A Review of Selected Dental Anomalies With Histologic Features in the Pediatric Patient.

IF 1.3 4区 医学 Q3 PATHOLOGY
Pediatric and Developmental Pathology Pub Date : 2023-11-01 Epub Date: 2023-11-14 DOI:10.1177/10935266231207045
Kathleen M Schultz, Carla R Penner
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引用次数: 0

Abstract

Unique dental conditions in children include odontogenic cysts and tumors, hereditary dental diseases, developmental anomalies, and lesions associated with the eruption of the primary or permanent teeth. Many of these conditions have long lasting effects on the adult dentition in terms of affecting esthetics, function, and overall quality of life. Inherited dental syndromes affect the dental hard tissues specifically the enamel, dentin, and/or cementum in a generalized manner, involving both primary and permanent teeth. These conditions manifest in altered quality or quantity of the hard tissues, leading to fragility, tooth loss and dental diseases such as caries, periapical pathology, and periodontal disease. This category includes amelogenesis imperfecta, dentinogenesis imperfecta, dentin dysplasia, hypophosphatasia, and hypophosphatemia. Developmental defects such as regional odontodysplasia are defined by involvement of the primary and permanent dentition in a localized manner, identified in early childhood. This review will elaborate on the histologic findings in these selected dental conditions with a discussion on clinical and radiographic findings, as well as molecular features wherever appropriate.

儿科患者具有组织学特征的牙齿异常的综述。
儿童独特的牙齿状况包括牙源性囊肿和肿瘤、遗传性牙齿疾病、发育异常以及与乳牙或恒牙的萌出有关的病变。这些情况对成人牙齿的美观、功能和整体生活质量都有长期的影响。遗传性牙综合征影响牙硬组织,特别是牙釉质、牙本质和牙骨质,影响范围广泛,包括乳牙和恒牙。这些情况表现为硬组织的质量或数量的改变,导致脆弱,牙齿脱落和牙齿疾病,如龋齿,根尖周围病理和牙周病。这一类包括无釉发育不全症、牙本质发育不全症、牙本质发育不良、低磷血症和低磷血症。发育缺陷,如局部牙发育不良,是指在儿童早期发现的原发性和永久性牙列局部受累。这篇综述将详细阐述在这些选定的牙齿条件下的组织学发现,并讨论临床和放射学表现,以及适当的分子特征。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.70
自引率
5.30%
发文量
59
审稿时长
6-12 weeks
期刊介绍: The Journal covers the spectrum of disorders of early development (including embryology, placentology, and teratology), gestational and perinatal diseases, and all diseases of childhood. Studies may be in any field of experimental, anatomic, or clinical pathology, including molecular pathology. Case reports are published only if they provide new insights into disease mechanisms or new information.
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