Penetapan Kadar Fe Gluconate dengan Metode Fe Fumarate Secara Spektrofotometri UV-Vis

R. Ismet, Bella Kavalena Raeis, Sriwulan Sriwulan
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Abstract

The human frame requires macroelements and microelements. The system of blood formation is the synthesis of hemoglobin. Iron is a totally crucial microelement and is needed by using the body. one of the iron dietary supplements that may be consumed to save you and deal with iron deficiency is Ferrous Gluconate. Ferrous Fumarate and Ferrous Gluconate have the same function, but there are variations in the analytical method of assay. The purpose of this observation is to validate the method for figuring out the concentration of Fe Gluconate compounds in drug samples, while the approach used is UV-Vis spectrophotometry. approach validation turned into achieved earlier than assaying the pattern. Parameters within the validation technique used include specificity, device suitability, linearity, accuracy, precision, and LOD and LOQ. The consequences of the validation of the analytical approach showed precise results with the RSD acquisition of all test parameters acquired via a fee of < 2%. The values for the quantitation restrict (LOQ) and detection limit (LOD) additionally showed precise consequences, the LOD acquired became 6.920 ppm and the LOQ received changed to 23.067 ppm. in step with the meals and Drug management in 2001, the outcomes of the validation of the analytical approach on this study have met the standards and specifications, because numerous test indicators have met them. so that this method can be utilized in determining the levels of Fe Gluconate. dedication of Fe Gluconate degrees in drug samples obtained consequences with a median cost of 99.770%.
对UV-Vis的光谱分析
人体需要大量元素和微量元素。血液形成系统是血红蛋白的合成。铁是一种至关重要的微量元素,是人体所需要的。葡萄糖酸亚铁是一种可以拯救你并解决缺铁问题的膳食补充剂。富马酸亚铁和葡萄糖酸亚铁具有相同的功能,但在分析方法上有所不同。本实验的目的是验证用紫外-可见分光光度法测定药物样品中葡萄糖酸铁化合物浓度的方法。方法验证比分析模式更早实现。所使用的验证技术中的参数包括特异性、器械适用性、线性度、准确度、精密度、LOD和LOQ。分析方法验证的结果显示,通过< 2%的费用获得的所有测试参数的RSD获取精确的结果。定量限限(LOQ)和检出限(LOD)的值也显示出精确的结果,获得的LOQ变为6.920 ppm,接收的LOQ变为23.067 ppm。与2001年的食品药品管理步调一致,本研究的分析方法验证结果符合标准和规范,因为许多测试指标符合标准和规范。该方法可用于测定葡萄糖酸铁的含量。葡萄糖酸铁度在药物样品中的奉献获得的结果中位数成本为99.770%。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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