Nanoneuromedicines for Neurodegenerative Diseases

Ram Singh
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引用次数: 1

Abstract

Neurodegenerative disease is a collective term for a number of diseases that affect the neurons in the human brain. The location of the neuronal loss in the brain leads to the specified disease based on the progression of the clinical symptoms. No drugs are available for complete cure of these diseases. Most of the drugs only slow down the progression of neuronal damage. The combination of drugs with nanotechnology gave a new promising hope for the treatment of neurological disorders. Nanomedicines are extremely useful for safe, effective, target oriented and sustained delivery. Due to their size in nanometer, they possess distinct and improved properties in comparison to their bulk counterpart. The utility of nanomedicines in neurological disorders including neurodegenerative diseases constitutes nanoneuromedicines. In this article, a comprehensive overview of the application of nanoneuromedicines in neurodegenerative diseases such as Alzheimer’s Disease (AD), Parkinson’s Disease (PD) and Amyotrophic Lateral Sclerosis (ALS) is provided.
神经退行性疾病的纳米神经药物
神经退行性疾病是影响人脑神经元的一系列疾病的总称。根据临床症状的进展,神经元丧失在大脑中的位置导致特定的疾病。没有药物可以完全治愈这些疾病。大多数药物只能减缓神经损伤的进展。药物与纳米技术的结合给神经系统疾病的治疗带来了新的希望。纳米药物在安全、有效、靶向和持续给药方面非常有用。由于它们的尺寸以纳米为单位,与它们的体积对应物相比,它们具有独特的和改进的性能。纳米药物在包括神经退行性疾病在内的神经系统疾病中的应用构成了纳米神经药物。本文综述了纳米神经药物在阿尔茨海默病(AD)、帕金森病(PD)和肌萎缩侧索硬化症(ALS)等神经退行性疾病中的应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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