Biomatrices in Urethral Reconstruction

Long Zhang, Yajun Xiao
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Abstract

Urethral reconstruction is still a big challenge in urology. Traditionally, the penile skin or buccal mucosa was used as graft for replacement. However, the morbidity of the donor site was reported previously. Furthermore, there is a lack of an adequate autologous donor graft in many cases. The tissue engineered urethra may provide an alternative to the reconstruction. Herein, we reviewed the biomatrices for urethral substitution either in animal model or in clinical cases.
生物基质在尿道重建中的应用
尿道重建仍然是泌尿外科的一大挑战。传统上,阴茎皮肤或颊粘膜作为移植物进行替代。然而,供体部位的发病率以前有报道。此外,在许多病例中缺乏足够的自体供体移植物。组织工程尿道可作为尿道重建的一种替代方法。在此,我们综述了动物模型和临床病例中用于尿道替代的生物基质。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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