Thromboelastography in the second trimester of pregnancy in the prediction of adverse pregnancy outcome

Abstract

Thromboelastography (TEG) is a method of monitoring global homeostatic function as a dynamic process, involving the interaction between the protein coagulation cascade and platelets, as opposed to the isolated end points measured by conventional coagulation screens. The purpose of this study is to determine whether TEG variables can be used in the second trimester to predict the development of adverse pregnancy outcomes such as pre‐eclampsia and intrauterine growth restriction (IUGR defined as birth weight below the 5th centile for gestational age).