[Pediatric genital lichen sclerosus: a case series of 11 girls].

IF 1 4区医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Anales Del Sistema Sanitario De Navarra Pub Date : 2022-11-18 DOI:10.23938/ASSN.1014

Jorge Aróstegui Aguilar, Leire Loidi, Ingrid Hiltun, Mónica Larrea, Lourdes Cascante, Juan Ignacio Yanguas

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引用次数: 0

Abstract

Background: Genital lichen sclerosus decreases the quality of life of women; 10-15% of cases occur in prepubertal girls.

Methods: Retrospective and descriptive study on the characteristics of girls diagnosed with genital lichen sclerosus at the Hospital Universitario de Navarra (Pamplona, Spain) between 2019 and 2022.

Results: Eleven girls aged between 4 and 14 year-old were diagnosed. Frequently, diagnostic delays were up to two years after the appearance of the lesions; the girl with a four-year delay showed a significant vulvar architectural alteration. All cases showed the typical sclerotic lesions on the genital area, and two of them also on the back. While six patients were asymptomatic, the rest reported pruritus and/or pain. Treatment with high/very high potency topical cortico-steroids achieved a good partial response, without complete remission of the lesions.

Conclusion: Early diagnosis of genital lichen sclerosus is key to start early treatment, avoiding ireversible genital structural alteration.

Abstract Image

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[小儿生殖器硬化性地衣:11例女孩]。

背景:生殖器硬化地衣降低女性的生活质量;10-15%的病例发生在青春期前的女孩。方法:回顾性和描述性研究2019年至2022年在西班牙潘普洛纳纳瓦拉大学医院诊断为生殖器硬化性地衣的女孩的特征。结果:11名年龄在4 ~ 14岁的女孩被确诊。通常，诊断延误长达两年的病变出现后;延迟4年的女孩外阴结构明显改变。所有病例均表现为生殖器区典型的硬化性病变，其中2例也出现在背部。6例患者无症状，其余报告瘙痒和/或疼痛。高/非常高效力的局部皮质类固醇治疗取得了良好的部分反应，没有完全缓解病变。结论:早期诊断是早期治疗的关键，避免不可逆转的生殖器结构改变。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Anales Del Sistema Sanitario De Navarra 医学-公共卫生、环境卫生与职业卫生

CiteScore

1.30

自引率

30.00%

发文量

审稿时长

>12 weeks

期刊介绍： La revista Anales del Sistema Sanitario de Navarra es una revista de contenido médico sanitario de carácter generalista. En ella tienen cabida artículos referidos a temas de salud/enfermedad en general, salud pública, administración y gestión sanitaria y Atención Primaria de salud.