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The mechanism and research progress of circRNA-microRNA in regulating osteogenesis circRNA-microRNA调控成骨的机制及研究进展
Frontiers in Medical Science Research Pub Date : 2021-06-30 DOI: 10.25236/FMSR.2021.030309
Yizhi Dong, Shuai Shan, Xiangzhen Han, Y. Pu, Weizhe Yang, Hui-hua He
{"title":"The mechanism and research progress of circRNA-microRNA in regulating osteogenesis","authors":"Yizhi Dong, Shuai Shan, Xiangzhen Han, Y. Pu, Weizhe Yang, Hui-hua He","doi":"10.25236/FMSR.2021.030309","DOIUrl":"https://doi.org/10.25236/FMSR.2021.030309","url":null,"abstract":"Jaw defect and alveolar bone absorption are the main oral problems in today’s society. In recent years, studies have found that changes in the expression of different miRNAs can affect the osteogenic effects of stem cells. With the in-depth study of its upstream circRNA, it has been found that circRNA can pass it acts as a molecular sponge of microRNA to indirectly regulate osteogenesis, so how to select a suitable and stable circRNA has become the focus of attention. In this review, we have collected and sorted out circRNA and its functions, the application and process of mirRNA to regulate osteogenic differentiation, and a list of several miRNAs closely related to osteogenesis and relatively mature researches, aiming to find suitable circRNA upstream Therefore, it is expected to be used in the clinical repair of oral bone defects.","PeriodicalId":129141,"journal":{"name":"Frontiers in Medical Science Research","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132519513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Design and application of medical image remote transmission system 医学图像远程传输系统的设计与应用
Frontiers in Medical Science Research Pub Date : 2021-06-25 DOI: 10.25236/FMSR.2021.030308
Xiaolei Han, Wenming Xu
{"title":"Design and application of medical image remote transmission system","authors":"Xiaolei Han, Wenming Xu","doi":"10.25236/FMSR.2021.030308","DOIUrl":"https://doi.org/10.25236/FMSR.2021.030308","url":null,"abstract":"In order to solve the problem of long transmission time in the practical application of hospital image transmission system, which leads to low transmission efficiency and unable to realize the efficient use of limited resources, the design and Application Research of medical image remote transmission system is carried out. Through the hardware design of host computer display screen selection and web server selection, and the software design of medical image remote transmission protocol selection and analysis of medical image remote transmission content, A new transmission system is proposed. Experiments show that under the same number of images, the new system has shorter transmission time and higher transmission efficiency.","PeriodicalId":129141,"journal":{"name":"Frontiers in Medical Science Research","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125822132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk factors and preventive measures related to osteoporosis inthe elderly 老年人骨质疏松的危险因素及预防措施
Frontiers in Medical Science Research Pub Date : 2021-06-20 DOI: 10.25236/FMSR.2021.030307
Tian Jiaying, Tan Longwang
{"title":"Risk factors and preventive measures related to osteoporosis inthe elderly","authors":"Tian Jiaying, Tan Longwang","doi":"10.25236/FMSR.2021.030307","DOIUrl":"https://doi.org/10.25236/FMSR.2021.030307","url":null,"abstract":"The aging situation in China is becoming more and more serious, which has become a major social problem. The prevalence of osteoporosis and other common diseases of the elderly is increasing year by year. It is predicted that by 2050, the number of osteoporosis fractures in China will reach 5.99 million, and the corresponding medical expenditure will reach 174.5 billion yuan [1]. It is of great social significance to study the risk factors and preventive measures of osteoporosis, which can better allocate social resources and play a guiding role in decision-making in the field of public health. This study not only brings good news to patients with osteoporosis, relieving their pain, but also promotes the supplement of relevant medical literature and the progress of medical technology, and provides a guarantee for the elderly at the clinical stage.","PeriodicalId":129141,"journal":{"name":"Frontiers in Medical Science Research","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132897852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of community management on diabetes prevention and treatment 社区管理对糖尿病防治的影响
Frontiers in Medical Science Research Pub Date : 2021-06-11 DOI: 10.25236/FMSR.2021.030304
Bao-xin Li
{"title":"Effect of community management on diabetes prevention and treatment","authors":"Bao-xin Li","doi":"10.25236/FMSR.2021.030304","DOIUrl":"https://doi.org/10.25236/FMSR.2021.030304","url":null,"abstract":"Objective: To explore the effect of community management on diabetes prevention and treatment. Methods: The clinical data of 86 diabetic patients were analyzed retrospectively. Patients were randomly divided into control group and intervention group according to random number table method, with 43 cases in each group. They were given comprehensive treatment such as diabetes education, diet control, exercise therapy, drug therapy and blood glucose monitoring. At the same time, the general situation and SF-36 scale were investigated to analyze the influencing factors. Results: The patients' quality of life improved significantly before and after the intervention, and the scores of general health, physiological function, mental health and vitality were significantly different before and after the intervention. Before and after the intervention, the compliance rate of blood glucose control in the intervention group changed obviously. After 1.5 years of follow-up management and comprehensive intervention, the blood glucose control rate in the intervention group was improved obviously. Conclusion: Extensive use of community management and community therapy can stabilize patients' condition, promote patients' rehabilitation, and make patients more cooperative with treatment.","PeriodicalId":129141,"journal":{"name":"Frontiers in Medical Science Research","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134320814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Discussion on the treatment of children's mental retardation from heart and spleen based on brain gut axis theory 基于脑肠轴理论的心脾治疗儿童智力低下的探讨
Frontiers in Medical Science Research Pub Date : 2021-06-11 DOI: 10.25236/FMSR.2021.030305
Yu Lv, Yu-Ting Liu
{"title":"Discussion on the treatment of children's mental retardation from heart and spleen based on brain gut axis theory","authors":"Yu Lv, Yu-Ting Liu","doi":"10.25236/FMSR.2021.030305","DOIUrl":"https://doi.org/10.25236/FMSR.2021.030305","url":null,"abstract":"The theory of brain gut axis provides a new idea for the clinical treatment of brain gut related diseases. The incidence rate of children with mental retardation has been increasing year by year, and it has become a key problem that affects children's growth and development urgently. As a new research target, brain gut axis theory has an inseparable connection with this disease. Therefore, this paper aims to explore the relationship between the theory of brain gut axis and the treatment of children's mental retardation from the heart and spleen in traditional Chinese medicine, it also explores the scientific connotation of traditional medicine and modern medicine, in order to provide a new perspective for the clinical treatment of children with mental retardation.","PeriodicalId":129141,"journal":{"name":"Frontiers in Medical Science Research","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114393530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of cervical spondylotic radiculopathy by posterior foraminal resection of nucleus pulposus 椎间孔后髓核切除术治疗神经根型颈椎病
Frontiers in Medical Science Research Pub Date : 2021-06-11 DOI: 10.25236/FMSR.2021.030303
Z. Cao, P. Sup
{"title":"Treatment of cervical spondylotic radiculopathy by posterior foraminal resection of nucleus pulposus","authors":"Z. Cao, P. Sup","doi":"10.25236/FMSR.2021.030303","DOIUrl":"https://doi.org/10.25236/FMSR.2021.030303","url":null,"abstract":"To introduce the surgical technique of percutaneous posterior foraminal resection of cervical disc herniation in our hospital and the clinical results of 1 case.[Methods] Imaging diagnosis was C6-7 disc herniation and compression of left nerve root and dural sac. After adequate preoperative preparation, posterior foraminal resection of cervical disc herniation was performed.[Results] The prolapsed nucleus pulposus tissue was removed successfully, and the pain and numbness symptoms of the patient's neck and shoulder were improved on the first day after surgery, and the surgical incision healed well. One week later, the range of motion of the cervical spine and the function of the vertebral body were restored, and the pain and numbness symptoms completely disappeared.[Conclusion] Nucleus pulposus excision by posterior percutaneous foraminal approach in the treatment of cervical disc herniation has good clinical effect and prognosis.","PeriodicalId":129141,"journal":{"name":"Frontiers in Medical Science Research","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126451382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of lycopene on hepatotoxicity induced by perfluorooctane sulfonic acid in rats 番茄红素对全氟辛烷磺酸致大鼠肝毒性的影响
Frontiers in Medical Science Research Pub Date : 2021-06-11 DOI: 10.25236/FMSR.2021.030306
Yinni He, Juan Tang, Qingguo Liu
{"title":"Effect of lycopene on hepatotoxicity induced by perfluorooctane sulfonic acid in rats","authors":"Yinni He, Juan Tang, Qingguo Liu","doi":"10.25236/FMSR.2021.030306","DOIUrl":"https://doi.org/10.25236/FMSR.2021.030306","url":null,"abstract":"Objective: Intend to observe the liver injury induced by perfluorooctane sulfonic acid (PFOS) in SD rats and the protective effect of lycopene (LP) and its possible mechanism. Methods: 48 SD rats were randomly divided into 8 groups. The solvent control group of LP protection group and LP protection low, middle and high dose PFOS exposure groups were given LP suspension once a day according to their designed dose. The contents of ALT, ASP and AST in serum, the content of MDA in liver tissue and the activity of SOD and GSH-Px in liver tissue were measured after 2 months. Results: The levels of serum ALT, AST and serum ASP enzyme activity in middle and high dose PFOS groups and high dose PFOS groups were significantly higher than those in solvent control group (P","PeriodicalId":129141,"journal":{"name":"Frontiers in Medical Science Research","volume":"80 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116522449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of acarbose on the gut microbiota: an evidence-based review 阿卡波糖对肠道微生物群的影响:一项基于证据的综述
Frontiers in Medical Science Research Pub Date : 2021-06-05 DOI: 10.25236/FMSR.2021.030302
Xianhe Zheng, Zhong-rong Zhang, Jiangchuan Xie
{"title":"The effect of acarbose on the gut microbiota: an evidence-based review","authors":"Xianhe Zheng, Zhong-rong Zhang, Jiangchuan Xie","doi":"10.25236/FMSR.2021.030302","DOIUrl":"https://doi.org/10.25236/FMSR.2021.030302","url":null,"abstract":"Acabose is wildly used in various disease treatments and could interact with the gut flora, while the gut flora plays a significant role in human body. This means that acarbose is able to be utilized to improve the efficacy and patient experience by measuring and regulating intestinal flora to achieve precise medicine intake. Moreover, it is also capable to be employed for treating and preventing more other diseases by targeting the gut flora to open up new uses. Based on this hypothesis, we summarized the reasons, methods and results of the interactions between acarbose and intestinal flora, as well as ways for health promotion according to existing experimental results and literature reviews.","PeriodicalId":129141,"journal":{"name":"Frontiers in Medical Science Research","volume":"112 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117202487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Study of the Ecological Community Model of Independent Innovation of Biomedical Industry in China 中国生物医药产业自主创新生态群落模式研究
Frontiers in Medical Science Research Pub Date : 2021-06-05 DOI: 10.25236/FMSR.2021.030301
Xia Yu
{"title":"A Study of the Ecological Community Model of Independent Innovation of Biomedical Industry in China","authors":"Xia Yu","doi":"10.25236/FMSR.2021.030301","DOIUrl":"https://doi.org/10.25236/FMSR.2021.030301","url":null,"abstract":"This paper first analyzes the status quo of and problems with independent innovation of biomedical industry in China and uses ecological theory to analyze the ecological community characteristics and models of the independent innovation system of biomedical industry, holding that balanced ecological community model can promote the development of biomedical industry.","PeriodicalId":129141,"journal":{"name":"Frontiers in Medical Science Research","volume":"241 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132902756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of the Value of X-ray and CT in the Health Examination of Children with Sinusitis x线与CT在儿童鼻窦炎健康检查中的价值分析
Frontiers in Medical Science Research Pub Date : 2021-05-13 DOI: 10.25236/FMSR.2021.030211
Qingru Hu, Bin-Han Huang, Hong-liang Qi
{"title":"Analysis of the Value of X-ray and CT in the Health Examination of Children with Sinusitis","authors":"Qingru Hu, Bin-Han Huang, Hong-liang Qi","doi":"10.25236/FMSR.2021.030211","DOIUrl":"https://doi.org/10.25236/FMSR.2021.030211","url":null,"abstract":"Objective: this research explores the value analysis of X-ray examination and CT examination in the health examination of children with sinusitis. Methods: this research selected 124 cases of paranasal sinusitis diagnosed and treated in our hospital from March 2017 to July 2019 to undergo X-ray examination and CT coronal scan, and compare the conditions of the patients after the two examination methods. Analysis. In this research, the children who participated in the study were divided into two groups according to the random allocation method. The CT group of pediatric sinusitis patients underwent CT examination, and the X-ray group pediatric sinusitis patients underwent X-ray examination. The CT examination group and X-ray examination were compared and analyzed. The clinical examination effect of the group, so as to compare and analyze the application value of the two examination methods. Results: The positive detection rate of CT group was much higher than that of X-ray examination group. Spiral CT can reconstruct images from different angles at the maximum density, and can be as clear as possible of the lesion location and signs, so as to prepare for the next surgical treatment. X-ray examination cannot clearly and accurately show the degree of mucosal thickening, nor can it diagnose ethmoid sinus and other diseases. The differences in the data inspection results between the two groups were statistically significant (P","PeriodicalId":129141,"journal":{"name":"Frontiers in Medical Science Research","volume":"126 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127397614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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