Antiplatelet Effect of Leonurine from Leonurus sibiricus

The Chinese Pharmaceutical Journal Pub Date : 2007-09-01 DOI:10.7019/TPJ.200709.0149

Hang-Ching Lin, Sheng-Ming Pan, H. Ding, T. Chou, Wen-liang Chang

引用次数: 10

Abstract

Leonurine (1) was simply isolated from the aerial part of Leonurus sibircus var. albiflora. Their structures were established on the basis of spectral evidence. Leonurine showed a significant inhibited rabbit platelet aggregation induced by thrombin, arachidonic acid, and collagen in vitro with an IC50 of 97.22 μM, 31.03 μM, and 44.48 μM, respectively.

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益母草尿的抗血小板作用

Leonurine(1)是从益母草(Leonurus sibircus var. albiflora)的地上部分简单分离得到的。它们的结构是根据光谱证据确定的。Leonurine对凝血酶、花生四烯酸和胶原诱导的兔血小板聚集有明显的抑制作用，IC50分别为97.22 μM、31.03 μM和44.48 μM。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

The Chinese Pharmaceutical Journal

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