Community-associated Clostridioides difficile infection in a general hospital from Argentina

IF 2.5 3区 生物学 Q3 MICROBIOLOGY
Barbara Fox, Valentina Ricci, Silvina Bergese, Pablo Striebeck, Ana Schneider, María Alejandra Berger, María Ivana Maldonado, Liliana Fernandez-Canigia
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引用次数: 0

Abstract

Toxin-producing Clostridioides difficile infection (CDI) is the leading cause of hospital-acquired diarrhea. However, it is now recognized as a cause of diarrhea in the community. This single-center study aimed to determine the epidemiological origin of CDI cases between January 2014 and December 2019 and to compare demographic characteristics, comorbidities, risk factors, severity, and mortality of community CDI with healthcare facility-associated CDI. There were 52 CDI cases from the community (34.4%). Community patients were significantly younger (53 yo vs. 65 yo), less comorbid (Charlson Index 1.65 vs. 3.98), and less severe (only one case). The main risk factor was the use of antibiotics in the previous 90 days (65%). However, we did not find any known risk factor in 7 patients.

阿根廷一家综合医院的社区相关艰难梭菌感染。
产生毒素的艰难梭菌感染(CDI)是医院获得性腹泻的主要原因。然而,它现在被认为是社区腹泻的一个原因。这项单中心研究旨在确定2014年1月至2019年12月期间CDI病例的流行病学来源,并比较社区CDI与医疗机构相关CDI的人口统计学特征、合并症、风险因素、严重程度和死亡率。社区有52例CDI病例(34.4%)。社区患者明显更年轻(53岁vs.65岁),合并症更少(Charlson指数1.65 vs.3.98),病情更轻(只有一例)。主要危险因素是前90天使用抗生素(65%)。然而,我们在7名患者中没有发现任何已知的风险因素。
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来源期刊
Anaerobe
Anaerobe 生物-微生物学
CiteScore
5.20
自引率
8.70%
发文量
137
审稿时长
76 days
期刊介绍: Anaerobe is essential reading for those who wish to remain at the forefront of discoveries relating to life processes of strictly anaerobes. The journal is multi-disciplinary, and provides a unique forum for those investigating anaerobic organisms that cause infections in humans and animals, as well as anaerobes that play roles in microbiomes or environmental processes. Anaerobe publishes reviews, mini reviews, original research articles, notes and case reports. Relevant topics fall into the broad categories of anaerobes in human and animal diseases, anaerobes in the microbiome, anaerobes in the environment, diagnosis of anaerobes in clinical microbiology laboratories, molecular biology, genetics, pathogenesis, toxins and antibiotic susceptibility of anaerobic bacteria.
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