Prevalence and risk factors of self-reported financial toxicity in cancer survivors: A systematic review and meta-analyses.

IF 1.5 4区医学 Q4 PSYCHOLOGY, SOCIAL

Journal of Psychosocial Oncology Pub Date : 2023-01-01 DOI:10.1080/07347332.2022.2142877

Hua Jiang, Jianxia Lyu, Wenxuan Mou, Luxi Jiang, Yu Zeng, Ying Liu, Aiping Hu, Qinghua Jiang

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引用次数: 2

Abstract

Background: Similar to the side effects of cancer treatment, financial toxicity (FT) can affect the quality of life of patients, which has attracted increasing attention in the field of oncology. Despite the fact that the estimated prevalence and risk factors of FT are widely reported, these results have not been synthesized.

Objectives: This review is aimed to systematically assess the prevalence and risk factors of self-reported FT.

Design: Systematic review and meta-analyses.

Data sources: A computer search of English literature was conducted using databases of PubMed, EMBASE, Web of Science, PsycINFO, and CINAHL, and reference lists of the qualified articles were also included between January 2010 and September 2021. Observational studies that reported the prevalence or risk factors of FT using subjective measures were included.

Methods: The systematic review was guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. The risk of bias was assessed by the NIH observational cohort and cross-sectional study quality assessment tool. The data were extracted by two reviewers and listed in a descriptive table for meta-analyses.

Results: In the 22 studies available for meta-analyses of pooled prevalence of FT, the result was estimated to be 45% (95% CI: 38% to 53%, I² = 97.3%, P < 0.001) based on a random-effects model. The pooled analysis identified 9 potential risk factors of FT (7 in β and 8 in OR): low income (OR = 2.48, 95% CI: 1.72 to 3.24, I² = 3.1%, P < 0.001), greater annual OOP (β = -4.26, 95% CI: -6.95 to -1.57, I² = 0%, P = 0.002), younger age (OR = 2.05, 95% CI: 1.56 to 2.54, I² = 0%, P < 0.001), no private insurance (OR = 1.69, 95% CI: 1.02 to 2.37, I² = 0%, P < 0.001), unmarried (OR = 1.10, 95% CI: 0.95 to 1.25, I² = 53,3%, P < 0.001), nonwhite (OR = 1.59, 95% CI: 1.33 to 1.85, I² = 0%, P < 0.001), advanced cancer (β = -4.74, 95% CI: -6.90 to -2.57, I² = 0%, P < 0.001), unemployed (β = -2.90, 95% CI: -5.71 to -0.63, I² = 75,7%, P < 0.001), more recent diagnosis (OR = 1.31, 95% CI: 1.04 to 1.57, I² = 0%, P < 0.001).

Conclusion: This systematic review reported a pooled prevalence of self-reported FT of 45%. Low income, greater annual OOP (Out of pocket), younger age, unmarried, unemployed, nonwhite, no private insurance, advanced cancer, and more recent diagnosis constituted risk factors for self-reported FT. The research on risk factors for FT can provide a theoretical basis for medical staff to evaluate and intervene in the FT among cancer survivors.

查看原文本刊更多论文

癌症幸存者自我报告的财务毒性的患病率和危险因素:系统回顾和荟萃分析。

背景:与癌症治疗的副作用类似，金融毒性(financial toxicity, FT)也会影响患者的生活质量，越来越受到肿瘤学领域的关注。尽管FT的估计患病率和危险因素被广泛报道，但这些结果尚未被综合。目的:本综述旨在系统地评估自我报告ft的患病率和危险因素。设计:系统综述和荟萃分析。数据来源:计算机检索PubMed、EMBASE、Web of Science、PsycINFO、CINAHL等数据库的英文文献，并纳入2010年1月至2021年9月间符合条件的文章参考文献列表。使用主观测量报告FT患病率或危险因素的观察性研究被纳入。方法:采用系统评价和荟萃分析首选报告项目(PRISMA)声明进行系统评价。偏倚风险通过NIH观察队列和横断面研究质量评估工具进行评估。数据由两位审稿人提取，并列在描述表中进行meta分析。22个研究可供荟萃分析的结果:汇集英国《金融时报》,结果是估计为45% (95% CI: 38%至53%,I2 = 97.3%, P 2 = 3.1%, P 2 = 0%, P = 0.002),年轻的年龄(或= 2.05,95%置信区间CI: 1.56 - 2.54, I2 = 0%, P 2 = 0%, P 2 = 53岁3%,P 2 = 0%, P 2 = 0%, P = 75, 7%, P 2 = 0%, P结论:这个系统回顾报告汇集了自我报告的英国《金融时报》的患病率为45%。收入低、年自费高、年龄小、未婚、无业、非白人、无私人保险、癌症晚期、诊断时间较晚构成自报FT的危险因素。对FT危险因素的研究可以为医务人员评估和干预癌症幸存者的FT提供理论依据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Psychosocial Oncology PSYCHOLOGY, SOCIAL-

CiteScore

4.20

自引率

0.00%

发文量

期刊介绍： Here is your single source of integrated information on providing the best psychosocial care possible from the knowledge available from many disciplines.The Journal of Psychosocial Oncology is an essential source for up-to-date clinical and research material geared toward health professionals who provide psychosocial services to cancer patients, their families, and their caregivers. The journal—the first interdisciplinary resource of its kind—is in its third decade of examining exploratory and hypothesis testing and presenting program evaluation research on critical areas, including: the stigma of cancer; employment and personal problems facing cancer patients; patient education.