S. M. Shefin, N. Qureshi, A. Mir, Ahasnul Haq Amin, T. Ahmed, F. Afsana, Shah Alam, F. Akter, S. Emran, Tanjina Hossain, Shahjamal Khan, M. Mustari, N. Sultana, M. Saifuddin, S. Tuqan, S. Selim, S. K. Talukder, Rafiq Uddin, Feroz Amin
{"title":"Spontaneous hypoglycemia: a review","authors":"S. M. Shefin, N. Qureshi, A. Mir, Ahasnul Haq Amin, T. Ahmed, F. Afsana, Shah Alam, F. Akter, S. Emran, Tanjina Hossain, Shahjamal Khan, M. Mustari, N. Sultana, M. Saifuddin, S. Tuqan, S. Selim, S. K. Talukder, Rafiq Uddin, Feroz Amin","doi":"10.3329/IMCJMS.V13I1.42048","DOIUrl":null,"url":null,"abstract":"Spontaneous hypoglycemia is an important entity that may affect multiple organs. The differential diagnosis is broad in individuals with hypoglycemia in the absence of diabetes mellitus. Multiple etiologies may be present concurrently. Drugs, critical illnesses, hormone deficiencies, and non-islet cell tumors should be considered in those who are ill or taking medications. In apparently healthy individuals, endogenous hyperinsulinism due to insulinoma, functional β-cell disorders, or insulin autoimmune conditions are possible, as are accidental, surreptitious or factitious causes of hypoglycemia. Investigations should be guided by clinical scenario. Irrespective of the exact cause of the spontaneous hypoglycemia, treatment consists of correcting the glycemic state and preventing recurrence by alleviating underlying pathology. This review discusses the causes, diagnosis and management of spontaneous hypoglycemia. \nIMC J Med Sci 2019; 13(1): 001","PeriodicalId":55816,"journal":{"name":"IMC Journal of Medical Science","volume":"29 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IMC Journal of Medical Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3329/IMCJMS.V13I1.42048","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Spontaneous hypoglycemia is an important entity that may affect multiple organs. The differential diagnosis is broad in individuals with hypoglycemia in the absence of diabetes mellitus. Multiple etiologies may be present concurrently. Drugs, critical illnesses, hormone deficiencies, and non-islet cell tumors should be considered in those who are ill or taking medications. In apparently healthy individuals, endogenous hyperinsulinism due to insulinoma, functional β-cell disorders, or insulin autoimmune conditions are possible, as are accidental, surreptitious or factitious causes of hypoglycemia. Investigations should be guided by clinical scenario. Irrespective of the exact cause of the spontaneous hypoglycemia, treatment consists of correcting the glycemic state and preventing recurrence by alleviating underlying pathology. This review discusses the causes, diagnosis and management of spontaneous hypoglycemia.
IMC J Med Sci 2019; 13(1): 001
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