the systemic circulation or ventricular filling might lead to CHF. Daucus carota, Nerium oleander, Amaranthus viridis, Ginkgo biloba, Terminalia arjuna, Picrorhiza kurroa, Salvia miltiorrhiza, Tinospora cordifolia, Mucuna pruriens, Hydrocotyle asiatica, Bombax ceiba, and Andrographis paniculate are a few medicinal plants that are well-known for treating cardiovascular disease. These plants include flavonoids, polyphenols, plant sterol, plant sulphur compounds, and terpenoids, which are active phytochemicals. Given the rising incidence of CVD, a number of physiologically active substances with established biological effects have been identified discovered in a variety of plants; nonetheless, proper CVD preventive and treatment strategies are still needed. To fully comprehend the mechanism and phytochemicals found in particular plants that cure CVD, more study is required.","PeriodicalId":21439,"journal":{"name":"Scholars Academic Journal of Pharmacy","volume":"165 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140445831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0