{"title":"Peripheral nervous system involvement in experimental tuberculosis.","authors":"H Mauss","doi":"10.1159/000162728","DOIUrl":"https://doi.org/10.1159/000162728","url":null,"abstract":"<p><p>Following intravenous injection of mycobacteria in the mouse the bacilli are regularly found in the peripheral nervous system after the 5th day. The peripheral nerves and autonomic ganglia are involved at the level of the perineural cells and the sheath of Schwann. When the organisms are of low virulence (BCG, Mycobacterium intracellulare) the development of the nodules is limited. In the case of a virulent strain (Ravenel) extensive granulomas are found but epitheloid cells, always found in other organs, are constantly absent. In animals previously immunized, the bacilli seem to implant themselves as in the controls, but multiply more slowly; the nodules are more infrequent and the lymphoid infiltration appears earlier with the multiplication of interstitial cells.</p>","PeriodicalId":19854,"journal":{"name":"Pathologia et microbiologia","volume":"42 2","pages":"103-9"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000162728","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12280619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Arterial lesions in polymyalgia arteritica.","authors":"G Oestberg","doi":"10.1159/000162817","DOIUrl":"https://doi.org/10.1159/000162817","url":null,"abstract":"","PeriodicalId":19854,"journal":{"name":"Pathologia et microbiologia","volume":"43 2-O","pages":"182-6"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000162817","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12405454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Luetic aortitis in El Salvador.","authors":"H Herrera","doi":"10.1159/000162810","DOIUrl":"https://doi.org/10.1159/000162810","url":null,"abstract":"","PeriodicalId":19854,"journal":{"name":"Pathologia et microbiologia","volume":"43 2-O","pages":"147-9"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000162810","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12412298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H Werner, H Kunstek-Santos, C Schockemöhle, M Gündürewa
{"title":"[Bacteroides and appendicitis (author's transl)].","authors":"H Werner, H Kunstek-Santos, C Schockemöhle, M Gündürewa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Bacteroides fragilis is frequently recovered from cases of appendicitis with perforation and from infections developing secondary to appendicitis. In order to assess the part played by B. fragilis in the aetiology of appendicitis, quantitative aerobic and anaerobic culture studies of the contents of 49 inflammated appendices were performed. Anaerobic gram-negative non-sporing rods were cultivated from 43 appendices in the range 10(3)-10(9)/g. A total of 1,473 isolates was differentiated by biochemical methods, and 1,374 cultures were found to belong to the saccharolytic species of the genus Bacteroides (B. fragilis, B. thetaiotaomicron, B. vulgatus, B. distasonis etc.). B fragilis was detected in 31 appendices; the species predominated in 18 samples. B theraiotamicron, recovered from 27 samples, was prevalent in 4 appendices. In one sample, B. fragilis and B. thetaiotaomicron outnumbered the other appendicular bacterial. B. vulgatus was cultivated from 12 appendices, but did once constitute the prevalent group. It has been previously shown that B. vulgatus (43% of intestinal isolates) and B. thetaiomicron predominate in the normal narge bowel flora. On the other hand, approximately 80% of pyrogenic Bacteroides strains belong to B. fragilis, B. thetaiotaomicron accounting for 19% and B. vulgatus being virtually absent. From these striking differences in species distribution the conclusion was drawn that B. fragilis possesses the highest virulence for man. Species distribution within the 1,374 appendicular isolates of saccharolytic Bacteroides (percentages of 62, 19 and 4.3 for B. fragilis, B. thetaiotaomicron, and B. vulgatus, respectively) was very similar to that encountered in clinical specimens. From the results obtained it becomes evident that pyrogenic Bacteroides, in particular B. fragilis, plays an important role in nearly 50% of cases of appendicitis.</p>","PeriodicalId":19854,"journal":{"name":"Pathologia et microbiologia","volume":"42 2","pages":"110-8"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12356038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Failure to induce autoimmune phenomena in mice by administration of highly purified C-type particles from NZB mice.","authors":"O L Schaap, E R De Groot, J J Van Loghem","doi":"10.1159/000162737","DOIUrl":"https://doi.org/10.1159/000162737","url":null,"abstract":"<p><p>Highly purified C-type particles from milk of NZB mice were ineffective in the transfer of Coombs positive hemolytic anemia and cryoglobulinemia to neonatal BALB/cHeA and NZC/B1 mice. Injection of neonatal NZB mice with these particles did not change the frequency or time of onset of these phenomena. Antinuclear antibodies were found in all injected animals in the same frequencies as in the control groups.</p>","PeriodicalId":19854,"journal":{"name":"Pathologia et microbiologia","volume":"42 3","pages":"171-87"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000162737","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11388858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[New methods for demonstration of antigens and antibodies (author's transl)].","authors":"U Krech","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>With the improvement of diagnostic procedure for the demonstration of antigens and antibodies it has been possible to increase the sensitivity and the specificity of antigen/antibody reactions, to introduce microtechniques and to apply a certain degree of automation and standardization, to allow a better interpretation of the results, and to cope with the ever increasing load of serological reactions.</p>","PeriodicalId":19854,"journal":{"name":"Pathologia et microbiologia","volume":"42 4","pages":"267-81"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12006665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Takayasu's truncoarteritis in Japan. A statistical observation of 76 autopsy cases.","authors":"T Nasu","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19854,"journal":{"name":"Pathologia et microbiologia","volume":"43 2-O","pages":"140-6"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11231099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Carcinoma and cirrhosis of the liver in A X C male rats with one kidney ingesting 0.025% N-2-fluorenyldiacetamide.","authors":"M D Reuber","doi":"10.1159/000162730","DOIUrl":"https://doi.org/10.1159/000162730","url":null,"abstract":"<p><p>The role of the kidneys in hepatic carcinogenesis was studies in inbred A X C strain male rats ingesting 0.025% N-2-fluorenyldiacetamide. The experimental groups consisted of male rats with both kidney intact and male rats that had the left kidney removed. The incidence of hepatic carcinomas and the number of rats with large carcinomas, multiple carcinomas, poorly differentiated and undifferentiated carcinomas, and metastases was greater in rats with a left nephrectomy. The incidence of cirrhosis was the same in animals in both groups; however, cirrhosis was more severe in degree in the rats with the left kidney removed. Some animals in the latter group also developed carcinosarcomas of the salivary glands. The animals with one kidney apparently were not able to excrete the active metabolites of N-2-fluorenyldiacetamide as readily as the animals with both kidneys intact. The metabolites were then returned to the liver and salivary gland.</p>","PeriodicalId":19854,"journal":{"name":"Pathologia et microbiologia","volume":"42 2","pages":"119-26"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000162730","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12356039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}