Clinical parameters and bacteriological evaluation of Acess® as a periodontal therapeutic toothpaste: a non-blinded randomized clinical trial

Satoshi Shirakawa, Yuji Matsushima, Yuuki Hayata, Youko Nakano, Momoko Nakata, Tomohito Nakagawa, Y. Nagashima, Masahiko Nikaidou, K. Gomi
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Abstract

: Acess Ⓡ toothpaste includes formulation ingredients (latania, chamomile, and myrrh) and re-portedly improves periodontal disease by exerting gingival convergence and anti-inflammatory effects. Although each of these ingredients has antibacterial effects, the effects of Acess Ⓡ on the oral bacteria remain unknown. The present study was aimed at examining the effects of brushing teeth with Acess Ⓡ on periodontal disease and the oral bacterial population. This was a randomized, open-label, parallel, intergroup trial. Each participant was randomly assigned to receive either Acess Ⓡ or a control tooth paste formulation. Participants brushed their teeth twice daily, once in the morning and once in the evening, for five minutes per session. We then assessed clinical parameters such as gingival index (GI), pocket depth (PD), bleeding on probing (BOP) and plaque control record (PCR), and carried out salivary bacteriological examination at baseline and at two and four weeks post-baseline.
access®牙周治疗牙膏的临床参数和细菌学评价:一项非盲随机临床试验
:访问Ⓡ牙膏含有配方成分(latania,洋甘菊和没药),据报道,通过发挥牙龈收敛和抗炎作用,可以改善牙周病。虽然这些成分都有抗菌作用,但accessⓇ对口腔细菌的影响尚不清楚。本研究旨在探讨使用accessⓇ刷牙对牙周病及口腔细菌群的影响。这是一项随机、开放标签、平行、组间试验。每个参与者被随机分配接受访问Ⓡ或对照牙膏配方。参与者每天刷两次牙,早上一次,晚上一次,每次5分钟。然后我们评估临床参数,如牙龈指数(GI),口袋深度(PD),探查出血(BOP)和菌斑控制记录(PCR),并在基线和基线后2周和4周进行唾液细菌学检查。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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