Evaluation of the potential of human mesenchymal stem cell engrafted after in utero transplantation in murine model

Abstract

Mesenchymal stem cells derived from human placenta (hPMSc) is an important alternative source of adult stem cells. These cells with multilinear capacity represent a biological material important for regenerative medicine. In this study, we established a mouse model for in utero transplantation of hPMCs to investigate if these cells would affect long-term, organ-specific engraftment. Murine model results can be extrapolated in human medicine in the treatment of various diseases.   Key words:  Placenta, mesenchymal stem cells, engraftment, in utero transplantation.