Identification of differentially expressed genes in adipose tissue of min pig and large white pig using RNA-seq

IF 0.8 4区农林科学 Q3 AGRICULTURE, DAIRY & ANIMAL SCIENCE

Acta Agriculturae Scandinavica Section A-Animal Science Pub Date : 2018-04-03 DOI:10.1080/09064702.2019.1611912

W. T. Wang, Dongjie Zhang, Ziguang Liu, Fugang Peng, Liang Wang, Fu Bo, Saihui Wu, Zhong-qiu Li, Zhenhua Guo, Di Liu

引用次数: 1

Abstract

ABSTRACT Min pigs and Large White pigs are two breeds that vary significantly in thickness of adipose tissue. In this study, transcriptome profiling was used to examine the fat tissues of both breeds. Min pig compared to Large White pig, 523 DEGs were down-regulated, and 112 DEGs were up-regulated. The DEGs were significantly enriched in biological process of oxidoreductase activity; helicase activity and others. In cellular component, DEGs were enriched in intracellular. In molecular function, DEGs were enriched in cytoskeletal protein binding and ion binding. Although there were many DEGs between Min pigs and Large White pigs, no significant pathway was enriched surprisingly. ATP6V0A4, TAP2, FGFBP1, PHEROA and GLYATL2 were expressed significantly higher in Large White pigs. These results suggest that the gene expression pattern in the back fat tissue was different between Large White pigs and Min pigs.

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应用RNA-seq技术鉴定小白猪和大白猪脂肪组织差异表达基因

闽猪和大白猪是脂肪组织厚度差异较大的两个品种。在这项研究中，转录组分析被用于检查这两个品种的脂肪组织。闽猪与大白猪相比，523个度下调，112个度上调。deg在氧化还原酶活性的生物过程中显著富集;解旋酶活性等。在细胞组分中，DEGs在细胞内富集。在分子功能上，DEGs富集于细胞骨架蛋白结合和离子结合。尽管闽猪和大白猪之间存在许多deg，但令人惊讶的是没有显著的途径富集。ATP6V0A4、TAP2、FGFBP1、PHEROA和GLYATL2在大白猪中表达显著升高。上述结果表明，大白猪和闽猪背部脂肪组织中基因表达谱存在差异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta Agriculturae Scandinavica Section A-Animal Science 农林科学-奶制品与动物科学

CiteScore

2.30

自引率

0.00%

发文量

审稿时长

>36 weeks

期刊介绍： Acta Agriculturæ Scandinavica, Section A – Animal Science publishes results of original research in animal science and their applications related to the following topics: -Animal breeding and genetics -Molecular genetics -Animal physiology and reproduction -Nutrition and feeding -Animal behaviour and welfare -General animal husbandry and systems of production, including economic and technical aspects -Hygiene and quality of animal products In addition to original articles, covering basic as well as applied subjects, the journal features review articles and short communications. Acta Agriculturæ Scandinavica, Section A – Animal Science forms part of a trilogy of titles published on behalf of the Nordic Association of Agricultural Scientists (NJF). The series also includes Section B - Soil & Plant Science and the recently launched Section C - Food Economics . Acta Agriculturae Scandinavica A, B and C are available to purchase as a combined subscription. This provides access to all three journals in the series, and is available to institutional subscribers only. For full pricing information, please view the Taylor & Francis Journals Price List here. Scientists in research, teaching and extension with specialised interest in animal science and production.