Abstract 1185: PRMT5 inhibition epigenetically regulates DNA damage response pathways in cancer cells and sensitizes to chemotherapy and PARP inhibition

Koichi Ito, Jack Carter, V. Thodima, Youyou Zhang, Monisha Sivakumar, Mu Xu, N. Bhagwat, J. Rager, Jacob Spruance, Lin Zhang, Bruce R Ruggeri, P. Scherle, K. Vaddi
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引用次数: 0
摘要:PRMT5抑制在表观遗传学上调控癌细胞的DNA损伤反应途径,并对化疗和PARP抑制增敏
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