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Progress in the Study of Glycosylated Haemoglobin Variability Index in Relation to Chronic Complications of Diabetes Mellitus 糖化血红蛋白变异指数与糖尿病慢性并发症的关系研究进展
International Journal of Biology and Life Sciences Pub Date : 2023-07-12 DOI: 10.54097/ijbls.v3i2.9951
Ruihong Chen, Liangping Luo
{"title":"Progress in the Study of Glycosylated Haemoglobin Variability Index in Relation to Chronic Complications of Diabetes Mellitus","authors":"Ruihong Chen, Liangping Luo","doi":"10.54097/ijbls.v3i2.9951","DOIUrl":"https://doi.org/10.54097/ijbls.v3i2.9951","url":null,"abstract":"Diabetes mellitus (DM) is a common endocrine disease that can cause damage to tissues and organs throughout the body. Glycosylated haemoglobin (HbA1c) is considered to be the gold standard for assessing glycaemic control and treatment outcomes in patients with diabetes, but there is individual variability that affects the accurate interpretation of blood glucose. The glycosylated haemoglobin variability index (HGI) is a measure of individual variability in HbA1c and can be used in the management and treatment of patients with DM. In this paper, the relationship between HGI and chronic complications of DM is reviewed and discussed, with the aim of providing a more individualized and accurate reference for clinical management of blood glucose and risk assessment of chronic complications in DM patients, reducing and delaying the occurrence of chronic complications of diabetes and improving the quality of life of DM patients.","PeriodicalId":182292,"journal":{"name":"International Journal of Biology and Life Sciences","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121799550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thermo-tunable Injectable Thermosensitive Hydrogel and its Application as Protein Carriers 热可调注射型热敏水凝胶及其作为蛋白质载体的应用
International Journal of Biology and Life Sciences Pub Date : 2023-07-12 DOI: 10.54097/ijbls.v3i2.10088
Pengfei Xie, Lifang You, Yahao Ma, Tianyin Chen, Xiaoying Wang
{"title":"Thermo-tunable Injectable Thermosensitive Hydrogel and its Application as Protein Carriers","authors":"Pengfei Xie, Lifang You, Yahao Ma, Tianyin Chen, Xiaoying Wang","doi":"10.54097/ijbls.v3i2.10088","DOIUrl":"https://doi.org/10.54097/ijbls.v3i2.10088","url":null,"abstract":"It is known that polymer chemistries determine mechanical and physical properties of hydrogels and thus its drug delivery performance. In order to achieve desired drug release behavior, triblock copolyester PCT-PEG-PCT with proper hydrogel formulation has to be synthesized. This research has demonstrated a way to adjust hydrogel mechanical and gelation properties by simply physically mixing amphiphilic copolymers with different composition to achieve desired protein carriers. Tri-block copolymer poly (CL-co-TOSUO)-PEG-poly (CL-co-TOSUO), briefed as (PCT-PEG-PCT) with different composition have been successfully synthesized. These copolymers are thermosensitive and can form hydrogels in aqueous solution. Copolymers with higher percentage hydrophobic PCT blocks show higher mechanical stiffness and yet lower solubility. To reduce the crystallinity of the hydrophobic block and soften the hydrogel, the copolymer with long PCT blocks was physically mixed with ones with shorter PCT blocks. The polymer mixture demonstrated a moderated mechanical stiffness and desired solubility. The polymer mixture also achieved a gelation temperature at 37°C, which is desirable for drug delivery. Macromolecular drug, bovine serum albumin (BSA) was used as model drug for its release study. This protein drug was successfully loaded into the polymer mixture, and the drug release study shows the polymer mixture is able to extend a stable drug release for over 48 hours. This result confirms physical mixing of PCT-PET-PCT thermosensitive copolymers can tune gel properties and improve drug delivery performance without redesigning and synthesizing new polymers.","PeriodicalId":182292,"journal":{"name":"International Journal of Biology and Life Sciences","volume":"134 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123456400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Breast Cancer Prediction based on Support Vector Machine 基于支持向量机的乳腺癌预测
International Journal of Biology and Life Sciences Pub Date : 2023-07-12 DOI: 10.54097/ijbls.v3i2.10061
Tianci Liu, Xiangjun Li
{"title":"Breast Cancer Prediction based on Support Vector Machine","authors":"Tianci Liu, Xiangjun Li","doi":"10.54097/ijbls.v3i2.10061","DOIUrl":"https://doi.org/10.54097/ijbls.v3i2.10061","url":null,"abstract":"Breast cancer is the most common malignant tumor among women in the world, and its mortality rate ranks second. In this paper, the breath cancer Wisconsin (diagnostic) data set is used for prediction. First, exploratory data analysis was carried out, and 10 indicators related to breast cancer were selected as independent variables. Then, support vector machine (SVM) and logistic regression model were used as classifiers, and 75% of data sets were divided into training sets to build models. Finally, 25% of test sets were used as input models for prediction, and accuracy and recall were used as evaluation indicators to compare and analyze the advantages and disadvantages of the two algorithms. The results show that the accuracy of SVM is 16.2% higher than that of logistic regression, and the recall rate is 9.2% lower. The prediction application of SVM algorithm shows that SVM algorithm has low computational complexity and strong generalization ability. Therefore, support vector machine can be used to improve the diagnostic accuracy in the diagnosis of breast tumors.","PeriodicalId":182292,"journal":{"name":"International Journal of Biology and Life Sciences","volume":"428 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132367252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research on Wildlife Protection Strategy based on Fuzzy Evaluation Model 基于模糊评价模型的野生动物保护策略研究
International Journal of Biology and Life Sciences Pub Date : 2023-07-12 DOI: 10.54097/ijbls.v3i2.10077
Chuanqi Hua
{"title":"Research on Wildlife Protection Strategy based on Fuzzy Evaluation Model","authors":"Chuanqi Hua","doi":"10.54097/ijbls.v3i2.10077","DOIUrl":"https://doi.org/10.54097/ijbls.v3i2.10077","url":null,"abstract":"The number of wild animals is decreasing, and many species are on the verge of extinction. In order to put forward a wildlife protection policy that can achieve the goal of a win-win goal of environmental protection and economic development, this paper takes the Masai Mara Nature Reserve as an example. First, it analyzes the regional planning and wildlife population data of the Masai Mara Nature Reserve, and divides it into three major areas: Delansala, Narok and the tourist area. The characteristics of three different regions give specific policy strategies for each region to balance human activities and wildlife protection. Then establish a fuzzy comprehensive evaluation model, quantitatively score policy indicators, and get the best policy from the two dimensions of protecting wildlife and balancing human activities.","PeriodicalId":182292,"journal":{"name":"International Journal of Biology and Life Sciences","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132864210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intracortical Brain-machine Interface for Restoring Sensory Motor Function: Progress and Challenges 恢复感觉运动功能的皮质内脑机接口:进展与挑战
International Journal of Biology and Life Sciences Pub Date : 2023-06-26 DOI: 10.54097/ijbls.v3i2.10514
Xinyuan Wang
{"title":"Intracortical Brain-machine Interface for Restoring Sensory Motor Function: Progress and Challenges","authors":"Xinyuan Wang","doi":"10.54097/ijbls.v3i2.10514","DOIUrl":"https://doi.org/10.54097/ijbls.v3i2.10514","url":null,"abstract":"Limb loss or paralysis due to spinal cord injury has a devastating impact on quality of life. One way to restore the sensory and motor abilities lost by amputees and quadriplegics is to provide them with implants that interface directly with the central nervous system. Such Brain-machine interfaces could enable patients to exert active control over the electrical contractions of prosthetic limbs or paralysed muscles. The parallel interface can transmit sensory information about these motor outcomes back to the patient. Recent developments in algorithms for decoding motor intention from neuronal activity, using biomimetic and adaptation-based approaches and methods for delivering sensory feedback through electrical stimulation of neurons have shown promise for invasive interfaces with sensorimotor cortex, although significant challenges remain.","PeriodicalId":182292,"journal":{"name":"International Journal of Biology and Life Sciences","volume":"258 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116664752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Review: Fertility Stress, Hospital Depression and Anxiety, Resilience, and Hope among Infertile Women Patients 综述:不孕女性患者的生育压力、医院抑郁和焦虑、恢复力和希望
International Journal of Biology and Life Sciences Pub Date : 2023-06-26 DOI: 10.54097/ijbls.v3i2.10109
Guihong Song, Elna R. Lopez, Maria Jocelyn Natividad
{"title":"Review: Fertility Stress, Hospital Depression and Anxiety, Resilience, and Hope among Infertile Women Patients","authors":"Guihong Song, Elna R. Lopez, Maria Jocelyn Natividad","doi":"10.54097/ijbls.v3i2.10109","DOIUrl":"https://doi.org/10.54097/ijbls.v3i2.10109","url":null,"abstract":"Infertility, be named the third major disease endangering human health, has become a global concern in the 21st century point problem. The incidence of depressive and anxious symptoms in infertile women was 23.94% to 35.73%, and that of severe depression was 11.6%. They are under a lot of fertility pressure. This paper reviewed the relevant literature since 2015 to review the fertility stress, hospital depression and anxiety, social support, mental resilience and hope level status of infertile women, and discussed their relationships to provide evidence for intervention strategies.","PeriodicalId":182292,"journal":{"name":"International Journal of Biology and Life Sciences","volume":"181 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122788711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Summary of Research on Anti-aging from Genetic Perspective 从遗传学角度看抗衰老研究综述
International Journal of Biology and Life Sciences Pub Date : 2023-06-26 DOI: 10.54097/ijbls.v3i2.10526
Jie Gao, Eric Gao Zhou Quan
{"title":"A Summary of Research on Anti-aging from Genetic Perspective","authors":"Jie Gao, Eric Gao Zhou Quan","doi":"10.54097/ijbls.v3i2.10526","DOIUrl":"https://doi.org/10.54097/ijbls.v3i2.10526","url":null,"abstract":"As people age, the risk of diabetes, cardiovascular disease, cancer and neurodegenerative diseases increases, and globally, with the continuous improvement of living standards, people's life expectancy is also increasing, so how to enjoy a healthy old age, more and more attention, how to delay aging is a matter of concern. Anti-aging drugs were named one of the top ten breakthrough technologies in the world by MIT Technology Review in 2020. This paper elaborates on the progress of anti-aging research and summarizes it to provide reference for anti-aging theoretical research.","PeriodicalId":182292,"journal":{"name":"International Journal of Biology and Life Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129575488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Plant-based Diet on Type 2 Diabetes Risk: A Review of the Literature 植物性饮食对2型糖尿病风险的影响:文献综述
International Journal of Biology and Life Sciences Pub Date : 2023-06-26 DOI: 10.54097/ijbls.v3i2.10118
Ruixin Liu
{"title":"Effect of Plant-based Diet on Type 2 Diabetes Risk: A Review of the Literature","authors":"Ruixin Liu","doi":"10.54097/ijbls.v3i2.10118","DOIUrl":"https://doi.org/10.54097/ijbls.v3i2.10118","url":null,"abstract":"With the growth of global economy, people's dietary quality requirements and dietary quality level are also improving, but there are more bad diet and living habits. As a chronic metabolic disease, the incidence of diabetes has been increasing in recent years, which has seriously affected people's life quality and increased the economic burden of families. Adjust their own living habits, ensure a healthy diet and rest, in order to effectively reduce the incidence of diabetes. Plant-based diet consists of a variety of ingredients, including grains, nuts, vegetables and fruits, etc. Through scientific dietary nutrition combination and appropriate formulation, it can play a good role in helping the human body. Based on domestic and foreign research literature, this paper discusses the improvement of plant-based diet on type 2 diabetes risk, and puts forward suggestions on related diets and nutritional ways, in order to provide guidance for people's dietary habits.","PeriodicalId":182292,"journal":{"name":"International Journal of Biology and Life Sciences","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133258124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reflection on Standardized Training for Resident Physicians in Cardiology 关于心内科住院医师规范化培训的思考
International Journal of Biology and Life Sciences Pub Date : 2023-06-26 DOI: 10.54097/ijbls.v3i2.10525
Luchang Yin, Yongquan Liu, Xiuhong Dong
{"title":"Reflection on Standardized Training for Resident Physicians in Cardiology","authors":"Luchang Yin, Yongquan Liu, Xiuhong Dong","doi":"10.54097/ijbls.v3i2.10525","DOIUrl":"https://doi.org/10.54097/ijbls.v3i2.10525","url":null,"abstract":"The standardized training of residents is an important part of Graduate medical education for medical students after graduation. The Affiliated Hospital of Weifang Medical University, as a Teaching hospital approved as a training base, has accumulated rich clinical teaching experience. In the practice of residential training in the Department of Cardiology, we have found that by creating a positive learning atmosphere, improving teacher management mechanisms, establishing efficient training models, drawing on reasonable evaluation systems, taking into account the cultivation of scientific research and teaching abilities, and emphasizing humanistic quality education, it is possible to cultivate higher quality medical talents.","PeriodicalId":182292,"journal":{"name":"International Journal of Biology and Life Sciences","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130071128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute Traditional Chinese Medicine Fuzi Poisoning: A Case Report 急性中药附子中毒1例报告
International Journal of Biology and Life Sciences Pub Date : 2023-06-01 DOI: 10.54097/ijbls.v3i1.9631
Jingyang Sun, Juanjuan Guo
{"title":"Acute Traditional Chinese Medicine Fuzi Poisoning: A Case Report","authors":"Jingyang Sun, Juanjuan Guo","doi":"10.54097/ijbls.v3i1.9631","DOIUrl":"https://doi.org/10.54097/ijbls.v3i1.9631","url":null,"abstract":"Fuzi is lateral root of aconite crowfoot plants of aconite root of processed products, its medicinal sheen, sweet, hot, toxic, authority and by the kidney, spleen, for \"back to Yang inverse first to save medicine\", there are back to Yang Yang to save inverse, fire, cold analgesic effect, modern pharmacology study anti-inflammatory analgesic, cardiac, anti-aging and other functions, is the doctor of traditional Chinese medicine clinical commonly used drugs, often used in the treatment of cardiovascular diseases, diseases such as rheumatoid arthritis. According to different machining processing technology can be divided into salted aconite root, Heishun tablet, Baishun tablets, Light monkshood tablet, etc. Clinical use of Fuzi is often after processing and attenuation, but poisoning still occurs from time to time. A case of poisoning caused by taking Fuzi in our hospital is reported as follows.","PeriodicalId":182292,"journal":{"name":"International Journal of Biology and Life Sciences","volume":"125 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122896418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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