Warren Stern, Alaei Parham, Ross Berbeco, Larry A. DeWerd, Jacob Kamen, Carolyn MacKenzie, Eduardo G. Moros, Yannick Poirier, Charles A. Potter, Dörthe Schaue, Ileana Silvestre Patallo, Michael Abend, Steven Swarts, François Trompier
{"title":"Recommendations for harmonized reporting of radiation Dosimetry by adoption of Compatibility in Irradiation Research Protocols Expert Roundtable (CIRPER)","authors":"Warren Stern, Alaei Parham, Ross Berbeco, Larry A. DeWerd, Jacob Kamen, Carolyn MacKenzie, Eduardo G. Moros, Yannick Poirier, Charles A. Potter, Dörthe Schaue, Ileana Silvestre Patallo, Michael Abend, Steven Swarts, François Trompier","doi":"10.1080/09553002.2024.2331130","DOIUrl":"https://doi.org/10.1080/09553002.2024.2331130","url":null,"abstract":"Published in International Journal of Radiation Biology (Ahead of Print, 2024)","PeriodicalId":14261,"journal":{"name":"International Journal of Radiation Biology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140596280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dietary agents in the prevention of radiation-induced nausea and vomiting (RINV): review addressing the scientific observations, benefits, lacunae and future direction","authors":"Princy Louis Palatty, Dhanya Sacheendran, Shamprasad Varija Raghu, Rajesh Arora, Suresh Rao, Manjeshwar Shrinath Baliga","doi":"10.1080/09553002.2024.2309899","DOIUrl":"https://doi.org/10.1080/09553002.2024.2309899","url":null,"abstract":"Radiation-induced Nausea and Vomiting (RINV) is an important side effect and conservative estimates are that 50–80% of the patients undergoing curative radiotherapy (RT) will experience some sought...","PeriodicalId":14261,"journal":{"name":"International Journal of Radiation Biology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140168385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ali Vegari, Akbar Abdisaray, Kamal Mostafanejad, Nasrollah Jabbari
{"title":"High-density polyethylene (HDPE)-incorporated boron carbide and boric acid nanoparticles as a nanoshield of photoneutrons from medical linear accelerators","authors":"Ali Vegari, Akbar Abdisaray, Kamal Mostafanejad, Nasrollah Jabbari","doi":"10.1080/09553002.2023.2295964","DOIUrl":"https://doi.org/10.1080/09553002.2023.2295964","url":null,"abstract":"The current study aimed to investigate boron carbide and boric acid nanoparticles (NPs) as absorbents for thermal neutrons and high-density polyethylene (HDPE) as a substrate and neutron moderator ...","PeriodicalId":14261,"journal":{"name":"International Journal of Radiation Biology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139397382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Amrenova, E. Ainsbury, C. Baudin, A. Giussani, J. Lochard, W. Rühm, P. Scholz-Kreisel, K. Trott, L. Vaillant, R. Wakeford, F. Zölzer, D. Laurier
{"title":"Consideration of hereditary effects in the radiological protection system: evolution and current status","authors":"A. Amrenova, E. Ainsbury, C. Baudin, A. Giussani, J. Lochard, W. Rühm, P. Scholz-Kreisel, K. Trott, L. Vaillant, R. Wakeford, F. Zölzer, D. Laurier","doi":"10.1080/09553002.2023.2295289","DOIUrl":"https://doi.org/10.1080/09553002.2023.2295289","url":null,"abstract":"The purpose of this paper is to provide an overview of the methodology used to estimate radiation genetic risks and quantify the risk of hereditary effects as outlined in the ICRP Publication 103. ...","PeriodicalId":14261,"journal":{"name":"International Journal of Radiation Biology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139397442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Olivia Molinar-Inglis, Andrea L. DiCarlo, Paula J. Lapinskas, Carmen I. Rios, Merriline M. Satyamitra, Toby A. Silverman, Thomas A. Winters, David R. Cassatt
{"title":"Radiation-induced multi-organ injury","authors":"Olivia Molinar-Inglis, Andrea L. DiCarlo, Paula J. Lapinskas, Carmen I. Rios, Merriline M. Satyamitra, Toby A. Silverman, Thomas A. Winters, David R. Cassatt","doi":"10.1080/09553002.2023.2295298","DOIUrl":"https://doi.org/10.1080/09553002.2023.2295298","url":null,"abstract":"Natural history studies have been informative in dissecting radiation injury, isolating its effects, and compartmentalizing injury based on the extent of exposure and the elapsed time post-irradiat...","PeriodicalId":14261,"journal":{"name":"International Journal of Radiation Biology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139077949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Characterization of sugarcane mutants developed through gamma irradiations for their lignin content and caffeic acid-O-methyl transferase (COMT) gene mutations","authors":"Shaweta Sharma, Pawan Kumar Malhotra, Meenakshi Goyal, Vishal Sharma, Amandeep Mittal, Inderjit Singh Yadav, Gulzar Singh Sanghera, Parveen Chhuneja","doi":"10.1080/09553002.2023.2295962","DOIUrl":"https://doi.org/10.1080/09553002.2023.2295962","url":null,"abstract":"Bagasse, the residue left after extracting juice from sugarcane stalks, is rich in lignocellulosic biomass. The lignin present in this plant biomass is the key factor that hinders the efficient ext...","PeriodicalId":14261,"journal":{"name":"International Journal of Radiation Biology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139077956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Computational model of radiation oxygen effect with Monte Carlo simulation: effects of antioxidants and peroxyl radicals","authors":"Ankang Hu, Wanyi Zhou, Rui Qiu, Shuoyang Wei, Zhen Wu, Hui Zhang, Junli Li","doi":"10.1080/09553002.2023.2295292","DOIUrl":"https://doi.org/10.1080/09553002.2023.2295292","url":null,"abstract":"Oxygen plays a crucial role in radiation biology. Antioxidants and peroxyl radicals affect the oxygen effect greatly. This study aims to establish a computational model of the oxygen effect and exp...","PeriodicalId":14261,"journal":{"name":"International Journal of Radiation Biology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139077997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Miriam Conte, Maria Silvia De Feo, Viviana Frantellizzi, Francesco Marampon, Luca Filippi, Orazio Schillaci, Giuseppe De Vincentis
{"title":"Extraosseous distribution of <sup>99m</sup>Tc-diphosphonates during bone scintigraphy: review of the literature with case series presentation.","authors":"Miriam Conte, Maria Silvia De Feo, Viviana Frantellizzi, Francesco Marampon, Luca Filippi, Orazio Schillaci, Giuseppe De Vincentis","doi":"10.1080/09553002.2023.2242935","DOIUrl":"10.1080/09553002.2023.2242935","url":null,"abstract":"<p><strong>Purpose: </strong>Technetium-99m (<b><sup>99m</sup></b>Tc)-diphosphonates represent the most common radiopharmaceutical used for bone scintigraphy. Even if the uptake in bone tissue has been widely explored, atypical uptake could be seen in soft tissue malignancies during bone scintigraphy. Increased vascularization and endothelium permeability represent front-row players in the biodistribution of the tracer, albeit other causes have been identified such as trauma, necrosis, the presence of calcification in metastasis, the pH of the tissue and consequently the type of ion concentration.</p><p><strong>Conclusion: </strong>The aim of this paper is to summarize the state of art of atypical soft tissue uptake seen in cancer tissues. The research was conducted on PubMed. The analysis of the literature suggests that calcium metabolism and ionic saturation have a pivotal role in the biodistribution of bone tracers. This phenomenon ranks in a complex scenario that includes carcinogenesis and cancer environment aspects. We also report two cases in our Institution in which atypical uptake in cancer tissues was observed.</p>","PeriodicalId":14261,"journal":{"name":"International Journal of Radiation Biology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9964761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Simone Schüle, Patrick Ostheim, Razan Muhtadi, Samantha Stewart, Gwendolyn Kaletka, Cornelius Hermann, Matthias Port, Michael Abend
{"title":"Evaluating transport conditions of conventional, widely used EDTA blood tubes for gene expression analysis in comparison to expensive, specialized PAXgene tubes in preparedness for radiological and nuclear events.","authors":"Simone Schüle, Patrick Ostheim, Razan Muhtadi, Samantha Stewart, Gwendolyn Kaletka, Cornelius Hermann, Matthias Port, Michael Abend","doi":"10.1080/09553002.2023.2250871","DOIUrl":"10.1080/09553002.2023.2250871","url":null,"abstract":"<p><strong>Purpose: </strong>Gene expression (GE) analysis of a radio-sensitive gene set (<i>FDXR, DDB2, WNT3, POU2AF1</i>) has been introduced in the last decade as an early and high-throughput prediction tool of later developing acute hematologic radiation syndrome (H-ARS) severity. The use of special tubes for RNA extraction from peripheral whole blood (PAXgene) represent an established standard in GE studies, although uncommonly used in clinics and not immediately available in the quantities needed in radiological/nuclear (R/N) incidents. On the other hand, EDTA blood tubes are widely utilized in clinical practice.</p><p><strong>Material and methods: </strong>Using blood samples from eleven healthy donors, we investigated GE changes associated with delayed processing of EDTA tubes up to 4 h at room temperature (RT) after venipuncture (simulating delays caused by daily clinical routine), followed by a subsequent transport time of 24 h at RT, 4 °C, and -20 °C. Differential gene expression (DGE) of the target genes was further examined after X-irradiation with 0 Gy and 4 Gy under optimal transport conditions.</p><p><strong>Results: </strong>No significant changes in DGE were observed when storing EDTA whole blood samples up to 4 h at RT and subsequently kept at 4 °C for 24 h which is in line with expected DGE. However, other storage conditions, such as -20 °C or RT, decreased RNA quality and/or (significantly) caused changes in DGE exceeding the known methodological variance of the qRT-PCR.</p><p><strong>Conclusion: </strong>Our data indicate that the use of EDTA whole blood tubes for GE-based H-ARS severity prediction is comparable to the quality of PAXgene tubes, when processed ≤ 4 h after venipuncture and the sample is transported within 24 hours at 4 °C.</p>","PeriodicalId":14261,"journal":{"name":"International Journal of Radiation Biology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10170442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rupinder Kaur, Sat Pal Sharma, Anu Kalia, Navraj Kaur, Pooja Manchanda
{"title":"<i>In vitro</i> induction and selection of mutants obtained through gamma irradiation with improved processing traits in potato (<i>Solanum tuberosum</i> L.).","authors":"Rupinder Kaur, Sat Pal Sharma, Anu Kalia, Navraj Kaur, Pooja Manchanda","doi":"10.1080/09553002.2023.2245472","DOIUrl":"10.1080/09553002.2023.2245472","url":null,"abstract":"<p><strong>Purpose: </strong>This manuscript aimed for the generation of γ-irradiation derived mutants of potato genotype PAU/RR-1501 possessing desirable processing traits.</p><p><strong>Materials and methods: </strong>Nodal cuttings from virus-free explants were established on basal MS medium and irradiated with different doses (0, 5, 10 and 20 Gy) of γ-irradiation. The 5 and 10 Gy treated plantlets were multiplied and used for micro-tuber induction. Harvested micro-tubers were planted in pots for the selection and evaluation of mutants in M1V2 generation.</p><p><strong>Results: </strong>Four weeks post-treatment, plantlets (5 Gy) showed enhanced growth as compared to the control while 20 Gy treatment exhibited completely ceased shoot growth. The highest number and weight of mini-tubers per plant was recorded for 10 Gy followed by 5 Gy treatment as compared to control. The γ-irradiation treatments caused changes in the skin color and shape of M1V2 tubers.</p><p><strong>Conclusion: </strong>Under the 5 Gy treatment 49.9% of clones produced exhibited cream and 8.53% brown skin color. Nine putative mutants were identified in genotype PAU/RR-1501 exhibiting promising processing traits.</p>","PeriodicalId":14261,"journal":{"name":"International Journal of Radiation Biology","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10050650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}