Short-term effects of modest salt reduction combined with DASH diet on changing salt eating habits in hypertensive patients with type II diabetes

IF 1.5 4区医学 Q3 PERIPHERAL VASCULAR DISEASE

Clinical and Experimental Hypertension Pub Date : 2022-05-25 DOI:10.1080/10641963.2022.2079666

Dan Chen, Jie Tang, Tao Gong, Lisha Mu, Jing Li, Pi-Ching Yu, Hao Wang, X. Bu, L. Mu, Ying Mei

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引用次数: 1

Abstract

ABSTRACT Objective Excessive salt intake is currently the foremost universal risk factor for controllable chronic disease. This study evaluated the short-term effects of a modest salt intake reduction combined with the Chinese Modified Dietary Approaches to Stop Hypertension (CM-DASH) diet on sodium and potassium intake, mean arterial pressure (MAP), and pulse pressure (PP) in hypertensive patients with type II diabetes. Methods Sixty-one participants were randomized to the intervention group (52% low-sodium salt and DASH) and control group (normal salt and DASH). An 8-week dietary intervention was applied. Daily salt intake, blood pressure (BP), and drug use were recorded every week. Twenty-four-hour urine, casual urine, and blood samples were measured at baseline, the 4th week, and the end of the intervention. Results Fifty-nine patients (25 men) completed the entire study. Sodium intake decreased by 1259.66 (792.76, 1726.56)/705.80 (149.21, 1262.39) mg/day after 4 weeks (intervention: P < .001; control: P = .015). Potassium intake increased by 641.14 (73.31, 1208.96)/43.43 (−259.66, 346.53) mg/day (intervention: P = .028); MAP decreased by 9.06 (6.69, 11.43)/7.16 (4.03, 10.28) mmHg (both: P < .001); PP decreased by 7.97 (3.05, 12.88)/5.74 (2.55,8.94) mmHg (intervention: P = .002; control: P = .001) after 8 weeks. However, the difference between the two groups was not statistically significant. Conclusion Modest salt reduction and the CM-DASH diet for hypertensive patients with type II diabetes can achieve short-term salt reduction effects. The effect on changing salt-eating habits needs to be investigated with an extended follow-up.

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适度减盐联合DASH饮食对改变高血压合并2型糖尿病患者盐饮食习惯的短期影响

【摘要】目的盐摄入过多是目前可控性慢性疾病的首要普遍危险因素。本研究评估了适度减少盐摄入量结合中国改良的高血压饮食方法(CM-DASH)饮食对2型糖尿病高血压患者钠、钾摄入量、平均动脉压(MAP)和脉压(PP)的短期影响。方法将61例患者随机分为干预组(52%低钠盐和DASH)和对照组(正常盐和DASH)。采用为期8周的饮食干预。每周记录每日盐摄入量、血压(BP)和药物使用情况。在基线、第4周和干预结束时测量24小时尿液、临时尿液和血液样本。结果59例患者(男性25例)完成了整个研究。4周后钠摄入量降低1259.66 (792.76,1726.56)/705.80 (149.21,1262.39)mg/d(干预:P < 0.001;对照:P = .015)。钾摄入量增加641.14 (73.31,1208.96)/43.43 (- 259.66,346.53)mg/d(干预:P = 0.028);MAP降低9.06 (6.69,11.43)/7.16 (4.03,10.28)mmHg(均P < 0.001);PP降低7.97 (3.05,12.88)/5.74 (2.55,8.94)mmHg(干预:P = 0.002;对照组:P = .001)。但两组间差异无统计学意义。结论高血压合并2型糖尿病患者适度减盐及CM-DASH饮食可取得短期减盐效果。改变吃盐习惯的效果需要进行长期随访研究。

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来源期刊

Clinical and Experimental Hypertension 医学-外周血管病

CiteScore

3.90

自引率

0.80%

发文量

审稿时长

6-12 weeks

期刊介绍： Clinical and Experimental Hypertension is a reputable journal that has converted to a full Open Access format starting from Volume 45 in 2023. While previous volumes are still accessible through a Pay to Read model, the journal now provides free and open access to its content. It serves as an international platform for the exchange of up-to-date scientific and clinical information concerning both human and animal hypertension. The journal publishes a wide range of articles, including full research papers, solicited and unsolicited reviews, and commentaries. Through these publications, the journal aims to enhance current understanding and support the timely detection, management, control, and prevention of hypertension-related conditions. One notable aspect of Clinical and Experimental Hypertension is its coverage of special issues that focus on the proceedings of symposia dedicated to hypertension research. This feature allows researchers and clinicians to delve deeper into the latest advancements in this field. The journal is abstracted and indexed in several renowned databases, including Pharmacoeconomics and Outcomes News (Online), Reactions Weekly (Online), CABI, EBSCOhost, Elsevier BV, International Atomic Energy Agency, and the National Library of Medicine, among others. These affiliations ensure that the journal's content receives broad visibility and facilitates its discoverability by professionals and researchers in related disciplines.