Turkish Journal of Clinics and Laboratory最新文献_第9页

The Effect of Surgical Treatment Option on Inflammatory Response in Breast Cancers 手术治疗方案对乳腺癌炎症反应的影响

Turkish Journal of Clinics and Laboratory Pub Date : 2023-06-30 DOI: 10.18663/tjcl.1310277

V. Kinaş, Özgür Albuz, Husnu Mersin

引用次数: 0

KLİNİKOPATOLOJİK OLARAK TANI KONAN PULMONER ODAĞI OLMAYAN HEPATOBİLİYER TÜBERKÜLOZ OLGUSU

Turkish Journal of Clinics and Laboratory Pub Date : 2023-05-29 DOI: 10.18663/tjcl.1280090

E. Güven

引用次数: 0

FACTORS AFFECTING ADEQUATE MYOCARDIAL PERFUSION IN PATIENTS WITH ACUTE ST-ELEVATION MYOCARDIAL INFARCTION WITH SUCCESSFUL EPICARDIAL FLOW 影响心外膜血流成功的急性st段抬高型心肌梗死患者充足心肌灌注的因素

Turkish Journal of Clinics and Laboratory Pub Date : 2023-05-15 DOI: 10.18663/tjcl.1205470

F. Aydınyılmaz, N. B. Özbeyaz, Engin Algul, I. Guliyev, H. F. Şahan, Ayşe Nur Özkaya İbiş, K. Kalkan, H. Sunman

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ACİL SERVİSTE İDRAR YOLU ENFEKSİYONU İÇİN BAŞLANAN AMPİRİK ANTİBİYOTİK İLE KÜLTÜR ANTİBİYOGRAM DUYARLILIĞININ KARŞILAŞTIRILMASI

Turkish Journal of Clinics and Laboratory Pub Date : 2023-05-04 DOI: 10.18663/tjcl.1253222

Adem Çakir, H. Acar

引用次数: 0

REAL-LIFE DATA OF PAZOPANIB USAGE IN SOFT TISSUE SARCOMA 帕唑帕尼在软组织肉瘤中的实际应用数据

Turkish Journal of Clinics and Laboratory Pub Date : 2023-05-03 DOI: 10.18663/tjcl.1236710

Oğur Karhan, S. Ileri, Halis Yerlikaya, Muslih Ürün, Y. Sezgin

{"title":"REAL-LIFE DATA OF PAZOPANIB USAGE IN SOFT TISSUE SARCOMA","authors":"Oğur Karhan, S. Ileri, Halis Yerlikaya, Muslih Ürün, Y. Sezgin","doi":"10.18663/tjcl.1236710","DOIUrl":"https://doi.org/10.18663/tjcl.1236710","url":null,"abstract":"Abstract: \u0000Objective: Soft tissue sarcomas are heterogeneous group of malignancies consisting of more than 50 subtypes. Although it is rare, it is usually resistant to chemotherapy and has a poor prognosis. In this study, we planned to investigate the efficacy, tolerability and side-effect profile of pazopanib in metastatic soft tissue sarcomas. \u0000Method-Material: Our study was a single-center retrospective study and included metastatic patients over the age of 18 who were treated with pazopanib. Data of 37 patients were obtained in retrospective medical records. In patients using pazopanib; Tumor location, histological subtype, tumor grade, disease stage, the line at which pazopanib was used, efficacy, tolerability, and side-effect profile of pazopanib were examined. \u0000Findings: The mean age of the patients at diagnosis was 49. Pleomorphic sarcoma was the most common subtype. The progression-free survival (PFS) of patients after first-line therapy was 18 weeks. The median overall survival (OS) of the patients was 20 months. The median PFS with pazopanip was 18 weeks. \u0000Conclusion: In the study we conducted research in terms of effectiveness and side effects; the use of pazopanib in soft tissue sarcoma was found to be effective in terms of both PFS and OS. Side effects were tolerable and treatable. In our study, a PFS of 32 weeks was obtained in patients with hypothyroidism and at 16 weeks in patients who did not. In this respect, development of hypothyroidism may be a predictive parameter for response.","PeriodicalId":120468,"journal":{"name":"Turkish Journal of Clinics and Laboratory","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123776034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

AKUT VE KRONİK KEMİK ÇEKİÇ PARMAK HASTALARININ CERRAHİ TEDAVİ SONUÇLARI

Turkish Journal of Clinics and Laboratory Pub Date : 2023-04-25 DOI: 10.18663/tjcl.1207533

M. N. Selimoğlu, Egemen Altan, Celaleddin Bi̇ldi̇k

引用次数: 0

Evaluation of Mucociliary Clearance in COVID-19 Patients Presenting to the Emergency Department 急诊COVID-19患者纤毛粘膜清除率的评价

Turkish Journal of Clinics and Laboratory Pub Date : 2023-04-17 DOI: 10.18663/tjcl.1246540

S. C. Uzunget, Z. K. Ertürk, Sevinç Bayrak, Hidayet Can Ünal, M. Türkkanı

{"title":"Evaluation of Mucociliary Clearance in COVID-19 Patients Presenting to the Emergency Department","authors":"S. C. Uzunget, Z. K. Ertürk, Sevinç Bayrak, Hidayet Can Ünal, M. Türkkanı","doi":"10.18663/tjcl.1246540","DOIUrl":"https://doi.org/10.18663/tjcl.1246540","url":null,"abstract":"Öz \u0000 Solunum yolu epitelinde yer alan mukosiliyer tabaka, solunum yollarındaki ilk koruma mekanizması olarak görev yapmaktadır. Şiddetli akut solunum sendromu koronavirus-2 de (SARS-Cov-2), diğer bazı solunum yolu virüsleri gibi siliyer hücrelere yapışmakta ve mukosilier aktiviteyi etkilemektedir. Sakkarin testi ile mukosilier klirensin ölçülmesi mümkündür. Çalışmamızda acil servise başvuran hastalarda SARS-CoV 2 ye bağlı olarak gelişen Korona virus hastalığı-2019 (COVİD-19) enfeksiyonunda erken dönemde mukosiliyer klirensin etkisini değerlendirmeyi amaçladık \u0000Gereç ve Yöntem: \u0000Acil servise başvuran ve son 48 saat içerisinde COVID-19 düşündüren yakınmaları olan ve Polimeraz zincir reaksiyonu (PCR) testi çalışılan 84 kişilik hasta grubunda mukosilier klirens zamanı (MCT), sakkarin testi ile ölçülerek sağlıklı gönüllülerde yapılan ölçüm ile karşılaştırılmıştır. \u0000Sonuçlar \u0000PCR pozitif olarak tespit edilen katılmcılarda ortalama MCT 14.58 dakika olarak, sağlıklı gönüllülerde ise ortalama MCT 13.72 dakika olarak ölçüldü. İki grup arasında istatistiksel açıdan fark saptanmadı (p=0,657). \u0000Tartışma \u0000COVID-19 etkeni olan SARS-CoV-2’nin solunum yolu epiteli hasarı yaptığı ve solunum yollarında hastalık oluşturduğu bilinmektedir. Erken dönemde yapılan PCR testlerinde üst solunum yolu mukozasında tespit edilmekle beraber, erken dönemde MCT üzerine etkisi bulunmamaktadır.","PeriodicalId":120468,"journal":{"name":"Turkish Journal of Clinics and Laboratory","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124216815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Robot-Assisted Management of Spontaneous Intramural Left Atrial Hematoma Mimicking an Atrial Mass 模拟心房肿块自发性左心房血肿的机器人辅助治疗

Turkish Journal of Clinics and Laboratory Pub Date : 2023-03-25 DOI: 10.18663/tjcl.1251622

A. Budak, Halil Hüzmeli̇, E. Oğuz, Ahmet Özkara

引用次数: 1

Multidisciplinary Differences in Approaches to Patients Undergoing Breast Examination and Evaluation of Collaborations 乳房检查方法的多学科差异和合作评估

Turkish Journal of Clinics and Laboratory Pub Date : 2023-03-23 DOI: 10.18663/tjcl.1250083

Özgür Albuz, D. Dülger, Gonca Çabuk, Feray Aydin

{"title":"Multidisciplinary Differences in Approaches to Patients Undergoing Breast Examination and Evaluation of Collaborations","authors":"Özgür Albuz, D. Dülger, Gonca Çabuk, Feray Aydin","doi":"10.18663/tjcl.1250083","DOIUrl":"https://doi.org/10.18663/tjcl.1250083","url":null,"abstract":"Amaç: Bu çalışmanın amacı meme muayenesi için hastaneye başvuran hastaların polikliniklerini ve bu uygulamalar sonrasındaki tanı sürecini incelemektir. İkincil amacı da meme kanseri tanısı için genel cerrahi (GC) poliklinikleri ile diğer genel cerrahi dışı kliniklerin karşılaştırılmasıdır.\u0000Gereç ve Yöntemler: Hastanemizin 1 Ocak 2015-15 Haziran 2019 tarihleri arasında genel cerrahi(GC), Dahiliye (IM), Kadın Hastalıkları ve Doğum (OG) polikliniklerine başvuran hastalar retrospektif olarak incelendi. Sürekli değişkenler ortalama ve standart sapma olarak rapor edilirken, kategorik nominal değişkenler toplam popülasyonun yüzdesi olarak ifade edildi.\u0000Bulgular: 1 Ocak 2015-15 Haziran 2019 tarihleri arasında meme muayenesi için gerekli olan toplam mamografi sayısı 7998'dir. Bunların 1769'u Gc, 456'sı IM ve 5773'ü OG poliklinikleridir. Yaş ortalaması Gc'de 48±2,3, IM'de 48±6,7, OG polikliniklerinde 47±3,9 idi (p>0,05). Malign meme vaka sayılarının dağılımı sırasıyla GC: 43, OG: 21, IM: 5 şeklindedir. Toplamda 69 meme kanseri teşhisi konulmuştur. Klinik hakimiyet açısından genel cerrahi kliniği meme kanseri koymada en etkili klinik olarak ortaya çıkmıştır [AOR: 0,34 (0,2-0,54) (P <0,001)]. Mamografi BIRADS 4 ve 5 olan hastalarda malignite riski BIRADS 0-1-2-3 olanlara göre daha yüksekti [AOR: 0,81 (0,72-0,9) (P <0,001)].\u0000Sonuç: Özellikle maligniteyi ilgilendiren meme hastalıklarının tanısında en önemli mihenk taşının klinikler arası işbirliği ile yapılan fizik muayene, anamnez ve görüntüleme teknikleri olduğuna inanıyoruz.","PeriodicalId":120468,"journal":{"name":"Turkish Journal of Clinics and Laboratory","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127629399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of COX 1-2 Inhibitors on Prevention of Rocuronium Injection Pain: Controlled, Randomised, Double Blind Study COX 1-2抑制剂对预防罗库溴铵注射疼痛的作用:对照、随机、双盲研究

Turkish Journal of Clinics and Laboratory Pub Date : 2023-03-23 DOI: 10.18663/tjcl.1166599

Mehmet ŞAHAP, Handan GÜLEÇ, Esra ÖZAYAR, Özlem ÖZDEMİR, Merve KACAN, Aysun KURTAY, Eyüp HORASANLI, Abdulkadir BUT

{"title":"Effects of COX 1-2 Inhibitors on Prevention of Rocuronium Injection Pain: Controlled, Randomised, Double Blind Study","authors":"Mehmet ŞAHAP, Handan GÜLEÇ, Esra ÖZAYAR, Özlem ÖZDEMİR, Merve KACAN, Aysun KURTAY, Eyüp HORASANLI, Abdulkadir BUT","doi":"10.18663/tjcl.1166599","DOIUrl":"https://doi.org/10.18663/tjcl.1166599","url":null,"abstract":"Aim: Rocuronium bromide is a painful agent during induction of general anaesthesia. The aim of the study is to investigate the effects of Cyclooxygenase (COX) inhibitors as a resque agent against the rocuronium pain. Material and Methods: Sixty patients of either sex scheduled for under general anesthesia were enrolled in this study. Patients were allocated into two groups (Group 1: Dexkethoprofen group, Group 2: Control group). Pain was evaluated by during rocuronium injection, patients were scored by a scale showed below. 0; No movement response to injection, 1; Mild movement response to injection, 2; Hand withdrawal response to injection, 3; Arm withdrawal response to injection. We also evaluated the pain with 2 questions when the patient was in the recovery room. Question 1. What was the last feeling before you fall into sleep? and question 2. Did you feel any pain on your hand during medication injection for anesthesia? Results: There were differences between the groups in terms of total pain score for example in group 1 there were 16 (53%) patients who did not make any movement during rocuronium injection while there were 22 (73%) patients in group 2.There was significant difference in injection rocuronium bromide pain between group 1: dexkethoprofen group, Group 2: control group in terms of the answer to the second question. Patients felt less pain than the control group. In the second question, 16% in group 2 stated that they felt pain, while this rate was observed as 3% in group 1. Conclusion: The effect of cox inhibitors on rocuronium pain was seen in our study but control group is also effective in reducing pain in vascular width.","PeriodicalId":120468,"journal":{"name":"Turkish Journal of Clinics and Laboratory","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136166053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0