Journal of endometriosis and pelvic pain disorders最新文献_第5页

Validity and reliability test of ENDOCARE questionnaire adoption on endometriosis patients in Indonesia 印度尼西亚子宫内膜异位症患者采用ENDOCARE问卷的有效性和可靠性检验

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Journal of endometriosis and pelvic pain disorders Pub Date : 2022-04-24 DOI: 10.1177/22840265221093259

A. K. Harzif, Agatha Pradana, R. Muharam, M. Maidarti, G. Pratama, K. Sumapraja, Fistyanisa Elya Charilda, Azizah Fitriayu Andyra

{"title":"Validity and reliability test of ENDOCARE questionnaire adoption on endometriosis patients in Indonesia","authors":"A. K. Harzif, Agatha Pradana, R. Muharam, M. Maidarti, G. Pratama, K. Sumapraja, Fistyanisa Elya Charilda, Azizah Fitriayu Andyra","doi":"10.1177/22840265221093259","DOIUrl":"https://doi.org/10.1177/22840265221093259","url":null,"abstract":"Background: Endometriosis is a health problem that causes various biological, psychological, and social problems. Patient-centered care is the best standard of care in endometriosis cases. ENDOCARE is an questionnaire assessing all dimensions of patient-centered endometriosis care. However, there has been no adoption of this questionnaire in Indonesia. Aim: To determine the validity and reliability of the Indonesian version of the ENDOCARE questionnaire. Method: This study is a cross-sectional study conducted on patients with endometriosis on Dr. Cipto Mangunkusumo, Jakarta, Indonesia from July 2020 to December 2020. Patients with communication problems were excluded from the study. The English version of the ENDOCARE questionnaire was translated into Indonesian and back into English by sworn translators and specialists in obstetrics and gynecology. Analysis of the validity and reliability of ENDOCARE was carried out. Result: There were 108 respondents who were included in the study. Percentage of negative experience (PNP), mean important score (MIS), and patient-centered care (PCS) score were analyzed. Validity and reliability tests were performed. There were 38 questions covering 10 dimensions in the Indonesian version of the ENDOCARE questionnaire Conclusion: The Indonesian version of the ENDOCARE questionnaire is a valid and reliable questionnaire in assessing patient-centered care of endometriosis.","PeriodicalId":15725,"journal":{"name":"Journal of endometriosis and pelvic pain disorders","volume":"14 1","pages":"123 - 131"},"PeriodicalIF":0.5,"publicationDate":"2022-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47498766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dysmenorrhea and associated symptoms in Ethiopia: A systematic review and meta-analysis 埃塞俄比亚痛经及相关症状:一项系统回顾和荟萃分析

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Journal of endometriosis and pelvic pain disorders Pub Date : 2022-04-18 DOI: 10.1177/22840265221080107

Getnet Gedefaw, Adam Wondmieneh, Addisu Getie, Fikadu Waltengus, Asmamaw Demis, C. Wang

{"title":"Dysmenorrhea and associated symptoms in Ethiopia: A systematic review and meta-analysis","authors":"Getnet Gedefaw, Adam Wondmieneh, Addisu Getie, Fikadu Waltengus, Asmamaw Demis, C. Wang","doi":"10.1177/22840265221080107","DOIUrl":"https://doi.org/10.1177/22840265221080107","url":null,"abstract":"Introduction: Dysmenorrhea is the most common gynecologic compliant and reproductive health problem among adolescents, young, and reproductive age group. Dysmenorrhea has psychological, physical, and behavioral impact on adolescent girls in different regions. Objective: This systematic review and meta-analysis aimed to assess the overall prevalence of dysmenorrhea, its pain intensity and associated symptoms in Ethiopia and compare with other countries. Methods: Literatures from PubMed, MEDLINE, EMABSE, CINHAL, SCOPUS, Hinari, Africa journals, and Google scholar were retrieved. Eligible cross-sectional studies were included for meta-analysis. I2 statistics was calculated to check heterogeneity. Subgroup analysis based on outcome of interest was performed. Sensitivity analysis was undertaken to examine the level of heterogeneity. Results: The prevalence of overall and primary dysmenorrhea in Ethiopia was 72% (95%CI 68–77) and 72.27% (95%CI 69.8–75.33) respectively. Back pain 56.62% (95%CI 46.68–66.57) and fatigue 51.51% (95%CI 40.08–62.94) were more common than headache 29.15% (95%CI 18.16–40.14) whereas moderate pain 41.03% (95%CI 33.98–48.07) was more common than mild 31.83% (95%CI 21.61–42.05) and severe pain intensity 21.57% (95%CI 14.24–28.89). The prevalence between small and large samples, Northern and South/West Ethiopia, and school girls and university students were nearly similar. Positive family history (OR = 4.05; 95%CI 3.15–5.20), early menarche (OR = 2.91; 95%CI 2.00–4.24) and irregular monthly menstrual cycle (OR = 1.87, 95%CI 1.23–2.84) were the predictors of dysmenorrhea. Conclusion: Compared with other countries, the prevalence of dysmenorrhea in Ethiopia is moderate, presenting as mainly back pain and fatigue with moderate pain intensity. Positive family history, early menarche, and irregular menstrual cycle are the positive contributing factors.","PeriodicalId":15725,"journal":{"name":"Journal of endometriosis and pelvic pain disorders","volume":"14 1","pages":"106 - 119"},"PeriodicalIF":0.5,"publicationDate":"2022-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48623582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Measuring intraobserver and intermethod reliability of endometriotic cyst volumes: A comparison between MRI and 3D transvaginal ultrasound in endometriosis 测量子宫内膜异位症囊肿体积的观察内和方法间可靠性:子宫内膜异位症MRI与三维经阴道超声的比较

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Journal of endometriosis and pelvic pain disorders Pub Date : 2022-03-31 DOI: 10.1177/22840265221084928

J. Bergwerff, A. Schreurs, M. C. Lier, J. V. van Waesberghe, L. V. D. van der Houwen, V. Mijatovic

{"title":"Measuring intraobserver and intermethod reliability of endometriotic cyst volumes: A comparison between MRI and 3D transvaginal ultrasound in endometriosis","authors":"J. Bergwerff, A. Schreurs, M. C. Lier, J. V. van Waesberghe, L. V. D. van der Houwen, V. Mijatovic","doi":"10.1177/22840265221084928","DOIUrl":"https://doi.org/10.1177/22840265221084928","url":null,"abstract":"Objectives: To identify the intraobserver and intermethod reliability of three-dimensional transvaginal ultrasound (3D-TVUS) using the software VOCAL and XI VOCAL compared with magnetic resonance imaging (MRI) for volumetric measurement of ovarian endometrioma. Methods: The intermethod and intraobserver reliability of endometrioma volumes were assessed in 16 women diagnosed with endometriosis through laparoscopy with histologic confirmation and presenting with uni- or bilateral endometriomas. In total, volumes of 23 endometriomas were assessed with two-dimensional and three-dimensional transvaginal ultrasound and 6 mm magnetic resonance imaging. Examinations took place at two moments in one menstrual cycle: day 2–4 (T0) and day 20–22 (T1). Results: The intraclass correlation for intraobserver reliability is good to very good for all three techniques ranging from the lowest value of 0.953 to the highest of 1.000. MRI has the most narrow limits of agreement (−3.93 to 4.53), followed by XI VOCAL (−5.16 to 5.65) while VOCAL has the widest limits of agreement (−10.22 to 11.39). Intraclass correlations are poor in the comparison of XI VOCAL to MRI, moderate between VOCAL and XI VOCAL, and good for the comparison between VOCAL and MRI. Limits of agreement vary per technique. When comparing 3D imaging techniques with 2D TVUS, XI VOCAL versus 2D TVUS provide the smallest limits of agreement. Conclusions: MRI and XI VOCAL provide the best intraobserver reliability. The different imaging techniques are not interchangeable. As TVUS is a more readily available and cost-efficient imaging technique the usage of XI VOCAL is advised.","PeriodicalId":15725,"journal":{"name":"Journal of endometriosis and pelvic pain disorders","volume":"14 1","pages":"80 - 86"},"PeriodicalIF":0.5,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46855940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Subjective theories of illness in fibroid and endometriosis patients: Similarities, differences, and influencing factors 纤维瘤和子宫内膜异位症患者的主观疾病理论：相似性、差异性和影响因素

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Journal of endometriosis and pelvic pain disorders Pub Date : 2022-03-13 DOI: 10.1177/22840265211073017

Friederike Münch, A. Ebert, S. Mechsner, R. Richter, M. David

{"title":"Subjective theories of illness in fibroid and endometriosis patients: Similarities, differences, and influencing factors","authors":"Friederike Münch, A. Ebert, S. Mechsner, R. Richter, M. David","doi":"10.1177/22840265211073017","DOIUrl":"https://doi.org/10.1177/22840265211073017","url":null,"abstract":"Introduction: The aim of this study was to compare the subjective theories of illness in patients with fibroids and patients with endometriosis, and to identify potential factors influencing them. Methodology: Participating patients were recruited via three specialized centers for fibroids and endometriosis. To assess their subjective theories concerning the cause of their illness, we used a questionnaire based on the revised Illness Perceptions Questionnaire (IPQ-R). We also gathered and evaluated data relating to sociodemographic factors and psychological distress or possible anxieties using the Kessler Psychological Distress Scale (K10) and the Generalised Anxiety Disorder Assessment (GAD-7). Results: We were able to analyze data from 201 patients with fibroids and 212 patients with endometriosis. About 94.4% of the patients had one or more subjective theories concerning the cause of their illness. Both groups perceived “stress or worry” to be the most probable cause of their illness. Compared to endometriosis patients, patients with fibroids were more likely to assume “aging” and “heredity” as the cause of their illness. Endometriosis patients, on the other hand, were more likely to choose theories pertaining to the “environmental influences and immune system” category. The patients’ age, formal education, and conspicuous score values in the K10 or GAD-7 questionnaire proved to be important factors influencing their beliefs about the cause of illness. Conclusion: Patients perceive stress and psychological strain as possible causes for their illness. It might be beneficial to take this information into account in conversations between doctors and patients and when drawing up psychosomatic-gynecological treatment plans.","PeriodicalId":15725,"journal":{"name":"Journal of endometriosis and pelvic pain disorders","volume":"14 1","pages":"71 - 79"},"PeriodicalIF":0.5,"publicationDate":"2022-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42728148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Efficacy of excision versus ablation for improving endometriosis related pain: A systematic review and meta-analysis 切除与消融改善子宫内膜异位症相关疼痛的疗效:系统回顾和荟萃分析

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Journal of endometriosis and pelvic pain disorders Pub Date : 2022-02-09 DOI: 10.1177/22840265221074850

C. Ouyang, Amy Fitch, K-S Cho, Jenna Driscoll, Alexander S. Wang, G. Lamvu

{"title":"Efficacy of excision versus ablation for improving endometriosis related pain: A systematic review and meta-analysis","authors":"C. Ouyang, Amy Fitch, K-S Cho, Jenna Driscoll, Alexander S. Wang, G. Lamvu","doi":"10.1177/22840265221074850","DOIUrl":"https://doi.org/10.1177/22840265221074850","url":null,"abstract":"Background: Surgical treatment of superficial peritoneal endometriosis includes excision or ablation. Controversy exists about which method is better for providing pain relief. We performed a meta-analysis of randomized control trials (RCTs) comparing the efficacy of excision versus ablation for improving the most frequently encountered endometriosis pain symptoms: dysmenorrhea, dyspareunia, non-cyclic pelvic pain, and dyschezia. Methods: A search from inception to May 2020 was conducted in PubMed, MEDLINE, Clinicaltrials.gov, Cochrane Central Register of Controlled Trials, and Web of Science. RCTs comparing excision versus ablation for peritoneal endometriosis were included if they assessed dysmenorrhea, dyspareunia, dyschezia, and pelvic pain/non-menstrual pain. Exclusion criteria included extra-peritoneal endometriosis or endometriomas, and non-English publications. Publications were assessed for risk of bias and quality of evidence using Cochrane risk of bias tool (RoB 2) and GradePro. Results: Of the 2025 records identified initially, four met inclusion criteria. The sample sizes of the included studies ranged from 24 to 133 participants. The excision and ablation groups included 204 participants each. There was no difference after excision or ablation for dysmenorrhea when comparing the mean change in pain scores from baseline to 12 months after surgery (−0.31, 95% CI −1.66, 1.04, p = 0.65), dyspareunia (−0.24, 95% CI −1.78, 1.30, p = 0.76), dyschezia (−0.72, 95% CI −1.94, 0.50, p = 0.25), or non-cyclic pain (−0.78, 95% CI −2.47, 0.91, p = 0.37). Conclusions: We found low to moderate quality evidence suggesting that neither excision nor ablation is superior in reduction of endometriosis-related pain up to 12 months after surgery.","PeriodicalId":15725,"journal":{"name":"Journal of endometriosis and pelvic pain disorders","volume":"14 1","pages":"52 - 62"},"PeriodicalIF":0.5,"publicationDate":"2022-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45921442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adverse childhood events and substance use history or recent opioid use among women with chronic pelvic pain 慢性盆腔疼痛妇女的儿童不良事件和药物使用史或近期阿片类药物使用情况

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Journal of endometriosis and pelvic pain disorders Pub Date : 2022-01-27 DOI: 10.1177/22840265211072975

Jamie Griego, T. Petersen, Y. Komesu, N. Andrews, K. Meriwether

{"title":"Adverse childhood events and substance use history or recent opioid use among women with chronic pelvic pain","authors":"Jamie Griego, T. Petersen, Y. Komesu, N. Andrews, K. Meriwether","doi":"10.1177/22840265211072975","DOIUrl":"https://doi.org/10.1177/22840265211072975","url":null,"abstract":"Introduction: We aimed describe the association of adverse childhood events (ACEs) with a history of substance use disorder and recent opioid use among women with chronic pelvic pain (CPP). Methods: This cohort study investigated two data sets of women presenting to subspecialty gynecologic and pelvic floor disorder clinics where questionnaires querying substance use disorder, opioid use in the last 3 months, and ACEs (BRFSS-ACE questionnaire) were obtained. We compared the recent opioid use, morphine milligram equivalents (MMEs) per dose, pills used per month, and minimum MMEs reported per month between women with high (⩾4) or low (<4) reported ACEs. Results: Patients completing the BRFSS-ACE (n = 113) were older, more likely to be Hispanic/Latina, had higher levels of education, a higher prevalence of pain syndromes, and a greater degree of bother from pelvic floor disorders than those not completing the BRFSS-ACE. Women reporting a high number of (⩾4) ACEs (n = 56) were younger, less likely to identify as Hispanic, had higher co-occurrence of fibromyalgia and IBS, and a higher prevalence of a history of substance use disorder (18% vs 2%, p < 0.01) than women with low (<4) ACEs (n = 57). High ACEs were not significantly associated with recent opioid use (43% vs 39%, p = 0.83), opioid pills used per month, MMEs per dose, or the minimum MMEs used per month. Conclusion: Women with CPP reporting higher numbers of ACEs are more likely to report a history of substance use disorder but were not more likely to have used opioids in the last 3 months.","PeriodicalId":15725,"journal":{"name":"Journal of endometriosis and pelvic pain disorders","volume":"14 1","pages":"43 - 51"},"PeriodicalIF":0.5,"publicationDate":"2022-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49634762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Painful catamenial vulvar lesions misleading gynecologist 疼痛的肛管外阴病变误导妇科医生

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Journal of endometriosis and pelvic pain disorders Pub Date : 2022-01-10 DOI: 10.1177/22840265211067126

Ş. Yıldız, Esra Bilir, Bahar Yilmaz Dikmen, P. Bulutay, E. Turkgeldi, B. Ata

引用次数: 0

Prevalence and determinants of ectopic pregnancy in Ethiopia: Systematic review and meta-analysis 埃塞俄比亚异位妊娠的患病率和决定因素：系统综述和荟萃分析

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Journal of endometriosis and pelvic pain disorders Pub Date : 2022-01-03 DOI: 10.1177/22840265211062010

A. Ayenew

{"title":"Prevalence and determinants of ectopic pregnancy in Ethiopia: Systematic review and meta-analysis","authors":"A. Ayenew","doi":"10.1177/22840265211062010","DOIUrl":"https://doi.org/10.1177/22840265211062010","url":null,"abstract":"Background: Ectopic pregnancy is a life-threatening obstetric emergency, and is a major health problem for women of fertile age. Therefore, the aim of this systematic review and meta-analysis was to estimate the prevalence, determinant factors, and outcomes of ectopic pregnancy among fertile age women in Ethiopia. Method: International databases (MEDLINE/Pub Med, Hinari, Scopus, Google scholar, African journals, and literatures were searched and nine eligible cross sectional and two case control studies were included in this systematic review and meta-analysis. Eggers test and funnel plot were computed to check publication bias across the studies. Publication bias was computed using a funnel plot and eggers test. Heterogeneity of the studies was checked using Cochrane Q-test and I2 statistic. Results: The pooled prevalence of ectopic pregnancy in Ethiopia was 3.61% (95%CI: 2.24–4.98, I2 = 89.2.0%, p < 0.001). Having cesarean section scar (AOR = 7.44, 95%CI: 5.48–10.09), single marital status (AOR = 5.71, 95%CI: 4.76–6.85), history of sexually transmitted infection (AOR = 4.68, 95%CI: 3.04–7.19), history of abortion (AOR = 3.89, 95%CI: 3.35–4.52), history of ectopic pregnancy (AOR = 5.74, 95%CI: 3.81–8.65), and emergency contraceptive use (AOR = 8.72, 95%CI: 2.90–26.20) were the determinant factors for the occurrence of ectopic pregnancy. Conclusion: This systematic review and meta-analysis showed that the prevalence of ectopic pregnancy was high in Ethiopia. Thus, educating women to limit the number of sexual partners, smoking cessation, using a condom during sex helps prevent sexually transmitted infections and the risk of pelvic inflammatory disease is crucial.","PeriodicalId":15725,"journal":{"name":"Journal of endometriosis and pelvic pain disorders","volume":"14 1","pages":"25 - 42"},"PeriodicalIF":0.5,"publicationDate":"2022-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49371865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retinoic acid action is altered within endometrium of baboons affected with endometriosis 患有子宫内膜异位症的狒狒子宫内膜内的维甲酸作用发生改变

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Journal of endometriosis and pelvic pain disorders Pub Date : 2022-01-03 DOI: 10.1177/22840265211062008

M. Pavone, Allison R. Grover, R. Confino, E. Pearson, Saurabh S. Malpani, Youhong Cheng, A. Fazleabas, S. Bulun

{"title":"Retinoic acid action is altered within endometrium of baboons affected with endometriosis","authors":"M. Pavone, Allison R. Grover, R. Confino, E. Pearson, Saurabh S. Malpani, Youhong Cheng, A. Fazleabas, S. Bulun","doi":"10.1177/22840265211062008","DOIUrl":"https://doi.org/10.1177/22840265211062008","url":null,"abstract":"Objective: Using a baboon model, we determined the changing expression of Retinoic Acid (RA) target genes during the menstrual cycle and during disease progression. This change could explain the cellular response and changes characteristic of endometriosis. In previous studies, we established that endometriosis affects the CRABP2:FABP5 ratio in an in vitro environment, shifting toward apoptosis and differentiation with higher CRABP2, and anti-apoptosis with higher levels of FABP5. Intervention(s): Endometriosis was induced in female baboons with intraperitoneal inoculation of menstrual endometrium (n = 2–4). Tissue was harvested via endometrectomy during different stages of the menstrual cycle as well at 3, 6, and 12 month timepoints after inoculation with endometriosis. Main outcome measure(s): Real time PCR was used to quantify STRA6 (a gene responsible for retinol uptake), CRABP2 (a gene necessary for apoptotic and anti-apoptotic estrogenic RA effects), and FABP5 (a gene that mediates the anti-apoptotic actions of RA). Results: STRA6 and CRABP2 expression were highest in the proliferative phase and lowest in the late secretory phase. FABP5 expression remained stable throughout the 12 months following the induction of the disease, whereas STRA6 and CRABP2 continued to decrease during the same period. Conclusions: Our study confirms that a shift in the CRABP2:FABP5 ratio has similar in vivo effects as it does in vitro: changing RA expression with disease induction and progression. As CRABP2 may be important in determining cell fate in the endometrium, gene expression changes could contribute to the anti-apoptotic behavior of affected cells. As expression changes more during progression, earlier rather than later treatment becomes more critical in reducing the rate of disease progression.","PeriodicalId":15725,"journal":{"name":"Journal of endometriosis and pelvic pain disorders","volume":"14 1","pages":"19 - 24"},"PeriodicalIF":0.5,"publicationDate":"2022-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48617664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Body mass index and vitamin D as risk factors for the development of uterine leiomyomas in Mexican women 体重指数和维生素D是墨西哥妇女子宫平滑肌瘤发生的危险因素

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Journal of endometriosis and pelvic pain disorders Pub Date : 2021-12-20 DOI: 10.1177/22840265211065226

Luz A Huseman-Plascencia, Francisco Villa-Villagrana, Alberto Ballesteros-Manzo, Raúl C Baptista Rosas, A. Mercado-Sesma, Mar I Arámbula-Chavolla

{"title":"Body mass index and vitamin D as risk factors for the development of uterine leiomyomas in Mexican women","authors":"Luz A Huseman-Plascencia, Francisco Villa-Villagrana, Alberto Ballesteros-Manzo, Raúl C Baptista Rosas, A. Mercado-Sesma, Mar I Arámbula-Chavolla","doi":"10.1177/22840265211065226","DOIUrl":"https://doi.org/10.1177/22840265211065226","url":null,"abstract":"Objective: The objective of the present study was to determine if body mass index and vitamin D levels are risk factors for the development of uterine leiomyomas in Mexican women. Methods: A cross-sectional study was designed. Inclusion criteria were women between 20 and 55 years with a suspect of uterine leiomyomas. Transvaginal ultrasonography was made to confirm the diagnosis and clinical variables were collected. Vitamin D levels were measured in serum by chemiluminescence immunoassay. Binary linear regression analysis was conducted to assess the predictors of uterine leiomyomas. Results: A total of 106 patients were evaluated, the mean age was 41.4 ± 8.0 years. The serum levels of vitamin D were insufficient in 94 (88.7%) and 82 (77.3%) has overweight or obesity. However, only 50 (47.2%) of participants have a diagnostic of uterine leiomyomas. BMI not increased the probability of having insufficient levels of vitamin D or uterine leiomyomas. Only, age (> 45 years) and levels of vitamin D (<30 ng/mL) were predictors of uterine leiomyomas (OR 10.345, 95% CI 2.737–39.095; p = 0.001; and OR 2.26, 95% CI 1.011–5.073; p = 0.014), respectively. Conclusions: Insufficient levels of vitamin D are common in Mexican women. Age and hypovitaminosis D are possible risk factors in the development of uterine leiomyomas in Mexican women.","PeriodicalId":15725,"journal":{"name":"Journal of endometriosis and pelvic pain disorders","volume":"14 1","pages":"14 - 18"},"PeriodicalIF":0.5,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42279274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2