{"title":"Hereditary Neuropathy with Liability to Pressure Palsy Presenting as Bilateral Foot Drop.","authors":"İsmail Koç, Güray Koç, Betül Özenç, Zeki Odabaşı","doi":"10.5152/eurasianjmed.2023.21154","DOIUrl":null,"url":null,"abstract":"Hereditary neuropathy with liability to pressure palsy (HNPP) is a rare, autosomal dominant disorder that typically presents with episodic, multifocal neuropathy, and recurrent transient pressure palsies. 1 We report a patient who was misdiagnosed as transverse myelitis suggestive of multiple sclerosis based on acute onset bilateral foot drop. However, detailed history, careful examination, and electroneuromyography (ENMG) were consistent with HNPP. A 22-year-old male developed a sudden onset of weakness in his legs. Imaging of the brain and spine, serum, and cerebrospinal fluid analysis were all normal. Normoactive deep tendon reflexes with acute onset were interpreted as transverse myelitis. He was given methylpredniso-lone, which had no obvious effect. He was then referred to our clinic and we learned that the patient had cross-legged sitting while playing a computer game for hours. He had bilateral ankle and toe dorsiflexion weakness; however, inversion was normal bilaterally. He had hypoesthesia","PeriodicalId":53592,"journal":{"name":"Eurasian Journal of Medicine","volume":null,"pages":null},"PeriodicalIF":0.9000,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081114/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Eurasian Journal of Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5152/eurasianjmed.2023.21154","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Hereditary neuropathy with liability to pressure palsy (HNPP) is a rare, autosomal dominant disorder that typically presents with episodic, multifocal neuropathy, and recurrent transient pressure palsies. 1 We report a patient who was misdiagnosed as transverse myelitis suggestive of multiple sclerosis based on acute onset bilateral foot drop. However, detailed history, careful examination, and electroneuromyography (ENMG) were consistent with HNPP. A 22-year-old male developed a sudden onset of weakness in his legs. Imaging of the brain and spine, serum, and cerebrospinal fluid analysis were all normal. Normoactive deep tendon reflexes with acute onset were interpreted as transverse myelitis. He was given methylpredniso-lone, which had no obvious effect. He was then referred to our clinic and we learned that the patient had cross-legged sitting while playing a computer game for hours. He had bilateral ankle and toe dorsiflexion weakness; however, inversion was normal bilaterally. He had hypoesthesia
期刊介绍:
Eurasian Journal of Medicine (Eurasian J Med) is an international, scientific, open access periodical published by independent, unbiased, and triple-blinded peer-review principles. The journal is the official publication of Atatürk University School of Medicine and published triannually in February, June, and October. The publication language of the journal is English. The aim of the Eurasian Journal of Medicine is to publish original research papers of the highest scientific and clinical value in all medical fields. The Eurasian J Med also includes reviews, editorial short notes and letters to the editor that either as a comment related to recently published articles in our journal or as a case report. The target audience of the journal includes researchers, physicians and healthcare professionals who are interested or working in in all medical disciplines.