Comparative efficacy of herbal anti-diarrheal products for treatment of diarrhea in calves

Pharmaceutical and Biological Evaluations Pub Date : 2018-02-01 DOI:10.26510/2394-0859.PBE.2018.01

N. Ranaut, Pranshu Sharma, K. Ravikanth, B. Ganguly

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引用次数: 5

Abstract

Objective : The present study was undertaken to compare the efficacy of herbal drugs, Diaroak ® and Salcochek ® (M/s Ayurvet Limited), against antibiotic drugs in the treatment of calf diarrhea. Methods : 15 calves suffering from diarrhea were divided into 3 groups: T 0 ,receiving ciprofloxacin (250 mg) and tinidazole (300 mg) twice daily for three days, T 1 , receiving 15 gm Diaroak twice daily till recovery, and T 3 , receiving 15 gm Salcochektwice daily till recovery. The parameters evaluated included average number of doses required for complete recovery, total number of animals completely recovered per group, number of animals in morbid state per group, mortality recorded per group, frequency of defecation per group, presence or absence of mucus in feces along with appetite of animals, and incidence of diarrhea and mortality during post-treatment period. Results : Complete recovery was seen in all the treated animals with no recurrence. After recovery, animals treated with herbals had better consistency of feces than those treated with antibiotics. Conclusions : Herbal anti-diarrheals Diaroak and Salcocheck can be used for treating non-specific diarrhea in calves.

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中药止泻产品治疗犊牛腹泻的疗效比较

目的:比较中草药Diaroak®和Salcochek®(M/s Ayurvet Limited)治疗小牛腹泻的抗菌药物疗效。方法:15头腹泻犊牛分为3组:t0组，给予环丙沙星(250 mg)和替硝唑(300 mg)每日2次，连用3 d; t1组，给予Diaroak 15 gm，每日2次，连用3 d; t3组，给予salcochek 15 gm，每日2次，连用3 d。评估的参数包括完全恢复所需的平均剂量，每组完全恢复的动物总数，每组处于病态状态的动物数量，每组记录的死亡率，每组排便频率，粪便中是否存在粘液以及动物的食欲，以及治疗后期间腹泻的发生率和死亡率。结果:所有治疗动物均痊愈，无复发。康复后，用草药治疗的动物比用抗生素治疗的动物粪便具有更好的一致性。结论:中药止泻剂Diaroak和Salcocheck可用于犊牛非特异性腹泻的治疗。

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Pharmaceutical and Biological Evaluations

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