Aeromonas Infections in Patients with Liver Cirrhosis in Japan

Abstract

Aeromonas species are recognized as opportunistic pathogens that cause serious problems in patients with liver cirrhosis (LC). In this article, 25 case reports of Aeromonas infections in patients with LC in Japan are reviewed and summarized. Among the 25 cases, cases of septicemia or skin and soft tissue infections have been relatively well reported. In total, the 1-month mortality rate was 68% (17/25), whereas the overall survival rate was 32% (8/25). In particular, among 16 cases with skin and soft tissue infections, 12 (75%) died within the first 4 days after admission, regardless of the administration of antimicrobial agents and/or lower limb amputation, indicating extremely poor short-term prognosis.