Heterogeneous Catalytic Method for the One-pot Three-component Synthesis of Isoquinolonic Acid Derivatives Catalyzed by a 4Å Molecular Sieves Supported Lanthanum Catalyst

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2022-06-29 DOI:10.3311/ppch.20094

Ágnes Magyar, Zoltán Hell

引用次数: 1

Abstract

Lanthanum supported on 4Å molecular sieves proved to be an efficient heterogeneous catalyst for the one-pot three-component synthesis of 1,2,3,4-tetrahydroisoquinolinone-4-carboxylic acid derivatives from homophthalic anhydride, aromatic aldehydes and an amine component, ammonium acetate or aralkyl amines, with good to excellent yields. The catalyst could be recovered easily and reused without significant loss of its initial activity.

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4Å分子筛负载镧催化剂催化一锅三组分合成异喹啉酸衍生物的非均相催化方法

结果表明，负载在4Å分子筛上的镧是一种高效的非均相催化剂，可由均邻苯二酸酐、芳香族醛和胺类组分乙酸铵或芳烷基胺一锅合成1,2,3,4-四氢异喹啉-4-羧酸衍生物，收率高至优异。该催化剂可以很容易地回收和重复使用，而不会显著损失其初始活性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.