Revista Brasileira de Reumatologia (English Edition)最新文献

{"title":"Determinants of quality of life in Paget's disease of bone","authors":"Gláucio Ricardo Werner de Castro ,&nbsp;Silvania Ana Fernandes de Castro ,&nbsp;Ivanio Alves Pereira ,&nbsp;Adriana Fontes Zimmermann ,&nbsp;Maria Amazile Toscano ,&nbsp;Fabricio Souza Neves ,&nbsp;Maria Aparecida Scottini ,&nbsp;Juliane Paupitz ,&nbsp;Julia Salvan da Rosa ,&nbsp;Ziliani Buss ,&nbsp;Tânia Silvia Fröde","doi":"10.1016/j.rbre.2017.06.002","DOIUrl":"10.1016/j.rbre.2017.06.002","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate the parameters associated with quality of life in patients with Paget's disease of bone.</p></div><div><h3>Methods</h3><p>Patients with Paget's disease of bone were evaluated with SF-36 and WHOQOL-bref questionnaires. Patients with other diseases that could cause significant impairment of their quality of life were excluded. We searched for correlations between the results and: age, time from diagnosis, type of involvement, pain related to Paget's disease of bone, limitation to daily activities, deformities, bone specific alkaline phosphatase, the extent of involvement and treatment.</p></div><div><h3>Results</h3><p>Fifty patients were included. Results of the SF-36 total score and its domains, physical and mental health, were significantly correlated with bone pain and deformities. Marital status was significantly correlated with the SF-36 total score and Mental Health Domain. BAP levels and disease extension were significantly correlated to SF-36 Physical Health Domain. After multivariate analysis, the only parameters that remained significantly associated with the SF-36 total score and to its Mental Health and Physical Health Domains were pain and marital status.</p><p>The WHOQOL-bref total score was significantly associated with pain, physical impairment and deformities. WHOQOL-bref Domain 1 (physical) score was significantly associated with marital status, pain and deformities, while Domain 2 (psychological) score was associated with marital status, physical impairment and kind of involvement. After multivariate analysis, the presence of pain, deformities, and marital status were significantly associated with results of the WHOQOL-bref total score and its Domain 1. WHOQOL-bref domain 2 results were significantly predicted by pain and marital status.</p></div><div><h3>Conclusion</h3><p>The main disease-related factor associated with SF-36 results in Paget's disease of bone patients was bone pain, while bone pain and deformities were associated with WHOQOL-bref.</p></div>","PeriodicalId":101096,"journal":{"name":"Revista Brasileira de Reumatologia (English Edition)","volume":"57 6","pages":"Pages 566-573"},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbre.2017.06.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35406035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scientific people named in the classification of vasculitis","authors":"Gokhan Sargin,&nbsp;Taskin Senturk","doi":"10.1016/j.rbre.2016.06.002","DOIUrl":"10.1016/j.rbre.2016.06.002","url":null,"abstract":"<div><p>The first International Chapel Hill Consensus Conference was held in 1994. There have been suggestions about the nomenclature of systemic vasculitis. Important categories were added to the classification of vasculitis, and many changes were made for disease names in the second Chapel Hill Consensus Conference 2012, which were not included in the Chapel Hill Consensus Conference 1994. The new nomenclature was introduced instead of being referred to by many names such as Churg-Strauss and Wegener”s. New categories such as Behçet”s and Cogan etc. were also added. These people are honored by the classification. They contribute to science through their case studies, scientific articles, and observations. This article reviews only eponyms present in the current classification of vasculitis. The aim of this paper is to give information about scientists mentioned in the classification of vasculitis.</p></div>","PeriodicalId":101096,"journal":{"name":"Revista Brasileira de Reumatologia (English Edition)","volume":"57 6","pages":"Pages 605-609"},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbre.2016.06.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35637368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relapsing polychondritis and lymphocytic meningitis with varied neurological symptoms","authors":"Renata Dal-Prá Ducci ,&nbsp;Francisco Manoel Branco Germiniani ,&nbsp;Letícia Elizabeth Augustin Czecko ,&nbsp;Eduardo S. Paiva ,&nbsp;Hélio Afonso Ghizoni Teive","doi":"10.1016/j.rbre.2016.02.005","DOIUrl":"10.1016/j.rbre.2016.02.005","url":null,"abstract":"","PeriodicalId":101096,"journal":{"name":"Revista Brasileira de Reumatologia (English Edition)","volume":"57 6","pages":"Pages 623-625"},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbre.2016.02.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35637850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hepcidin-25 gives an indication of the therapeutic effectiveness of tocilizumab in rheumatoid arthritis – Relationship between disease activity of rheumatoid arthritis and anemia","authors":"Satoshi Suzuki ,&nbsp;Souichiro Nakano ,&nbsp;Seiichiro Ando ,&nbsp;Ran Matsudaira ,&nbsp;Yoshinori Kanai ,&nbsp;Kenjiro Yamanaka ,&nbsp;Yoshinari Takasaki","doi":"10.1016/j.rbre.2016.09.004","DOIUrl":"10.1016/j.rbre.2016.09.004","url":null,"abstract":"","PeriodicalId":101096,"journal":{"name":"Revista Brasileira de Reumatologia (English Edition)","volume":"57 6","pages":"Pages 637-640"},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbre.2016.09.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35637856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic plasma exchange in rheumatic diseases: a university hospital experience","authors":"Juan Pablo Córdoba ,&nbsp;Carolina Larrarte ,&nbsp;Cristina Estrada ,&nbsp;Daniel G. Fernández-Ávila","doi":"10.1016/j.rbre.2017.01.003","DOIUrl":"10.1016/j.rbre.2017.01.003","url":null,"abstract":"<div><h3>Introduction</h3><p>Each day, evidence accumulates related to the use of therapeutic plasma exchange (TPE) in patients with rheumatic diseases. San Ignacio University Hospital has recorded all of the TPE sessions performed by the institution's apheresis group.</p></div><div><h3>Objective</h3><p>To describe the TPE experience of patients with rheumatologic diseases in a hospital setting.</p></div><div><h3>Methods</h3><p>Descriptive, observational, retrospective analysis. This study included analyses of the TPE sessions that were performed in patients with rheumatic diseases from November 2009 to November 2013.</p></div><div><h3>Results</h3><p>The apheresis group performed 136 sessions in 27 patients. The mean patient age was 43 years (SD 18.5), and 59.3% of the patients were female. Regarding the diagnosis, the most frequents ones where: ANCA-associated vasculitis followed by systemic lupus erythematosus and catastrophic antiphospholipid syndrome. The average number of sessions per patient was 5 (SD 1.8), and the average plasma exchange per patient was 1.3 plasma volume replacement units. The most used replacement solution was frozen fresh plasma (FFP; 63.2% of the sessions). Of all the sessions, 4.4% presented complications, and the majority of the complications were related to vascular access. Fifteen patients required renal replacement therapy (RRT) secondary to the same cause that created the need for TPE, 3 patients required RRT due to causes other than the TPE diagnostic intervention and 1 patient had undergone chronic dialysis.</p></div><div><h3>Conclusions</h3><p>TPE is a therapeutic alternative that is needed for the management of patients with rheumatic diseases with renal involvement and those who are refractory to conventional management. Our clinical results were in agreement with the global literature.</p></div>","PeriodicalId":101096,"journal":{"name":"Revista Brasileira de Reumatologia (English Edition)","volume":"57 5","pages":"Pages 397-402"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbre.2017.01.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35514780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of multiparity on bone mineral density, evaluated with bone turnover markers","authors":"Hasan Terzi ,&nbsp;Rabia Terzi ,&nbsp;Ebru Kale ,&nbsp;Ahmet Kale","doi":"10.1016/j.rbre.2015.09.002","DOIUrl":"10.1016/j.rbre.2015.09.002","url":null,"abstract":"<div><h3>Objective</h3><p>Our aim was to investigate the effect of parity on osteoporosis by evaluating bone mineral density, markers of bone turn-over and other factors that are effective in osteoporosis in multiparous (five deliveries or more) and nulliparous women in the post-menopausal period.</p></div><div><h3>Methods</h3><p>A total of 91 multiparous (five deliveries or more) and 31 nulliparous postmenopausal women were included in this study. All patients were interviewed on sociodemographic characteristics, gynecologic history, personal habits, levels of physical activity, and life-long intake of calcium. Bone mineral density was measured at lumbar (L1–4) and femoral neck regions with Dexa.</p></div><div><h3>Results</h3><p>The mean age of multiparous women was 58.79<!--> <!-->±<!--> <!-->7.85 years, and the mean age of nulliparous women was 55.84<!--> <!-->±<!--> <!-->7.51. The femoral BMD was 0.94<!--> <!-->±<!--> <!-->0.16 and lumbar BMD 1.01<!--> <!-->±<!--> <!-->0.16 in multiparous women, femoral BMD was 0.99<!--> <!-->±<!--> <!-->0.16 and lumbar BMD 1.07<!--> <!-->±<!--> <!-->0.14 in nulliparous women. There were no statistical differences between the femoral and lumbar <em>T</em> scores and BMD values of the two groups. Lumbar <em>T</em> scores and lumbar BMD showed a decrease with increasing total duration of breast-feeding in multiparous women. The independent risk factors for osteoporosis in the regression analysis of multiparous women were found to be the duration of menopause and body weight of 65<!--> <!-->kg and less.</p></div><div><h3>Conclusion</h3><p>There is no difference between the bone mineral densities of multiparous and nulliparous women. Females with lower body-weight and longer duration of menopause should be followed-up more carefully for development of osteoporosis.</p></div>","PeriodicalId":101096,"journal":{"name":"Revista Brasileira de Reumatologia (English Edition)","volume":"57 5","pages":"Pages 371-377"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbre.2015.09.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35612293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Topographic MRI evaluation of the sacroiliac joints in patients with axial spondyloarthritis","authors":"Laís Uyeda Aivazoglou ,&nbsp;Orlando Rondan Zotti ,&nbsp;Marcelo de Medeiros Pinheiro ,&nbsp;Moacir Ribeiro de Castro Junior ,&nbsp;Andrea Puchnick ,&nbsp;Artur da Rocha Corrêa Fernandes ,&nbsp;Eloy de Ávila Fernandes","doi":"10.1016/j.rbre.2016.09.002","DOIUrl":"10.1016/j.rbre.2016.09.002","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate the imaging features of spondyloarthritis in magnetic resonance imaging (MRI) of the sacroiliac (SI) joint and topography (in thirds) and affected margin, considering that this issue is rarely addressed in the literature.</p></div><div><h3>Methods</h3><p>A cross-sectional study evaluating MRI (1.5<!--> <!-->T) of SI in 16 patients with axial spondyloarthritis, for the presence of acute (subchondral bone edema, enthesitis, synovitis and capsulitis) and chronic (erosions, subchondral bone sclerosis, bony bridges, and fatty infiltration) changes, performed by two blinded radiologists. MRI findings were correlated with clinical data, including age, duration of disease, medications, HLA-B27, BASDAI, ASDAS-ESR and ASDAS-CRP, BASMI, BASFI, and mSASSS.</p></div><div><h3>Results</h3><p>Bone edema pattern and erosions were predominant in the upper third of SI (<em>p</em> <!-->=<!--> <!-->0.050 and <em>p</em> <!-->=<!--> <!-->0.0014, respectively). There was a correlation between disease duration and structural changes by affected third (<em>p</em> <!-->=<!--> <!-->0.028–0.037), as well as between the presence of bone bridges with BASMI (<em>p</em> <!-->=<!--> <!-->0.028) and mSASSS (<em>p</em> <!-->=<!--> <!-->0.014). Patients with osteitis in the lower third showed higher values for ASDAS (ESR: <em>p</em> <!-->=<!--> <!-->0.011 and PCR: <em>p</em> <!-->=<!--> <!-->0.017).</p></div><div><h3>Conclusion</h3><p>Chronic inflammatory changes and the pattern of bone edema predominated in the upper third of SI, but a simultaneous involvement of middle or lower thirds of the joint was also noted. The location of involvement in the upper third of SI is insufficient to differentiate between degeneration and inflammation.</p></div>","PeriodicalId":101096,"journal":{"name":"Revista Brasileira de Reumatologia (English Edition)","volume":"57 5","pages":"Pages 378-384"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbre.2016.09.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35514777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between cellular expression of complement regulatory proteins with depletion and repopulation of B-lymphocytes in peripheral blood of patients with rheumatoid arthritis treated with rituximab","authors":"Daniela Viecceli ,&nbsp;Mariana Pires Garcia ,&nbsp;Laiana Schneider ,&nbsp;Ana Paula Alegretti ,&nbsp;Cristiano Kohler Silva ,&nbsp;André Lucas Ribeiro ,&nbsp;Claiton Viegas Brenol ,&nbsp;Ricardo Machado Xavier","doi":"10.1016/j.rbre.2016.09.007","DOIUrl":"10.1016/j.rbre.2016.09.007","url":null,"abstract":"<div><h3>Objectives</h3><p>To correlate the basal expression of complement regulatory proteins (CRPs) CD55, CD59, CD35, and CD46 in B-lymphocytes from the peripheral blood of a cohort of 10 patients with rheumatoid arthritis (RA) initiating treatment with rituximab (RTX) with depletion and time repopulation of such cells.</p></div><div><h3>Methods</h3><p>Ten patients with RA received two infusions of 1<!--> <!-->g of RTX with an interval of 14 days. Immunophenotypic analysis for the detection of CD55, CD59, CD35, and CD46 on B-lymphocytes was carried out immediately before the first infusion. The population of B-lymphocytes was analyzed by means of basal CD19 expression and after 1, 2, and 6 months after the infusion of RTX, and then quarterly until clinical relapse. Depletion of B-lymphocytes in peripheral blood was defined as a CD19 expression &lt;0.005<!--> <!-->×<!--> <!-->109/L.</p></div><div><h3>Results</h3><p>Ten women with a median of 49 years and a baseline DAS28<!--> <!-->=<!--> <!-->5.6 were evaluated; 9 were seropositive for rheumatoid factor. Five patients showed a repopulation of B-lymphocytes after 2 months, and the other five after 6 months. There was a correlation between the basal expression of CD46 and the time of repopulation (correlation coefficient<!--> <!-->=<!--> <!-->−0.733, <em>p</em> <!-->=<!--> <!-->0.0016). A similar trend was observed with CD35, but without statistical significance (correction coefficient<!--> <!-->=<!--> <!-->−0.522, <em>p</em> <!-->=<!--> <!-->0.12).</p></div><div><h3>Conclusion</h3><p>The increased CD46 expression was predictive of a faster repopulation of B-lymphocytes in patients treated with RTX. Studies involving a larger number of patients will be needed to confirm the utility of basal expression of CRPs as a predictor of clinical response.</p></div>","PeriodicalId":101096,"journal":{"name":"Revista Brasileira de Reumatologia (English Edition)","volume":"57 5","pages":"Pages 385-391"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbre.2016.09.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35514778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improvement of nailfold capillary microangiopathy after immunosuppressant therapy in a child with clinically amyopathic juvenile dermatomyositis","authors":"Lúcia Maria Arruda Campos ,&nbsp;Adriana M.E. Sallum ,&nbsp;Cintia Z. Camargo ,&nbsp;Luís Eduardo C. Andrade ,&nbsp;Cristiane Kayser","doi":"10.1016/j.rbre.2016.05.002","DOIUrl":"10.1016/j.rbre.2016.05.002","url":null,"abstract":"","PeriodicalId":101096,"journal":{"name":"Revista Brasileira de Reumatologia (English Edition)","volume":"57 5","pages":"Pages 487-490"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbre.2016.05.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35515224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum to “Effects of the use of growth hormone in children, adolescents with juvenile idiopathic arthritis: a systematic review” (Rev Bras Reumatol. 2017;57(2):100-106)","authors":"Renan Bazuco Frittoli ,&nbsp;Barbara Sugui Longhi ,&nbsp;Amanda Meireles Silva ,&nbsp;Antônio de Azevedo Barros Filho ,&nbsp;Maria Ângela Reis de Góes Monteiro ,&nbsp;Simone Appenzeller","doi":"10.1016/j.rbre.2017.09.003","DOIUrl":"10.1016/j.rbre.2017.09.003","url":null,"abstract":"","PeriodicalId":101096,"journal":{"name":"Revista Brasileira de Reumatologia (English Edition)","volume":"57 5","pages":"Page 500"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbre.2017.09.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35515227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}