Endometrial cancer.

IF 76.9 1区医学 Q1 MEDICINE, GENERAL & INTERNAL

Nature Reviews Disease Primers Pub Date : 2021-12-09 DOI:10.1038/s41572-021-00324-8

Vicky Makker, Helen MacKay, Isabelle Ray-Coquard, Douglas A Levine, Shannon N Westin, Daisuke Aoki, Ana Oaknin

引用次数: 0

Abstract

Although endometrial cancer management remains challenging, a deeper understanding of the genetic diversity as well as the drivers of the various pathogenic states of this disease has led to development of divergent management approaches in an effort to improve therapeutic precision in this complex malignancy. This comprehensive review provides an update on the epidemiology, pathophysiology, diagnosis and molecular classification, recent advancements in disease management, as well as important patient quality-of-life considerations and emerging developments in the rapidly evolving therapeutic landscape of endometrial cancers.

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子宫内膜癌

尽管子宫内膜癌的治疗仍然充满挑战，但随着对该疾病遗传多样性和各种致病状态驱动因素的深入了解，人们开发出了不同的治疗方法，以提高这种复杂恶性肿瘤的治疗精度。这篇综合综述介绍了流行病学、病理生理学、诊断和分子分类的最新进展、疾病管理的最新进展、患者生活质量的重要考虑因素以及快速发展的子宫内膜癌治疗领域的新进展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Disease Primers Medicine-General Medicine

CiteScore

76.70

自引率

0.20%

发文量

期刊介绍： Nature Reviews Disease Primers, a part of the Nature Reviews journal portfolio, features sections on epidemiology, mechanisms, diagnosis, management, and patient quality of life. The editorial team commissions top researchers — comprising basic scientists and clinical researchers — to write the Primers, which are designed for use by early career researchers, medical students and principal investigators. Each Primer concludes with an Outlook section, highlighting future research directions. Covered medical specialties include Cardiology, Dermatology, Ear, Nose and Throat, Emergency Medicine, Endocrinology, Gastroenterology, Genetic Conditions, Gynaecology and Obstetrics, Hepatology, Haematology, Infectious Diseases, Maxillofacial and Oral Medicine, Nephrology, Neurology, Nutrition, Oncology, Ophthalmology, Orthopaedics, Psychiatry, Respiratory Medicine, Rheumatology, Sleep Medicine, and Urology.