发布求助
文献互助 智能选刊 最新文献

Current Breast Cancer Reports最新文献

筛选
英文 中文
Moving Towards Targeted Therapies for Triple-Negative Breast Cancer. 向三阴性乳腺癌靶向治疗迈进。
IF 1
Current Breast Cancer Reports Pub Date : 2021-09-01 Epub Date: 2021-05-04 DOI: 10.1007/s12609-021-00416-0
Jodi A Kagihara, Elena Shagisultanova, Anosheh Afghahi, Jennifer R Diamond
{"title":"Moving Towards Targeted Therapies for Triple-Negative Breast Cancer.","authors":"Jodi A Kagihara, Elena Shagisultanova, Anosheh Afghahi, Jennifer R Diamond","doi":"10.1007/s12609-021-00416-0","DOIUrl":"10.1007/s12609-021-00416-0","url":null,"abstract":"<p><strong>Purpose of review: </strong>In this review, we discuss targets of interest in Triple-negative breast cancer (TNBC), approved targeted agents and the results of the clinical trials that led to their approval. Additionally, we review ongoing clinical trials evaluating the use of novel targeted agents in the treatment of TNBC.</p><p><strong>Recent findings: </strong>TNBC accounts for 15-20% of all breast cancer cases and is associated with worse clinical outcomes. Patients have a higher risk of metastatic recurrence and inferior overall survival compared to other breast cancer subtypes. Cytotoxic chemotherapy has historically been the mainstay of treatment for TNBC. In recent years, we have seen a surge in clinical trials investigating the use of targeted agents in TNBC and now have approval for targeted therapies in select patients. Inhibitors of PARP (olaparib and talazoparib), PD-L1 (atezolizumab) and an antibody drug conjugate targeting Trop-2 (sacituzumab govitecan-hziy) are now approved for the use in select groups of patients with TNBC.</p><p><strong>Summary: </strong>Various novel targeted agents as monotherapy, dual targeted combinations, and chemotherapy combinations are currently under investigation. The results are promising and may significantly improve patient outcomes in TNBC.</p>","PeriodicalId":10769,"journal":{"name":"Current Breast Cancer Reports","volume":"13 3","pages":"216-226"},"PeriodicalIF":1.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386298/pdf/nihms-1713830.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39364290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical Risk Reduction, Breast Cancer and Childbearing 手术风险降低、乳腺癌症和生育
IF 0.9
Current Breast Cancer Reports Pub Date : 2021-07-27 DOI: 10.1007/s12609-021-00424-0
C. Weltz, E. Port
{"title":"Surgical Risk Reduction, Breast Cancer and Childbearing","authors":"C. Weltz, E. Port","doi":"10.1007/s12609-021-00424-0","DOIUrl":"https://doi.org/10.1007/s12609-021-00424-0","url":null,"abstract":"","PeriodicalId":10769,"journal":{"name":"Current Breast Cancer Reports","volume":"13 1","pages":"113 - 118"},"PeriodicalIF":0.9,"publicationDate":"2021-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12609-021-00424-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49029780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oncologic Anthropology: An Interdisciplinary Approach to Understanding the Association Between Genetically Defined African Ancestry and Susceptibility for Triple Negative Breast Cancer 肿瘤人类学:一种跨学科的方法来理解遗传上确定的非洲血统与三阴性乳腺癌易感性之间的关系
IF 0.9
Current Breast Cancer Reports Pub Date : 2021-07-18 DOI: 10.1007/s12609-021-00426-y
M. Davis, L. Newman
{"title":"Oncologic Anthropology: An Interdisciplinary Approach to Understanding the Association Between Genetically Defined African Ancestry and Susceptibility for Triple Negative Breast Cancer","authors":"M. Davis, L. Newman","doi":"10.1007/s12609-021-00426-y","DOIUrl":"https://doi.org/10.1007/s12609-021-00426-y","url":null,"abstract":"","PeriodicalId":10769,"journal":{"name":"Current Breast Cancer Reports","volume":"13 1","pages":"247 - 258"},"PeriodicalIF":0.9,"publicationDate":"2021-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12609-021-00426-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44160971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Correction to: Updates in Genetic Testing Guidelines for Breast Cancer Susceptibility Genes: a Change in the Paradigm 更正：乳腺癌症易感性基因基因检测指南的更新：范式的改变
IF 0.9
Current Breast Cancer Reports Pub Date : 2021-07-17 DOI: 10.1007/s12609-021-00425-z
L. Gonzalez, L. Kruper
{"title":"Correction to: Updates in Genetic Testing Guidelines for Breast Cancer Susceptibility Genes: a Change in the Paradigm","authors":"L. Gonzalez, L. Kruper","doi":"10.1007/s12609-021-00425-z","DOIUrl":"https://doi.org/10.1007/s12609-021-00425-z","url":null,"abstract":"","PeriodicalId":10769,"journal":{"name":"Current Breast Cancer Reports","volume":"13 1","pages":"414 - 414"},"PeriodicalIF":0.9,"publicationDate":"2021-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48726565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Screening Mammography in Addressing Disparities in Breast Cancer Diagnosis, Treatment, and Outcomes 乳房x光筛查在解决乳腺癌诊断、治疗和结果差异中的作用
IF 0.9
Current Breast Cancer Reports Pub Date : 2021-07-13 DOI: 10.1007/s12609-021-00427-x
Kimberly M M Isakov, L. Newman, Kemi T Babagbemi
{"title":"The Role of Screening Mammography in Addressing Disparities in Breast Cancer Diagnosis, Treatment, and Outcomes","authors":"Kimberly M M Isakov, L. Newman, Kemi T Babagbemi","doi":"10.1007/s12609-021-00427-x","DOIUrl":"https://doi.org/10.1007/s12609-021-00427-x","url":null,"abstract":"","PeriodicalId":10769,"journal":{"name":"Current Breast Cancer Reports","volume":"13 1","pages":"259 - 267"},"PeriodicalIF":0.9,"publicationDate":"2021-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44468725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Clinical Trials and Breast Cancer Disparities 临床试验和乳腺癌差异
IF 0.9
Current Breast Cancer Reports Pub Date : 2021-06-30 DOI: 10.1007/s12609-021-00422-2
Vivian J. Bea, E. Taiwo, O. Balogun, L. Newman
{"title":"Clinical Trials and Breast Cancer Disparities","authors":"Vivian J. Bea, E. Taiwo, O. Balogun, L. Newman","doi":"10.1007/s12609-021-00422-2","DOIUrl":"https://doi.org/10.1007/s12609-021-00422-2","url":null,"abstract":"","PeriodicalId":10769,"journal":{"name":"Current Breast Cancer Reports","volume":"13 1","pages":"186-196"},"PeriodicalIF":0.9,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12609-021-00422-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46870901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Automated Breast Ultrasound: Technical Aspects, Impact on Breast Screening, and Future Perspectives 自动乳房超声:技术方面，对乳房筛查的影响，以及未来的展望
IF 0.9
Current Breast Cancer Reports Pub Date : 2021-06-23 DOI: 10.1007/s12609-021-00423-1
I. Allajbeu, S. Hickman, N. Payne, P. Moyle, K. Taylor, N. Sharma, F. Gilbert
{"title":"Automated Breast Ultrasound: Technical Aspects, Impact on Breast Screening, and Future Perspectives","authors":"I. Allajbeu, S. Hickman, N. Payne, P. Moyle, K. Taylor, N. Sharma, F. Gilbert","doi":"10.1007/s12609-021-00423-1","DOIUrl":"https://doi.org/10.1007/s12609-021-00423-1","url":null,"abstract":"","PeriodicalId":10769,"journal":{"name":"Current Breast Cancer Reports","volume":"13 1","pages":"141 - 150"},"PeriodicalIF":0.9,"publicationDate":"2021-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12609-021-00423-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46445189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
De-escalation of Systemic Therapy for Early-Stage, Node-Negative Her2+ and Triple-Negative Breast Cancer 早期，淋巴结阴性Her2+和三阴性乳腺癌的全身治疗降级
IF 0.9
Current Breast Cancer Reports Pub Date : 2021-06-14 DOI: 10.1007/s12609-021-00421-3
L. Gonzalez, J. Mortimer, L. Kruper
{"title":"De-escalation of Systemic Therapy for Early-Stage, Node-Negative Her2+ and Triple-Negative Breast Cancer","authors":"L. Gonzalez, J. Mortimer, L. Kruper","doi":"10.1007/s12609-021-00421-3","DOIUrl":"https://doi.org/10.1007/s12609-021-00421-3","url":null,"abstract":"","PeriodicalId":10769,"journal":{"name":"Current Breast Cancer Reports","volume":"13 1","pages":"151 - 156"},"PeriodicalIF":0.9,"publicationDate":"2021-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12609-021-00421-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47091358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Trials of Immunotherapy in Triple Negative Breast Cancer 三阴性乳腺癌的免疫治疗试验
IF 0.9
Current Breast Cancer Reports Pub Date : 2021-06-13 DOI: 10.1007/s12609-021-00418-y
O. Gumusay, C. Wabl, H. Rugo
{"title":"Trials of Immunotherapy in Triple Negative Breast Cancer","authors":"O. Gumusay, C. Wabl, H. Rugo","doi":"10.1007/s12609-021-00418-y","DOIUrl":"https://doi.org/10.1007/s12609-021-00418-y","url":null,"abstract":"","PeriodicalId":10769,"journal":{"name":"Current Breast Cancer Reports","volume":"13 1","pages":"171 - 185"},"PeriodicalIF":0.9,"publicationDate":"2021-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12609-021-00418-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44537418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Fertility Preservation and Breast Cancer 保留生育能力与癌症
IF 0.9
Current Breast Cancer Reports Pub Date : 2021-06-03 DOI: 10.1007/s12609-021-00420-4
Erin E. Roesch, H. Moore
{"title":"Fertility Preservation and Breast Cancer","authors":"Erin E. Roesch, H. Moore","doi":"10.1007/s12609-021-00420-4","DOIUrl":"https://doi.org/10.1007/s12609-021-00420-4","url":null,"abstract":"","PeriodicalId":10769,"journal":{"name":"Current Breast Cancer Reports","volume":"13 1","pages":"197-207"},"PeriodicalIF":0.9,"publicationDate":"2021-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12609-021-00420-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48512278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
首页 上一页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信