Journal of Exotic Pet Medicine最新文献

{"title":"Cardiorespiratory, analgesic and gastrointestinal effects of fentanyl and lidocaine in rabbits undergoing ovariohysterectomy","authors":"Taíse Fuchs ,&nbsp;Gabriel Aikawa Dusi ,&nbsp;André Saldanha ,&nbsp;Antonio Henrique Cereda da Silva ,&nbsp;Eloisa Muehlbauer ,&nbsp;Carolina Zaghi Cavalcante ,&nbsp;Cláudia Turra Pimpão","doi":"10.1053/j.jepm.2025.01.006","DOIUrl":"10.1053/j.jepm.2025.01.006","url":null,"abstract":"<div><h3>Background</h3><div>Despite high analgesic efficacy, full mu agonist opioids are used with caution in rabbits largely due to the potential for gastrointestinal side effects. Systemic lidocaine enhances intestinal motility and reduces nociception and inflammatory responses. This study aimed to evaluate the cardiorespiratory, analgesic, and gastrointestinal effects of continuous infusion of fentanyl and lidocaine in rabbits undergoing elective ovariohysterectomy (OVH).</div></div><div><h3>Methods</h3><div>Nineteen New Zealand White rabbits were assigned to 3 groups: lidocaine (LG), fentanyl (FG), and fentanyl+lidocaine (FLG). Drugs were administered as follows: L - 2 mg kg-1 IV and continuous rate infusion (CRI) at 6 mg kg-1 hour-1; F – 0.002 mg kg-1 IV and CRI at 0.01 mg kg-1 hour-1. Measured variables included cardiorespiratory parameters, expired fraction of isoflurane (FE'Iso), plasma glucose concentration, body weight, food and water consumption, fecal output and pain scores.</div></div><div><h3>Results</h3><div>Fentanyl reduced heart and respiratory rate in FG and FLG. Reduction in mean arterial pressure and a higher FE'Iso compared to baseline was observed in LG. There was no difference in pain scores between groups, but 2 animals from LG and one from FLG required analgesic rescue. FG and FLG had a reduction in body weight, water and food intake and fecal output, mostly on the first and second postoperative days.</div></div><div><h3>Conclusions and clinical relevance</h3><div>The CRI of fentanyl and/or lidocaine may contribute to analgesia in rabbits undergoing OVH, but lidocaine CRI should be included within a multimodal analgesia protocol. Fentanyl affects intestinal motility in rabbits and the addition of lidocaine does not appear to prevent the effect of the opioid on the gastrointestinal tract.</div></div>","PeriodicalId":15801,"journal":{"name":"Journal of Exotic Pet Medicine","volume":"52 ","pages":"Pages 62-70"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143094239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AEMV 1Q Newsletter 2025_print","authors":"","doi":"10.1053/S1557-5063(25)00018-7","DOIUrl":"10.1053/S1557-5063(25)00018-7","url":null,"abstract":"","PeriodicalId":15801,"journal":{"name":"Journal of Exotic Pet Medicine","volume":"52 ","pages":"Pages I-III"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143609804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinically relevant concentrations of pravastatin do not inhibit the in vitro growth of Nannizziopsis guarroi.","authors":"Christian N. Guerzon,&nbsp;Sophia Freda,&nbsp;Hugues Beaufrere,&nbsp;Krista Keller","doi":"10.1053/j.jepm.2024.12.002","DOIUrl":"10.1053/j.jepm.2024.12.002","url":null,"abstract":"","PeriodicalId":15801,"journal":{"name":"Journal of Exotic Pet Medicine","volume":"52 ","pages":"Pages 19-20"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143093898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Memoriam of Dr. Fredric L. Frye","authors":"","doi":"10.1053/j.jepm.2025.01.004","DOIUrl":"10.1053/j.jepm.2025.01.004","url":null,"abstract":"","PeriodicalId":15801,"journal":{"name":"Journal of Exotic Pet Medicine","volume":"52 ","pages":"Page 60"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143094235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EAAV_Newspage_2025_Issue_Mar","authors":"","doi":"10.1053/S1557-5063(25)00019-9","DOIUrl":"10.1053/S1557-5063(25)00019-9","url":null,"abstract":"","PeriodicalId":15801,"journal":{"name":"Journal of Exotic Pet Medicine","volume":"52 ","pages":"Pages IV-V"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143609805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multicentric B-cell lymphoma with otic involvement in 2 guinea pigs","authors":"Aaron J. Cooper ,&nbsp;Lorelei Clarke ,&nbsp;Christoph Mans","doi":"10.1053/j.jepm.2025.01.002","DOIUrl":"10.1053/j.jepm.2025.01.002","url":null,"abstract":"<div><h3>Objective</h3><div>To describe the diagnosis, treatment, and outcome of 2 guinea pigs with an atypical presentation of multicentric B-cell lymphoma with otic involvement.</div></div><div><h3>Animals</h3><div>Archived postmortem and medical records were searched for guinea pigs diagnosed with lymphoma affecting the middle and inner ears between 2016 and 2022. Two guinea pigs initially presented with otitis media/interna signs, one 4-year-old male and one 3.5-year-old female.</div></div><div><h3>Clinical Presentation</h3><div>Both guinea pigs presented for acute inappetence with either a head tilt or upper respiratory signs. Skull CT findings in both guinea pigs were suggestive of bilateral otitis media. Bloodwork and cytology for both guinea pigs were consistent with hemic neoplasia. Ultimately, humane euthanasia was elected for both animals.</div></div><div><h3>Results</h3><div>Microscopically, in both guinea pigs, there were neoplastic lymphocytic infiltrates in both inner and middle ears, invading adjacent bone and skeletal muscle. The neoplastic cells were positive for CD79a on immunohistochemistry. Both animals also had moderate, diffuse, chronic heterophilic otitis media with tympanic bone remodeling.</div></div><div><h3>Clinical relevance</h3><div>While clinical and computed tomographic findings suggested bacterial otitis media and interna, both animals had marked otic infiltration with neoplastic lymphocytes as part of multisystemic disease. Multicentric lymphoma with otic involvement should be considered a differential in guinea pigs with evidence of middle and inner ear disease.</div></div>","PeriodicalId":15801,"journal":{"name":"Journal of Exotic Pet Medicine","volume":"52 ","pages":"Pages 53-57"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143094233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Memoriam for PD Dr. Karina A. Mathes","authors":"","doi":"10.1053/j.jepm.2025.01.005","DOIUrl":"10.1053/j.jepm.2025.01.005","url":null,"abstract":"","PeriodicalId":15801,"journal":{"name":"Journal of Exotic Pet Medicine","volume":"52 ","pages":"Page 61"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143094236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Histopathological diagnosis of fibrosarcoma in a golden albino axolotl (Ambystoma mexicanum)","authors":"Natalia Alzate Henao ,&nbsp;Belfran Carbonell Medina ,&nbsp;Juliana Zapata Cardona","doi":"10.1053/j.jepm.2025.01.001","DOIUrl":"10.1053/j.jepm.2025.01.001","url":null,"abstract":"","PeriodicalId":15801,"journal":{"name":"Journal of Exotic Pet Medicine","volume":"52 ","pages":"Pages 41-42"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143092098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of a plasma retinol reference interval in eastern collared lizards (Crotaphytus collaris)","authors":"Brandon J. Louth ,&nbsp;Stephen A. Smith ,&nbsp;McAllister Council-Troche","doi":"10.1053/j.jepm.2024.10.002","DOIUrl":"10.1053/j.jepm.2024.10.002","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;The Eastern collared lizard (&lt;em&gt;Crotaphytus collaris&lt;/em&gt;) is a species of lizard native to the United States and Mexico and is growing in popularity in the exotic community around the world. There is minimal knowledge known on the analyte breakdown of this or closely related species. As this species becomes more popular in the exotic community more medical conditions are being identified that can be assisted in diagnosis with the establishment of ranges of the different essential analytes. Being an insectivorous lizard, this species may suffer from hypovitaminosis A. There has been a lack of antemortem diagnostics available for minimally invasive and appropriate diagnosis of this disease. Recent studies have been performed in other small insectivore species establishing plasma retinol reference intervals. Reference intervals for retinol have not been published or validated in collared lizards or any closely related species.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;Plasma, with a sample volume of only 50 µl, from forty clinically healthy captive bred Eastern collared lizards, twenty males and twenty females were analyzed using ultra-high-performance liquid chromatography with tandem mass spectrometry (UPLC-MS/MS) to determine plasma retinol concentrations.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;Using UPLC-MS/MS analysis, data was normally distributed and a reference interval for plasma retinol in the Eastern collared lizard was 1.57-3.07 µg/mL (0.237-0.464 µmol/L). A mean of 0.31µg/mL; with a lower limit 95% confidence interval being 1.34-1.80 µg/mL and upper limit of 2.84-3.30 µg/mL. Vitamin A (retinol) levels were significantly different when comparing a captive bred line called Blazing Blue (n = 4), with all other sampled captive bred localities. Including a closely related Aquaflames (n = 16), (Sky Blue) (n = 2), Western yellowhead (n = 5), Fancy Spotted (n = 4), Aquamarine (n = 3), and Lightning Yellow (n = 6); with the Blazing Blue morph being significantly lower using a t-Test comparison assuming equal variations. There was only 1 statistical variation seen in age groups between the 1-year-old and 6-year-old age groups with the 6-year-old age group being significantly lower than the 1-year-old age group. There was no variation based on sex.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusions and clinical relevance&lt;/h3&gt;&lt;div&gt;This study provides the first established plasma retinol range in a species in the suborder iguania. Values are valuable in assistance in diagnosing and treating hypovitaminosis A and to provide advice on dietary supplementation and dietary improvement for the collared lizards and possibly other related species as well. In addition, these values can be used to design and evaluate other studies for nutritional needs of this species. Limitations of this study include only a single season of collection, no same time comparison to liver values, some age groups were limited to only 1 individual, and the evaluation of only","PeriodicalId":15801,"journal":{"name":"Journal of Exotic Pet Medicine","volume":"52 ","pages":"Pages 4-8"},"PeriodicalIF":0.5,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142593578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of enrofloxacin administered subcutaneously or orally on the fecal microbiota of chinchillas (chinchilla lanigera)","authors":"Wei Wang ,&nbsp;Yuhong Wu ,&nbsp;Jing Li ,&nbsp;Xinyi Ma ,&nbsp;Luo Yang ,&nbsp;Lan Jiang ,&nbsp;Xinyi Lu ,&nbsp;Bo Liu","doi":"10.1053/j.jepm.2024.10.003","DOIUrl":"10.1053/j.jepm.2024.10.003","url":null,"abstract":"<div><h3>Background</h3><div>The gastrointestinal microbiota plays a vital role in the digestion of chinchillas. Antibiotics may exert negative effects on the gut microbiota, with relatively limited research conducted on chinchillas in this regard. This pilot study aimed to assess the effects of enrofloxacin via subcutaneous injection or oral administration on the fecal microbiota of chinchillas.</div></div><div><h3>Methods</h3><div>In a prospective, randomized, blinded, before and after experiment, nine healthy adult chinchillas were randomly assigned to one of three groups receiving no treatment (n = 3), enrofloxacin injection administered subcutaneously (SC) at 10 mg/kg (q12h, for 5 days, n = 3) and enrofloxacin tablet administered orally (PO) at 10 mg/kg (q12h, for 5 days, n = 3). Fecal samples collected from each group on Day 0, Day 6 and Day 14 underwent 16S rRNA sequencing and the results were statistically analyzed.</div></div><div><h3>Results</h3><div>The richness of the fecal microbiota was significantly decreased by Day 14 after administration of enrofloxacin in both SC and PO groups, but there was no significant difference between these two groups. Complete separations of bacterial composition were also observed in the PCoA and NMDS plots in PO group between Day 6 and Day 0, in SC group between Day 14 and Day 0. Significant changes in the relative abundance of dominant microbiota at both phylum and genus levels were noted on Day 14 in PO group. Specifically, there were significantly increased in the abundance of genus <em>Bacteroides</em> and <em>norank_f_Oscillospiraceae</em>. No significant changes in the dominant taxa were seen in SC group.</div></div><div><h3>Conclusions</h3><div>Enrofloxacin at 10 mg/kg SC or PO q12h for 5 days led to a significant decrease in the fecal microbiota diversity and alternations in its composition. Oral administration of enrofloxacin had a more significant effect on specific dominant taxa than subcutaneous injection, although the result needs to be interpreted cautiously as it is possible that the observed changes in microbiome could be due to the stress related to the administration process. Obvious clinical impact was not observed in any of the groups during the study. Therefore, administration of enrofloxacin at 10mg/kg SC and PO q12h for 5 days were both considered clinically safe.</div></div>","PeriodicalId":15801,"journal":{"name":"Journal of Exotic Pet Medicine","volume":"52 ","pages":"Pages 9-16"},"PeriodicalIF":0.5,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142660672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}