Prognostic Significance of the Criteria for Metastatic Involvement of Regional Lymph Nodes in Cervical Cancer According to Magnetic Resonance Imaging Findings

IF 2.2 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Radiology Research and Practice Pub Date : 2023-02-04 DOI:10.52560/2713-0118-2023-1-30-39

E. G. Zhuk, I. Kosenko

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Abstract

The objective of this study is to assess the criteria for metastatic involvement of the LN (MLN) according to magnetic resonance imaging (MRI) and to identify the most prognostically significant. The MRI data of 159 removed LN were compared with the results of a morphological study of the resected preparations. ROC- analysis (Receiver Operating Characteristic curve) was used to determine the diagnostic performance of threshold values. The test performance was evaluated depending on the area under the ROC curve — the AUC parameter (Area Under Curve). In order to evaluate the prognostic significance of MRI predictors for metastatic involvement of the LN, uni-and multivariate regression logistic analyses were performed. According to the results of multivariate analysis, the configuration index is less than or equal to 1.65, the absence of a signal from the fatty tissue of the hilum of LN, and perinodular edema are the most prognostically significant criteria for metastatic involvement of the LN (p < 0.05).

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根据磁共振成像结果判断宫颈癌区域淋巴结转移累及标准的预后意义

本研究的目的是根据磁共振成像(MRI)评估LN (MLN)转移性受累的标准，并确定最具预后意义的标准。将159例切除LN的MRI数据与切除的形态学研究结果进行比较。采用ROC分析(受试者工作特征曲线)来确定阈值的诊断性能。根据ROC曲线下的面积- AUC参数(曲线下面积)来评估测试性能。为了评估MRI预测因子对淋巴结转移累及的预后意义，进行了单因素和多因素回归逻辑分析。多因素分析结果显示，形态指数小于等于1.65，淋巴结门脂肪组织无信号，结节周围水肿是判断淋巴结转移累及的最重要预后标准(p < 0.05)。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Radiology Research and Practice RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

自引率

0.00%

发文量

审稿时长

17 weeks

期刊介绍： Radiology Research and Practice is a peer-reviewed, Open Access journal that publishes articles on all areas of medical imaging. The journal promotes evidence-based radiology practice though the publication of original research, reviews, and clinical studies for a multidisciplinary audience. Radiology Research and Practice is archived in Portico, which provides permanent archiving for electronic scholarly journals, as well as via the LOCKSS initiative. It operates a fully open access publishing model which allows open global access to its published content. This model is supported through Article Processing Charges. For more information on Article Processing charges in gen