Fragmented QRS as a predictor of hypertensive crisis in patients with newly diagnosed essential hypertension: 4-year follow-up data.

IF 1.1 4区医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Herz Pub Date : 2023-12-01 Epub Date: 2023-06-27 DOI:10.1007/s00059-023-05194-2

Emine Altuntas, Sükrü Cetın

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引用次数: 0

Abstract

Background: Hypertensive crisis (HC) is a life-threatening condition in patients with hypertension (HT). However, there is no electrocardiography (ECG) marker that can predict which hypertensive patient may develop HC. The fragmented QRS (fQRS) complex is an important prognostic marker in ECG that might be predict cardiovascular events and mortality. Our study aimed to investigate whether fQRS can predict the development of HC in patients with HT, within 4 years of follow-up.

Methods: Newly diagnosed patients with essential HT were recruited for the study from an outpatient clinic. The patients were divided into two groups according to the presence of HC: HC (+) and HC (-). During follow-up, the relationship between fQRS and HC was evaluated.

Results: The study group included 504 patients with newly diagnosed HT. During the follow-up period, HC occurred in 98 of the patients. In 57 (11.30%) patients, fQRS was observed on ECG; fQRS was detected in the ECG of 19 (19.38%) of the HC (+) patients (p = 0.008). The results of multivariate logistic regression analysis showed that fQRS (p < 0.001) was as independent predictor for HC development. Kaplan-Meier analysis further demonstrated that the presence of fQRS affects the development of hypertensive urgency in hypertensive patients (log-rank p < 0.001).

Conclusion: In patients with newly diagnosed HT, the presence of fQRS was found to be an independent predictor of HC.

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碎片化QRS作为新诊断原发性高血压患者高血压危象的预测因子:4年随访数据

背景:高血压危象(hypertension crisis, HC)是高血压(HT)患者中一种危及生命的疾病。然而，没有心电图(ECG)标记可以预测哪些高血压患者可能发展为HC。碎片化QRS (fQRS)复合体是心电图中一项重要的预后指标，可用于预测心血管事件和死亡率。我们的研究旨在探讨fQRS能否在随访4年内预测HT患者HC的发展。方法:从门诊招募新诊断的原发性HT患者进行研究。根据HC的存在情况将患者分为HC(+)和HC(-)两组。在随访中，评估fQRS与HC的关系。结果:研究组纳入504例新诊断的HT患者。随访期间，98例患者发生HC。57例(11.30%)患者心电图出现fQRS;HC(+)患者心电图检测到fQRS 19例(19.38%)(p = 0.008)。多因素logistic回归分析结果显示fQRS (p )在新诊断的HT患者中，fQRS的存在是HC的独立预测因子。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Herz 医学-心血管系统

CiteScore

3.00

自引率

5.90%

发文量

审稿时长

4-8 weeks

期刊介绍： Herz is the high-level journal for further education for all physicians interested in cardiology. The individual issues of the journal each deal with specific topics and comprise review articles in English and German written by competent and esteemed authors. They provide up-to-date and comprehensive information concerning the speciality dealt with in the issue. Due to the fact that all relevant aspects of the pertinent topic of an issue are considered, an overview of the current status and progress in cardiology is presented. Reviews and original articles round off the spectrum of information provided.