Clinical and experimental obstetrics & gynecology最新文献_第10页

Potential of ultrasound in the evaluation of acute appendicitis during pregnancy: a systematic review and meta-analysis 超声在评估妊娠期急性阑尾炎中的潜力：系统综述和荟萃分析

IF 0.2 4区医学

Clinical and experimental obstetrics & gynecology Pub Date : 2022-01-12 DOI: 10.31083/j.ceog4901015

Yunlong Li, Shikuan Li

{"title":"Potential of ultrasound in the evaluation of acute appendicitis during pregnancy: a systematic review and meta-analysis","authors":"Yunlong Li, Shikuan Li","doi":"10.31083/j.ceog4901015","DOIUrl":"https://doi.org/10.31083/j.ceog4901015","url":null,"abstract":"Objective: To assess the accuracy of ultrasound in diagnosing acute appendicitis in pregnant women. Mechanism: The National Library of Medicine (MEDLINE, 1990–2020), Excerpta Medica Database (EMBASE,1946–2020) and the Cochrane Controlled Trials Register (CENTRAL)were used to extract articles that were published in English. A total of five studies involving 521 patients were selected. The DerSimonian and Laird random-effects model and Quality Assessment Tool for Diagnostic Accuracy (QUADAS-2) were used to analyze the data. Findings in brief: We identified 140 related articles and included 5 articles enrolling 521 patients. The values obtained using ultrasound for appendicitis during pregnancy were sensitivity of 0.62 (95% Confidence interval (CI): 0.43–0.78), the specificity of 0.91 (95% CI: 0.74–0.97), and the Positive Likelihood Ratio of 7.0 (95% CI: 2.5–19.7), the Negative Likelihood Ratio of 0.41 (95% CI: 0.27–0.63) and the Diagnostic Odds Ratio of 17 (95% CI : 6–49). Conclusion: Ultrasound had medium-level sensitivity and high specificity for the diagnosis of appendicitis in pregnant women.","PeriodicalId":10312,"journal":{"name":"Clinical and experimental obstetrics & gynecology","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43327405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A retrospective comparative analysis of systemic inflammatory response after laparoscopic, vaginal, and abdominal hysterectomy 腹腔镜、阴道和腹部子宫切除术后全身炎症反应的回顾性比较分析

IF 0.2 4区医学

Clinical and experimental obstetrics & gynecology Pub Date : 2022-01-11 DOI: 10.31083/j.ceog4901010

H. Kim, H. Cho, S. Jeong, Sung-taek Park, Sung-Ho Park

{"title":"A retrospective comparative analysis of systemic inflammatory response after laparoscopic, vaginal, and abdominal hysterectomy","authors":"H. Kim, H. Cho, S. Jeong, Sung-taek Park, Sung-Ho Park","doi":"10.31083/j.ceog4901010","DOIUrl":"https://doi.org/10.31083/j.ceog4901010","url":null,"abstract":"Background: Lymphocyte to neutrophil ratio (NLR) is a rapid and simple marker for systemic inflammation and stress after major surgery. In this study, we aimed to compare NLR changes according to surgical methods of hysterectomy. Methods: A retrospective chart review for all patients who underwent hysterectomy for benign uterine disease from 2016 to 2020 was performed. A total of 1549 women were assigned to total laparoscopic hysterectomy (TLH) (n = 419), vaginal hysterectomy (VH) (n = 608), and total abdominal hysterectomy (TAH) (n = 522) groups. Patient characteristics, surgical outcomes, and NLR changes were compared among women who underwent TLH, VH, and TAH. Results: Preoperative mean NLR was similar among three groups (p = 0.056). However, mean NLR on postoperative day 1 (p < 0.0001) and day 3 (p = 0.011) was significantly lower in TLH group than others. Also, mean NLR change on postoperative day 1 was significantly lesser in TLH group than others (1.9 in TLH vs. 5.4 in VH vs. 4.7 in TAH; p < 0.0001). Mean NLR change on postoperative day 3 was greater in TAH group than others, although there were no statistically significant differences (0.2 in TLH vs. 0.3 in VH vs. 0.7 in TAH; p = 0.354). Multivariate analysis revealed that massive NLR change (>5.0) on postoperative day 1 was significantly associated with types of hysterectomy (p < 0.0001). Conclusion: Our data showed that acute NLR change was lesser in TLH group comparing to VH and TAH group, which suggests that TLH might be associated with less systemic inflammation and tissue trauma after surgery.","PeriodicalId":10312,"journal":{"name":"Clinical and experimental obstetrics & gynecology","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43768096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Long term use of oral contraceptives comprising synthetic estrogens induces an excessive breast cancer risk in BRCA mutation carrier women: a meta-analysis 长期使用含有合成雌激素的口服避孕药会导致BRCA突变携带者患癌症的风险过高：一项荟萃分析

IF 0.2 4区医学

Clinical and experimental obstetrics & gynecology Pub Date : 2022-01-11 DOI: 10.31083/j.ceog4901009

Hongling Peng, Xiaorong Qi, Qiao Wang

{"title":"Long term use of oral contraceptives comprising synthetic estrogens induces an excessive breast cancer risk in BRCA mutation carrier women: a meta-analysis","authors":"Hongling Peng, Xiaorong Qi, Qiao Wang","doi":"10.31083/j.ceog4901009","DOIUrl":"https://doi.org/10.31083/j.ceog4901009","url":null,"abstract":"Background: The relationship between oral contraceptive (OC) use and breast cancer risk is highly debated. Recent publications support a slight increase in overall breast cancer risk among OC user women, in particular among the current users. Women with inherited BRCA1 (Breast cancer type 1) or BRCA2 (Breast cancer type 2) gene mutations are at increased risk of breast and ovarian cancers, which is often mistakenly attributed to their elevated endogenous estrogen levels. The aim of presented meta-analysis was to assess the effects of OC use on breast cancer risk in BRCA mutation carrier women with minimal bias.Methods: A systematic search strategy was used to identify relevant studies, Stata (version 15) was used for meta-analysis. Results: Individual datasets from 13 studies totaling 20,202 patients were analyzed. The combined results showed no significant increase in risk of breast cancer in BRCA mutation carriers who had ever used oral contraceptive (HR = 1.09, 95% CI: 0.71–1.69 among BRCA1 mutation carriers and HR = 1.19, 95% CI: 0.73–1.95 among BRCA2 mutation carriers, respectively). However, in correlation with long-term (>5 years) OC users, the breast cancer risk was significantly increased in both BRCA1 mutation carriers (HR = 1.39, 95% CI: 1.19–1.60) and BRCA1 mutation carriers (HR = 1.61, 95% CI: 1.25–1.96). Conclusion: The presented results indicate that in BRCA mutation carriers women who have defective liganded activation of estrogen receptors (ERs), the use of synthetic estrogens means an additive factor for ER deregulation further increasing the risk for breast cancer. Long term OC use in BRCA mutation carriers results in a significantly increased risk for breast cancer by exhausting the compensatory genome defending process.","PeriodicalId":10312,"journal":{"name":"Clinical and experimental obstetrics & gynecology","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45291565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors influencing parental pregnancy decision-making due to fetuses with non-syndromic orofacial clefts: a study of Chinese couples 影响无综合征性口面裂胎儿父母妊娠决策的因素:对中国夫妇的研究

IF 0.2 4区医学

Clinical and experimental obstetrics & gynecology Pub Date : 2022-01-11 DOI: 10.31083/j.ceog4901008

Huanhuan Ding, Weizeng Zheng, Xinfen Xu, Baohua Li

{"title":"Factors influencing parental pregnancy decision-making due to fetuses with non-syndromic orofacial clefts: a study of Chinese couples","authors":"Huanhuan Ding, Weizeng Zheng, Xinfen Xu, Baohua Li","doi":"10.31083/j.ceog4901008","DOIUrl":"https://doi.org/10.31083/j.ceog4901008","url":null,"abstract":"Background: When a fetus is diagnosed with facial deformities, most Chinese couples choose to terminate the pregnancy. However, these couples commonly regret their decision after the termination of the pregnancy, display a heavier degree of grief, and these feelings persist for a long time. The purpose of this study was to investigate factors that influence parental pregnancy decisions regarding fetuses diagnosed with a non-syndromic orofacial cleft (NSOFC), and to provide the preliminary basis for a formulation of interview outlines useful in further qualitative research in this area. Methods: We collected medical records of 400 couples from the obstetrical units of a women’s hospital in China whose fetuses were diagnosed with Orofacial clefts (OFCs) from January 2013 to July 2019. After excluding those records reporting chromosomal or other abnormalities, 311 cases were included in this study. After univariate analysis, factors that may have affected the parental pregnancy decision were analyzed using binary classification regression analysis. Results: Among the 311 couples, 71.7% (223/311) decided to terminate the pregnancy, whereas 28.3% (88/311) decided to continue. The registered residence, family history of NSOFC, maternal high-risk factors that may lead to the fetus suffering from NSOFC, maternal age, paternal age, doctor’s suggestion, prenatal diagnosis, and first diagnosed gestational week all influenced pregnancy decision makings (p< 0.05). Among these, the registered residence, family history of NSOFC, maternal high-risk factors, maternal age, prenatal diagnosis, and first diagnosed gestational week substantially affected the parental pregnancy decision. Discussion: The couples with registered residence in rural areas, no family history of NSOFC, no maternal high-risk factors, younger maternal age, younger gestational age at first diagnosis are at greater relative risk of pregnancy termination. Prenatal diagnosis is a protective factor.","PeriodicalId":10312,"journal":{"name":"Clinical and experimental obstetrics & gynecology","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45559556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of the COVID-19 pandemic on the policies and practices of delivery facilities in Japan COVID-19大流行对日本配送设施政策和做法的影响

IF 0.2 4区医学

Clinical and experimental obstetrics & gynecology Pub Date : 2022-01-10 DOI: 10.31083/j.ceog4901006

Y. Ebina, Mizuki Takeuchi, Maya Nakamura

{"title":"Impact of the COVID-19 pandemic on the policies and practices of delivery facilities in Japan","authors":"Y. Ebina, Mizuki Takeuchi, Maya Nakamura","doi":"10.31083/j.ceog4901006","DOIUrl":"https://doi.org/10.31083/j.ceog4901006","url":null,"abstract":"Background: To clarify the impact of the COVID-19 pandemic on the policies and practices of delivery facilities in Japan from April 2020 to March 2021. Methods: We conducted an online survey of midwives working in obstetric wards nationwide between May 15, 2021, and July 31, 2021. We analyzed the 376 valid responses. Results: With the COVID-19 pandemic, most facilities have barred or partially restricted families and other visitors from being present (patient companions) in outpatient clinics, prenatal classes, during delivery, inpatient care, and inpatient visits. These changes were implemented nationwide, regardless of regional differences in the pandemic state of COVID-19. Meanwhile, by facility classification, prenatal classes, companion at birth, and inpatient visits were more likely to be canceled at perinatal centers than at clinics. The acceptance of “satogaeri deliveries” (a custom in Japan where pregnant women return to their natal homes for labor and childbirth) was partially restricted to about 40% of facilities, although this rate was lower in the four Kanto prefectures (Tokyo, Kanagawa, Saitama, and Chiba). Conclusions: With the COVID-19 pandemic, the differences in Japan’s policies and practices of delivery facilities were attributed more to the role played by facilities in the regional perinatal system than to regional pandemic status. © 2022 S.O.G. CANADA Inc.. All rights reserved.","PeriodicalId":10312,"journal":{"name":"Clinical and experimental obstetrics & gynecology","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49169075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

COUP-TFI deletion affects angiogenesis and apoptosis related gene expression in mouse placenta: results of an explorative study COUP-TFI缺失影响小鼠胎盘血管生成和凋亡相关基因表达的探索性研究结果

IF 0.2 4区医学

Clinical and experimental obstetrics & gynecology Pub Date : 2022-01-10 DOI: 10.31083/j.ceog4901007

L. Viola, S. Marzinotto, M. Bertacchi, A. Londero, M. Orsaria, S. Bertozzi, L. Driul, C. di Loreto, M. Studer, L. Mariuzzi, A. Fruscalzo

{"title":"COUP-TFI deletion affects angiogenesis and apoptosis related gene expression in mouse placenta: results of an explorative study","authors":"L. Viola, S. Marzinotto, M. Bertacchi, A. Londero, M. Orsaria, S. Bertozzi, L. Driul, C. di Loreto, M. Studer, L. Mariuzzi, A. Fruscalzo","doi":"10.31083/j.ceog4901007","DOIUrl":"https://doi.org/10.31083/j.ceog4901007","url":null,"abstract":"Background: Chicken Ovalbumin Upstream Promoter-Transcription Factor I (COUP-TFI) is a member of the steroid/thyroid nuclear receptor superfamily. The aim of this study was to investigate whether absence of this gene affects placental development and fetal growth in a COUP-TFI knockout mouse model. Methods: Placentas of COUP-TFI-knockout (COUP-TFI KO) and wild-type (WT) were collected at 18.5 days post-coitum. The expression level of the following genes known to be involved in different key molecular pathways was evaluated: BCL2Associated X (Bax) and B-cell lymphoma 2 (Bcl-2) (apoptosis), p21, p53 andα subunit of inhibin (INHA) (proliferation and apoptosis), vascular endothelial growth factor A (VEGF-A), placental growth factor (PlGF), hypoxia-inducible factor 1-alpha (HIF1α), Fms related receptor tyrosine kinase 1 (Flt-1), and endoglin (ENG) (angiogenesis). Mouse litter weight at birth was also assessed. Results: RT-qPCR analysis showed increased mRNA expression of VEGF-A and Bax in placental tissue of COUP-TFI KO mice compared to WT mice. We also found a loss in the positive correlation between Bcl-2 and INHA, p21 and ENG, as well as HIF1α and Flt-1 mRNA expression in COUP-TFI mutants. Finally, KO mice were lighter than WT littermates (respectively, the mean weight of COUP-TFI KOmice was 1.3 grams,± 0.13, compared to 1.6 g,± 0.14 ofWTmice, p< 0.05). Conclusions: Our results show that COUP-TFI deletion is associated with a lower birth weight in mice and increased placental transcript expression of pro-apoptotic Bax and pro-angiogenetic VEGF-A genes.","PeriodicalId":10312,"journal":{"name":"Clinical and experimental obstetrics & gynecology","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48681537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Analyzing the detrimental effects of female chronic hepatitis B virus DNA on ovarian reserve function and results of in vitro fertilization 女性慢性乙型肝炎病毒DNA对卵巢储备功能及体外受精结果的影响分析

IF 0.2 4区医学

Clinical and experimental obstetrics & gynecology Pub Date : 2022-01-07 DOI: 10.31083/j.ceog4901004

Liu Liu, Hua Liang, J. Yang, Fujin Shen, Wei Li

{"title":"Analyzing the detrimental effects of female chronic hepatitis B virus DNA on ovarian reserve function and results of in vitro fertilization","authors":"Liu Liu, Hua Liang, J. Yang, Fujin Shen, Wei Li","doi":"10.31083/j.ceog4901004","DOIUrl":"https://doi.org/10.31083/j.ceog4901004","url":null,"abstract":"Background: To evaluate both the impact of hepatitis B virus (HBV)-DNA copies in women with HBV infection on the ovarian reserve function and outcomes of in vitro fertilization (IVF).Methods: We conducted a retrospective study on a total of 9927 couples undergoing their first IVF cycle. After filtering, 1570 couples (546 HBV-seropositive women and 1024 HBV-seronegative women whose partners were HBV-seronegative) failed to meet inclusion criteria. According to the HBV-DNA titers in serum, the HBV-seropositive group was divided into three groups: DNA-high copy group (n = 139), DNA-low copy group (n = 241), and DNA-negative group (n = 166). All patients underwent controlled ovarian hyperstimulation using the long downregulation protocol followed by IVF. Results: Compared with the HBV-negative group, HBV-positive women with high DNA copy exhibited lower antral follicle count (AFC) (11.9 ± 4.3 vs 13.3± 3.2), lower number of oocyte retrieved (9.2± 5.7 vs 13.1± 6.1), larger proportion of AFC<8 (7.9% vs 3.1%) and anti-mullerian hormone (AMH) <2 μg/L (8.6% vs 4.3%). Both high-DNA copy and low-DNA copy groups exhibited a lower fertilization rate (70.9% and 72.5% vs 75.1%), lower high-grade embryo rate (51.5% and 53.8% vs 56.9%), lower implantation rate (31.3% and 32.7% vs 38.5%), lower clinical pregnancy rate (40.3% and 42.3% vs 49.6% per cycle with OR; 45.5% and 48.8% vs 56.8% per cycle with ET) than the HBV-negative group. Moreover, a higher early abortion rate (19.6% and 15.7% vs 7.1%) was observed in the above two groups. Conclusion: HBV-DNA may have a negative effect on women’s ovarian reserve function which in turn results in poor fertilization rate, clinical pregnancy rate and high early abortion rate in IVF treatment.","PeriodicalId":10312,"journal":{"name":"Clinical and experimental obstetrics & gynecology","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46211861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Isolated tubal torsion associated with hydrosalpinx 孤立性输卵管扭转伴输卵管积水

IF 0.2 4区医学

Clinical and experimental obstetrics & gynecology Pub Date : 2022-01-07 DOI: 10.31083/j.ceog4901005

E. Tamburacı

引用次数: 0

A novel complementary method for ultrasonographic screening of deep endometriosis: a case series of 5 patients diagnosed with transvaginal strain elastography 超声筛查深层子宫内膜异位症的一种新的补充方法：经阴道应变弹性成像诊断的5例病例系列

IF 0.2 4区医学

Clinical and experimental obstetrics & gynecology Pub Date : 2022-01-06 DOI: 10.31083/j.ceog4901002

G. Szabó, I. Madár, János Rigó Jr, N. Dobó, N. Ács, A. Bokor

引用次数: 0

The effects of cosmetic care on body image, social avoidance and distress in young Chinese breast cancer patients receiving chemotherapy 美容护理对中国年轻乳腺癌化疗患者身体形象、社会回避和焦虑的影响

IF 0.2 4区医学

Clinical and experimental obstetrics & gynecology Pub Date : 2022-01-06 DOI: 10.31083/j.ceog4901003

Shengqun Hou, Zhen-qi Lu, Jiajia Qiu, Xiaoju Zhang, Jialing Huang, Yun Li, Cuixia Fu

{"title":"The effects of cosmetic care on body image, social avoidance and distress in young Chinese breast cancer patients receiving chemotherapy","authors":"Shengqun Hou, Zhen-qi Lu, Jiajia Qiu, Xiaoju Zhang, Jialing Huang, Yun Li, Cuixia Fu","doi":"10.31083/j.ceog4901003","DOIUrl":"https://doi.org/10.31083/j.ceog4901003","url":null,"abstract":"Background: This study aimed to explore the effects of cosmetic care on body image (BI), and social avoidance and distress (SAD) in young Chinese breast cancer patients, aged 18–40 years old, receiving adjuvant chemotherapy. Methods: This was a 2-arm quasiexperimental study based on a single-center. A convenience sample of 76 hospitalized young female breast cancer patients, stage 0-III breast cancer diagnosis was recruited. The control group received usual care, while cosmetic care was added to the intervention group. The primary outcomes were BI and SAD accompanying chemotherapy, and the secondary outcome was the appearance satisfaction. It was registered at Clinical Trials.gov, no. NCT04733482. Results: There were significant differences in patients’ body image, and social avoidance and distress scores from the pre-discharge (T0) to at the end of the chemotherapy cycle (T2) between two groups (P < 0.05). However, the intervention did not significantly change the appearance satisfaction at T2 (P > 0.05). Logistic regression suggested there were no confounding demographic factors influencing the intervention. Conclusions: The present study indicated that cosmetic care improved BI and reduced SAD in young Chinese breast cancer patients during adjuvant chemotherapy. However, a randomized study should be undertaken to confirm our results.","PeriodicalId":10312,"journal":{"name":"Clinical and experimental obstetrics & gynecology","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49138652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0