Advancing head and neck cancer following the coronavirus disease 2019 pandemic

W. Flynn, Raeesah Maqsood, T. Maseland, J. Montgomery, C. Douglas
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引用次数: 5

Abstract

Abstract Objective Delay in the diagnosis of head and neck cancer can result in significant excess morbidity and mortality. How the pandemic has affected patient presentation in Scotland is unknown. Method This retrospective cohort study compared all presentations of head and neck cancer between June and October of 2019 with the same period following the peak of the pandemic in 2020 in West Scotland, a region populated by 2.5 million people. Results A total of 528 patients met our inclusion criteria. Compared with 2019, patients in 2020 were more likely to present with a higher American Joint Committee on Cancer stage (odds ratio, 1.67 (95 per cent confidence interval = 1.20 to 2.31); p = 0.002), a longer preceding symptom duration (odds ratio, 2.03 (95 per cent confidence interval = 1.44 to 2.87; p < 0.001) and to have an emergency presentation (odds ratio, 2.53, (95 per cent confidence interval = 1.15 to 5.55; p = 0.017). Conclusion Patients are presenting later with more advanced head and neck cancer following the coronavirus disease 2019 pandemic.
2019冠状病毒大流行后头颈癌的进展
摘要目的头颈癌的诊断延误可导致显著的超额发病率和死亡率。目前尚不清楚大流行如何影响苏格兰患者的表现。方法:本回顾性队列研究将2019年6月至10月期间头颈癌的所有病例与2020年西苏格兰(一个人口250万的地区)大流行高峰后的同期进行了比较。结果528例患者符合纳入标准。与2019年相比,2020年的患者更有可能出现更高的美国联合委员会癌症分期(优势比,1.67(95%置信区间= 1.20至2.31);P = 0.002),前期症状持续时间较长(优势比2.03(95%可信区间= 1.44 ~ 2.87;P < 0.001)和急诊(优势比2.53,95%可信区间= 1.15至5.55;P = 0.017)。结论2019冠状病毒病大流行后,患者出现晚期头颈癌的时间较晚。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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