Infections à virus respiratoire syncytial et virus para-influenza : prévention et traitement

F Freymuth (Professeur de virologie, biologiste des hôpitaux)
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引用次数: 0

Abstract

Controlling the dissemination to children of the respiratory syncytial virus (RSV) and parainfluenzae virus (PIV) rests mainly on simple hygiene measures such as hand washing and contact precautions. In addition to the nonspecific treatment of bronchiolitis (chest physiotherapy), ribavirin, an antiviral agent active against the RSV and PIV in vitro, is used in clinical practice only by inhalation in severe forms of RSV infection. Anti-RSV immune globulins have been proved effective in preventing RSV infection or its severe forms. The humanized monoclonal antibody palivizumab is used in France in selected patients.

感染病毒呼吸道合胞体病毒副流感:预防和治疗
控制呼吸道合胞病毒(RSV)和副流感病毒(PIV)向儿童传播主要依靠简单的卫生措施,如洗手和接触预防措施。除了毛细支气管炎的非特异性治疗(胸部物理治疗)外,利巴韦林是一种体外抗RSV和PIV的抗病毒药物,在临床实践中仅通过吸入治疗严重形式的RSV感染。抗RSV免疫球蛋白已被证明对预防RSV感染或其严重形式有效。人源化单克隆抗体palvizumab在法国用于选定的患者。
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