When Appearances Can be Deceiving: Sarcopenia and Obesity Paradox. Unsolved Issues in Critically Ill Surgical Patients

M. Barone
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Abstract

Faced with the complexity of emergency surgery and the aging of the population, it is increasingly common to have to deal with critically ill patients who require intensive care postoperatively. Surgical stress amplifies senescence mechanisms where the organism is called to face the establishment of both early and late pathophysiological mechanisms disrupting homeostasis. In this scenario, sarcopenia represents a prognostic factor with a multifactorial etiology that can lead to fearful complications in the early postoperative period. As an octogenarian adaptation, its multifactorial genesis allows to act and counterbalance the action of concomitant modifiable factors through post-operative optimization strategies. Abstract Article: Frontera R, Barone M, Ippoliti M. When Appearances Can be Deceiving: Sarcopenia and Obesity Paradox. Unsolved Issues in Critically Ill Surgical Patients. 2022;6(3):
当表象具有欺骗性:肌肉减少症和肥胖悖论。外科危重病人未解决的问题
面对急诊手术的复杂性和人口老龄化,需要在术后进行重症监护的危重患者越来越普遍。手术应激放大了衰老机制,生物体需要面对破坏体内平衡的早期和晚期病理生理机制的建立。在这种情况下,肌肉减少症是一个多因素的预后因素,可导致术后早期可怕的并发症。作为一种八十多岁的适应性,其多因素的发生允许通过术后优化策略来作用和抵消伴随的可改变因素的作用。文章摘要:Frontera R, Barone M, Ippoliti M.当表象可以欺骗:肌肉减少和肥胖悖论。外科危重患者未解决的问题[j] . 2022;6(3):
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CiteScore
5.60
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