Uveitis including Vogt-Koyanagi-Harada syndrome following inactive covid-19 vaccination: a case series.

IF 2.9 Q1 OPHTHALMOLOGY
Mehrdad Motamed Shariati, Mojtaba Abrishami, Shahin Jahani, Ali Bolouki, Mohamad-Reza Ansari-Astaneh, Seyedeh Maryam Hosseini
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引用次数: 2

Abstract

Background: Currently, large populations have been vaccinated against COVID-19. The whole inactivated Sinopharm COVID-19 vaccine has been the main available COVID-19 vaccine in Iran. Ocular inflammatory reactions have been reported following vaccination. The present case reports aim to introduce four cases of uveitis after the Sinopharm vaccine administration.

Case presentation: Our first reported case is a 38-year-old woman with a positive medical history of inactive ulcerative colitis. Active uveitis had developed following the second dose of the COVID-19 vaccination. The remaining three cases were healthy individuals who developed the first episode of uveitis, after the COVID-19 vaccine administration. Vogt-Koyanagi-Harada syndrome was the final diagnosis in one of the aforementioned cases. All four patients demonstrated favorable responses to corticosteroid treatment.

Conclusion: These observations are in line with incoming reports from all around the world and raise concerns about the possibility of post-vaccination uveitis development, especially in cases with a previous history of auto-immune systemic diseases or inactive uveitis.

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非活性covid-19疫苗接种后葡萄膜炎包括Vogt-Koyanagi-Harada综合征:病例系列
背景:目前,已有大量人群接种了COVID-19疫苗。目前,国药全灭活疫苗是伊朗现有的主要新型冠状病毒疫苗。接种疫苗后有眼部炎症反应的报道。本文报道4例国药疫苗接种后发生葡萄膜炎的病例。病例介绍:我们报告的第一个病例是一位38岁的女性,她有非活动性溃疡性结肠炎的阳性病史。在第二剂COVID-19疫苗接种后出现了活动性葡萄膜炎。其余三例是在接种COVID-19疫苗后出现首次葡萄膜炎发作的健康个体。Vogt-Koyanagi-Harada综合征是上述病例之一的最终诊断。所有4例患者均表现出对皮质类固醇治疗的良好反应。结论:这些观察结果与来自世界各地的最新报告一致,并引起了人们对疫苗接种后葡萄膜炎发展的可能性的关注,特别是在既往有自身免疫性系统性疾病或非活动性葡萄膜炎病史的病例中。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.80
自引率
3.40%
发文量
39
审稿时长
13 weeks
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