APS JournalPub Date : 1994-03-01DOI: 10.1016/S1058-9139(05)80238-4
Manfred Zimmermann, Thomas Herdegen
{"title":"Rebuttal to the comments of Dr. Bullitt and professor Basbaum","authors":"Manfred Zimmermann, Thomas Herdegen","doi":"10.1016/S1058-9139(05)80238-4","DOIUrl":"10.1016/S1058-9139(05)80238-4","url":null,"abstract":"","PeriodicalId":100112,"journal":{"name":"APS Journal","volume":"3 1","pages":"Pages 60-62"},"PeriodicalIF":0.0,"publicationDate":"1994-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1058-9139(05)80238-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76468657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
APS JournalPub Date : 1993-12-01DOI: 10.1016/S1058-9139(05)80260-8
Donald A. Simone
{"title":"Mediators of spinal hyperexcitability and hyperalgesia","authors":"Donald A. Simone","doi":"10.1016/S1058-9139(05)80260-8","DOIUrl":"10.1016/S1058-9139(05)80260-8","url":null,"abstract":"","PeriodicalId":100112,"journal":{"name":"APS Journal","volume":"2 4","pages":"Pages 283-286"},"PeriodicalIF":0.0,"publicationDate":"1993-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1058-9139(05)80260-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89411865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
APS JournalPub Date : 1993-12-01DOI: 10.1016/S1058-9139(05)80250-5
Peter J. Jannetta
{"title":"Rebuttal of commentaries concerning the focus article","authors":"Peter J. Jannetta","doi":"10.1016/S1058-9139(05)80250-5","DOIUrl":"10.1016/S1058-9139(05)80250-5","url":null,"abstract":"","PeriodicalId":100112,"journal":{"name":"APS Journal","volume":"2 4","pages":"Pages 237-238"},"PeriodicalIF":0.0,"publicationDate":"1993-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1058-9139(05)80250-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82999261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
APS JournalPub Date : 1993-12-01DOI: 10.1016/S1058-9139(05)80255-4
Patrick D. Wall
{"title":"In what language do nerve cells communicate?","authors":"Patrick D. Wall","doi":"10.1016/S1058-9139(05)80255-4","DOIUrl":"10.1016/S1058-9139(05)80255-4","url":null,"abstract":"","PeriodicalId":100112,"journal":{"name":"APS Journal","volume":"2 4","pages":"Pages 259-261"},"PeriodicalIF":0.0,"publicationDate":"1993-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1058-9139(05)80255-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73993568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
APS JournalPub Date : 1993-12-01DOI: 10.1016/S1058-9139(05)80257-8
George L. Wilcox
{"title":"Spinal mediators of nociceptive neurotransmission and hyperalgesia","authors":"George L. Wilcox","doi":"10.1016/S1058-9139(05)80257-8","DOIUrl":"10.1016/S1058-9139(05)80257-8","url":null,"abstract":"<div><p>The synaptic mechanisms of nociception, hyperalgesia, allodynia, opioid tolerance, and neuropathic pain in the spinal cord dorsal horn are explored. The characteristics of the transmitters conveying excitation and the mechanisms that can enhance synaptic efficacy in the spinal nociceptive system after prolonged stimulation are examined, and a possible sequence of events that could contribute to progressive development, after intense or pathologic stimulation, of enhanced neuronal responsiveness from initial synaptic plasticity and hyperalgesia to subsequent neurotoxicity and neuropathic pain is described. The progression includes neurokinins and excitatory amino acids as neurotransmitters acting at neurokinins and excitatory amino acids receptors and evoking the production of nitric oxide by spinal interneurons. Finally, the importance of spinal blood flow as an affected function and an effective participant is discussed.</p></div>","PeriodicalId":100112,"journal":{"name":"APS Journal","volume":"2 4","pages":"Pages 265-275"},"PeriodicalIF":0.0,"publicationDate":"1993-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1058-9139(05)80257-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90365761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
APS JournalPub Date : 1993-12-01DOI: 10.1016/S1058-9139(05)80247-5
Sean Mullan
{"title":"Vascular compression is the cause of trigeminal neuralgia","authors":"Sean Mullan","doi":"10.1016/S1058-9139(05)80247-5","DOIUrl":"10.1016/S1058-9139(05)80247-5","url":null,"abstract":"","PeriodicalId":100112,"journal":{"name":"APS Journal","volume":"2 4","pages":"Pages 228-230"},"PeriodicalIF":0.0,"publicationDate":"1993-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1058-9139(05)80247-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87310411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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