Journal of the Indonesian Chemical Society最新文献

Methods for Acrolein Detection: Recent Advances and Applications 丙烯醛的检测方法:最新进展及应用

Journal of the Indonesian Chemical Society Pub Date : 2020-08-31 DOI: 10.34311/jics.2020.03.2.73

A. Pradipta, Katsunori Tanaka

{"title":"Methods for Acrolein Detection: Recent Advances and Applications","authors":"A. Pradipta, Katsunori Tanaka","doi":"10.34311/jics.2020.03.2.73","DOIUrl":"https://doi.org/10.34311/jics.2020.03.2.73","url":null,"abstract":"Acrolein holds excellent potential as a critical biomarker in various oxidative stress-related diseases, and direct measurement of acrolein in biological systems is becoming essential to provide information for diagnosis and therapeutic purposes. In this review, we will discuss some available techniques for the detection of acrolein from biological samples. A conventional analytical method for the detection of acrolein by using high-performance liquid chromatography analysis after derivatization with 3-aminophenol is available. However, it is not suitable for high-throughput assay and inconvenient for measurement in clinical practice. On the other hand, we have recently discovered that phenyl azide can rapidly and selectively react with acrolein in a click manner to provide 4-formyl-1,2,3-triazoline through 1,3-dipolar cycloaddition. Moreover, we have successfully utilized this acrolein-azide click reaction as a simple and robust method for detecting and visualizing acrolein generated by live cells. Herein, we will describe our reaction-based acrolein sensor and its application to detect and visualize breast cancer tissues. We utilized the azide-acrolein click reaction-based method to discriminate breast cancer lesion from the normal breast gland, which resected from breast cancer patients. This method is the first example of an organic synthetic chemistry-based approach that can be used not only to visualize the cancer tissue but also to distinguish morphology of the resected tissue only within a few minutes. It has a potential clinical application for breast-conserving surgery. Furthermore, the ability to perform chemical reactions with cancer metabolites only at the desired cancer site is highly advantageous for cancer therapy.","PeriodicalId":166073,"journal":{"name":"Journal of the Indonesian Chemical Society","volume":"254 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115866218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

One-pot Facile Preparation of Amino-functionalized Silica Hybrid Monoliths for Mixed-mode Chromatography 一锅简易制备用于混合模式色谱的氨基功能化硅杂化单体

Journal of the Indonesian Chemical Society Pub Date : 2019-12-30 DOI: 10.34311/jics.2019.02.2.81

F. Furqani, L. Lim, T. Takeuchi

{"title":"One-pot Facile Preparation of Amino-functionalized Silica Hybrid Monoliths for Mixed-mode Chromatography","authors":"F. Furqani, L. Lim, T. Takeuchi","doi":"10.34311/jics.2019.02.2.81","DOIUrl":"https://doi.org/10.34311/jics.2019.02.2.81","url":null,"abstract":"Silica hybrid monolithic columns were prepared using two precursors, in which organo-functionalized trialkoxysilanes are mixed with tetraalkoxysilanes. In this study, several types of amino-functionalized silica hybrid monolithic columns were prepared via single-step “one-pot” approach, and the amount of silica precursors, porogens, as well as the reaction conditions were optimized. The preparation was carried out by mixing the silica precursors, i.e. tetraethoxysilane (TEOS) or tetramethoxysilane (TMOS) with amino precursors such as aminopropyltrimethoxysilane (APTES), aminoethylaminopropyl-trimethoxysilane (AEAPTMS), and phenylaminopropyltrimethoxysilane (PAPTMS) in a porogenic solution. The chromatographic performance of these hybrid monolithic columns was optimized by investigating several parameters through the separation of inorganic anions (IO3-, BrO3-, Br-, NO2-, NO3-, I-, SCN-) and some polar compounds (thymine, thymidine, adenosine, adenine, uridine). Results showed that the silica hybrid monolithic columns could be operated at higher flow-rate that favors rapid separation. The run-to-run repeatability of Si-APTES and Si-PAPTMS hybrid monolithic columns were satisfactory with relative standard deviations (n = 5) of less than 8% for all the analyte anions.","PeriodicalId":166073,"journal":{"name":"Journal of the Indonesian Chemical Society","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133590395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Predicting ADME and Molecular Docking Analysis of Andrographis paniculata and Strobilanthes crispus Chemical Constituents Againts Antidiabetic Molecular Targets 穿心莲与鹤耳花化学成分抗糖尿病分子靶点的ADME预测及分子对接分析

Journal of the Indonesian Chemical Society Pub Date : 2019-12-30 DOI: 10.34311/jics.2019.02.2.106

Julaiha, G. Widodo, R. Herowati

{"title":"Predicting ADME and Molecular Docking Analysis of Andrographis paniculata and Strobilanthes crispus Chemical Constituents Againts Antidiabetic Molecular Targets","authors":"Julaiha, G. Widodo, R. Herowati","doi":"10.34311/jics.2019.02.2.106","DOIUrl":"https://doi.org/10.34311/jics.2019.02.2.106","url":null,"abstract":"Andrographis paniculata and Strobilanthes crispus are two medicinal plants from Acanthaceae family, known to have antidiabetic activity. This study aimed to investigate the molecular interaction of A. paniculata and S. crispus phytochemical constituents with various macromolecular targets of antidiabetic agent through molecular docking. Nineteen A. paniculata and twenty S. crispus chemical constituents were docked to four macromolecular targets of antidiabetic agent by using AutoDock Vina in PyRx. The results revealed that compounds from A. paniculata that have the best binding affinity protein targets was 19-tripenhyl isoandrographolide to glucokinase (-10.4 kcal/mol), Dipeptidyl peptidase 4 (DPP4) (9.3 kcal/mol) and α-glucosidase (-8.8 kcal/mol), and andrographolactone to Protein Tyrosin Phosphatase1B (PTP1B) (-9.5 kcal/mol). Whereas compounds in the S. crispus derivatives that have the best binding affinity were stigmasterol to glucokinase (-9.9 kcal/mol), rutin to DPP4 (-9.7 kcal/mol), lupeol to α-glucosidase (-8.8 kcal/mol) and luteolin to PTP1B (-8.8 kcal/mol). The differences between the two plants were due to the differences in compounds in each of the plants as well as differences in target proteins. Other than that, profile of absorption, distribution, metabolism, and excretion (ADME) predictions are very important because they play a critical role in assessing the quality of potential clinical candidates for a new drug. Compounds with best binding energy that showed good ADME properties were andrographolactone, stigmasterol, lupeol and luteolin. Deoxyandrographolide was predicted to have the best ADME properties, however its affinity to target proteins was lower than native ligands.","PeriodicalId":166073,"journal":{"name":"Journal of the Indonesian Chemical Society","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128488538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A Perspective on Catalysis in the Immiscible Liquid-Liquid System 非混相液-液体系催化研究进展

Journal of the Indonesian Chemical Society Pub Date : 2019-12-30 DOI: 10.34311/jics.2019.02.2.66

Hadi Nur

引用次数: 2

Microfluidics Era in Chemistry Field: A Review 化学领域的微流体时代:综述

Journal of the Indonesian Chemical Society Pub Date : 2019-08-31 DOI: 10.34311/JICS.2019.02.1.7

Y. S. Kurniawan, A. C. Imawan, S. R. Rao, K. Ohto, W. Iwasaki, M. Miyazaki, Jumina

引用次数: 7

Application of Lecithin-templated Mesoporous Silica Microparticles for the Specific and Selective Removal of Phospholipids 卵磷脂模板化介孔二氧化硅微颗粒在磷脂的特异性和选择性去除中的应用

Journal of the Indonesian Chemical Society Pub Date : 2019-08-31 DOI: 10.34311/jics.2019.02.1.60

L. Lim, D. Marikah, T. Takeuchi

{"title":"Application of Lecithin-templated Mesoporous Silica Microparticles for the Specific and Selective Removal of Phospholipids","authors":"L. Lim, D. Marikah, T. Takeuchi","doi":"10.34311/jics.2019.02.1.60","DOIUrl":"https://doi.org/10.34311/jics.2019.02.1.60","url":null,"abstract":"Phospholipids are among the many components of algae bio oil, and they harbor the trans-esterification process by poisoning the catalyst, hence the need for they removal prior to this process is crucial. Mesoporous silica materials are feasible and viable candidates for the selective removal of phospholipids by tailoring their surface morphology using different surfactants (templates) for specific and selective adsorption. In this study, the adsorption of phospholipids using lecithin template mesoporous silica microparticles (Leci-MSM) was investigated. Comparative studies using cetyltriammoniumbromide mesoporous microparticles (CTAB-MSM) were also carried out. Both Leci-MSM and CTAB-MSM were synthesized via sol-gel process, packed into mini columns and used for column breakthrough adsorption studies. Scanning electron micrographs revealed a particle size of 5.0 µm for Leci-MSM and 2.95 µm for CTAB-MSM. Textural analysis by BET and BJH exhibited a surface area of 425 and 1210 m2/g for Leci-MSM and CTAB-MSM, respectively. A pore volume of 1.59 and 2.77 cc/g for Leci-MSM and CTAB-MSM, respectively, were also obtained. In addition, Leci-MSM revealed a column breakthrough volume of 28 mL at 41 min, while for the CTAB-MSM was 46 mL at 53 min. The actual adsorption capacity recorded by Leci-MSM was 11.34 mg/g and 8.71 mg/g for CTAB-MSM.","PeriodicalId":166073,"journal":{"name":"Journal of the Indonesian Chemical Society","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125467108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

On the Renewable Polymers from Agro-industrial Biomass: A Mini Review 农业-工业生物质可再生聚合物研究进展

Journal of the Indonesian Chemical Society Pub Date : 2019-08-31 DOI: 10.34311/jics.2019.02.1.24

R. A. Wahab, Adikwu Gowon Jacob, Nursyafiqah Elias

{"title":"On the Renewable Polymers from Agro-industrial Biomass: A Mini Review","authors":"R. A. Wahab, Adikwu Gowon Jacob, Nursyafiqah Elias","doi":"10.34311/jics.2019.02.1.24","DOIUrl":"https://doi.org/10.34311/jics.2019.02.1.24","url":null,"abstract":"Plant biomass is the most abundant natural resources on earth. However, current strategies for the utilization of agricultural biomass is far from efficient, thus environmental issues related to incompetent management of biomass prevail. Innovative handling of surplus biomass can yield several rewards, which includes renewability and sustainability of the commodity as feedstock for industrial and energy purposes. In fact, an array of different parts of a plant or agro-industrial biomass, for instance, shell, husks, wood, and leaves were successfully converted into advanced carbon materials, for use as absorbent, catalyst enzyme support, electrode, etc. In this review, an extensive literature survey related to areas of renewable sources of biopolymer in both the agricultural and industrial sectors were performed. Information on their industrial value and uses, the fundamentals of their extraction alongside the benefits and major drawbacks of their utilization, are also highlighted. We aim to show that the smart utilization of unwanted agro-industrial biomass encompasses a portion of a bigger scheme that intelligently uses biomass to complement current agricultural advancements that create smart crops and growing them using cleverly designed technology. The best part of this “Waste to Wealth” concept is that every part of the crop is fully utilized. However, a set of clear criteria must be in place to ensure a sustained momentum, so that the green approach of responsible biomass utilization will be fully embraced by nations worldwide.","PeriodicalId":166073,"journal":{"name":"Journal of the Indonesian Chemical Society","volume":"113 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124733307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Synthesis and Characterization of Activated Carbon from Sago Waste (Metroxylon sagu) with ZnCl2 Activation and HNO3 Modification 西米废活性炭的ZnCl2活化和HNO3改性合成及表征

Journal of the Indonesian Chemical Society Pub Date : 2019-08-31 DOI: 10.34311/jics.2019.02.1.48

Yanti Kiding Allo, Sudarmono, O. Togibasa

{"title":"Synthesis and Characterization of Activated Carbon from Sago Waste (Metroxylon sagu) with ZnCl2 Activation and HNO3 Modification","authors":"Yanti Kiding Allo, Sudarmono, O. Togibasa","doi":"10.34311/jics.2019.02.1.48","DOIUrl":"https://doi.org/10.34311/jics.2019.02.1.48","url":null,"abstract":"Previous researches have shown that activated carbon could be made from various raw materials which contain lignocellulose. The aims of this research were to synthesis and characterize the activated carbon obtained from lignocellulose contained in sago waste. The synthesis was conducted through multiple stages of dehydration, carbonization, silica extraction with NaOH, activation by ZnCl2 10%, and surface modification using HNO3 65%, successively. From X-ray fluorescence, it was confirmed that treatment with NaOH removed practically all silica content from the sample with only 1 wt% left. The X-ray diffraction patterns showed that the samples have amorphous structures before the modification and started to form exfoliated graphite crystals, as shown by the peaks at 2θ 30.27° and 35.10°. The significant result was obtained from the series of processes of carbonization, extraction, activation, and modification using 1.5 mL of HNO3 (CEA 1.5), which produced nanoporous particles with regular homogeneous shapes in the range of 200 nm in size as shown by scanning electron images. Finally, the infrared spectra from activated and modified samples confirmed that the oxygen-containing groups had increased.","PeriodicalId":166073,"journal":{"name":"Journal of the Indonesian Chemical Society","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130092196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Recent Advances in Injectable Hydrogels for Biomedical Applications 生物医学注射用水凝胶研究进展

Journal of the Indonesian Chemical Society Pub Date : 2019-08-31 DOI: 10.34311/jics.2019.02.1.1

Eko Adi Prasetyanto

引用次数: 2

Systematic Study of Calcination Temperature on Photocatalytic Activity of Luminescent Copper(I) Pyrazolate Complex/Titanium Oxide Composites 煅烧温度对发光吡甲酸铜配合物/氧化钛复合材料光催化活性的系统研究

Journal of the Indonesian Chemical Society Pub Date : 2019-08-31 DOI: 10.34311/jics.2019.02.1.54

Nurul Husna Sabran, L. Yuliati, S. Lee, Hendrik Oktendy Lintang

{"title":"Systematic Study of Calcination Temperature on Photocatalytic Activity of Luminescent Copper(I) Pyrazolate Complex/Titanium Oxide Composites","authors":"Nurul Husna Sabran, L. Yuliati, S. Lee, Hendrik Oktendy Lintang","doi":"10.34311/jics.2019.02.1.54","DOIUrl":"https://doi.org/10.34311/jics.2019.02.1.54","url":null,"abstract":"Columnar assembly of luminescent 3,5-dimethyl pyrazolate complexes/titanium oxide composites with different metal ions has shown significant improvement in its photocatalytic activity for the removal and degradation of 2, 4-dichlorophenoxyacetic acid (2,4-D). Since photocatalytic activity of semiconductor titanium oxide (TiO2) with an anatase phase can be improved by calcination temperature, we report the effect of heat treatments on the preparation of copper(I) 3,5-dimethyl pyrazolate complex/titanium oxide composite ([Cu3Pz3]/TiO2) for the removal and degradation of 2,4-D. Photocatalyst composites [Cu3Pz3]/TiO2 were successfully prepared using an impregnation method with different calcination temperature at 373, 473 and 573 K. Although, the activity of photocatalyst composites [Cu3Pz3]/TiO2 was significantly improved with increasing of calcination temperature on pure TiO2, it was slightly reduced with an increase of calcined temperature to 473 and 573 K. These results showed that [Cu3Pz3]/TiO2 was unstable at high temperature due to the decomposition of molecular structure of [Cu3Pz3] during the preparation of the photocatalyst. Hence, suitable calcination temperature is an important parameter to increase photocatalytic activity of photocatalyst composites [Cu3Pz3]/TiO2.","PeriodicalId":166073,"journal":{"name":"Journal of the Indonesian Chemical Society","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129519011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1