Collision Tumour of Combined Neuroendocrine and Squamous Cell Carcinoma of Nasal Cavity and Paranasal Sinus- Case Report and Review of Literature.

Q2 Earth and Planetary Sciences

湖泊科学 Pub Date : 2023-12-01 Epub Date: 2023-07-21 DOI:10.1007/s12070-023-04101-9

Vikas Arora, Vishal Yadav, Manisha Aggarwal, Ghanashyam Mandal, Arnab Chakraborty, A K Dewan, Meenakshi Kamboj

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Abstract

Background: There have been many disputes about the definition, diagnosis, therapy, and prognosis of collision tumours.

Case summary: We describe a rare patient with a collision tumour consisting of high-grade neuroendocrine carcinoma (NEC) and squamous cell carcinoma (SCC) in the right nasal cavity and paranasal sinus. She received surgery, concurrent chemoradiotherapy, and then two cycles of palliative chemotherapy. Follow-up at 26 months after diagnosis showed that this patient experienced a complete response with no signs of recurrence or metastasis. A literature review of previous 27 cases diagnosed with collision tumour of NEC and SCC in the head and neck was also undertaken.

Conclusion: It is highly challenging to manage collision tumours because these are two morphologically and etiologically distinct tumours. Well-designed multimodality therapy including surgery and chemoradiotherapy might lead to a long survival in these patients.

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鼻腔及鼻窦神经内分泌与鳞状细胞癌合并碰撞瘤1例报告及文献复习。

背景:关于碰撞瘤的定义、诊断、治疗和预后一直存在诸多争议。病例总结:我们报告一例罕见的右鼻腔及副鼻窦高级别神经内分泌癌(NEC)及鳞状细胞癌(SCC)的碰撞肿瘤。她接受了手术，同步放化疗，然后是两个周期的姑息性化疗。诊断后26个月的随访显示，该患者完全缓解，无复发或转移迹象。对27例诊断为头颈部NEC和SCC碰撞瘤的病例进行文献回顾。结论:碰撞瘤是两种形态和病因不同的肿瘤，其治疗具有很高的挑战性。精心设计的包括手术和放化疗在内的多模式治疗可能会导致这些患者的长期生存。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

湖泊科学 Environmental Science-Water Science and Technology

CiteScore

3.70

自引率

0.00%

发文量

3253

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