PERBANDINGAN KADAR INTERLEUKIN 6 PADA PERSALINAN PRETERM DAN KEHAMILAN NORMAL

中国妇幼保健 Pub Date : 2022-07-16 DOI:10.32883/mchc.v1i3.961

Visti Delvina, A. Amir, E. Ermawati

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Abstract

Preterm labor occurs between 20 weeks and before 37 weeks of pregnancy. It is indicated by regular contractions of the uterus and it may cause the thinning and flattening of the cervix. Preterm labor also causes the high rates of perinatal morbidity and mortality. Increasing levels of interleukin 6 during pregnancy can stimulate the preterm labor. The design of this reseacrh was a comparative cross sectional study. It was conducted in Rasidin District Hospital, Siti Rahmah Hospital and Biomedical Laboratory, Faculty of Medicine, Andalas University, Padang on March to June 2018. There were 50 samples in this reseach. It was selected by consecutive sampling. The samples were divided into two groups: preterm labor and normal pregnancy. The interleukin 6 levels were examined by the ELISA method. Then, the data were analyzed by using the t test. The results of this reseach showed that the mean level of IL-6 in the preterm labor group was 90.22 ± 21.41ng / L. Then, 75.57 ± 14.01 ng / L for the mean level of IL-6 in the normal pregnancy group with p= 0.006. Moreover, statistical test inffered that there were significant differences between IL-6 levels in preterm labor and normal pregnancy. In short, it can be concluded that IL-6 levels in the preterm labor group were higher than normal pregnancy group.Keywords: IL-6 levels, preterm labor

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早产发生在怀孕20周到37周之前。它是指子宫有规律的收缩，它可能导致子宫颈变薄和变平。早产也导致围产期发病率和死亡率高。怀孕期间白细胞介素6水平的升高会刺激早产。本研究设计为比较横断面研究。该研究于2018年3月至6月在巴东安达拉斯大学医学院拉西丁地区医院、西蒂拉赫玛医院和生物医学实验室进行。这项研究有50个样本。它是通过连续抽样选择的。样本分为两组:早产和正常妊娠。ELISA法检测白细胞介素6水平。然后采用t检验对数据进行分析。本研究结果显示，早产组IL-6平均水平为90.22±21.41ng / L，正常妊娠组IL-6平均水平为75.57±14.01 ng / L, p= 0.006。此外，统计检验推断，IL-6水平在早产和正常妊娠有显著差异。总之，可以得出结论，早产组IL-6水平高于正常妊娠组。关键词:IL-6水平;早产

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来源期刊

中国妇幼保健

自引率

0.00%

发文量

45761

期刊介绍： Maternal and Child Health Care of China is a semi-monthly journal sponsored by the Chinese Preventive Medicine Association and Jilin Medical Journal Press, with an impact factor. The journal covers multiple columns, including reform and management, health education, women's health, children's health, etc. Maternal and Child Health Care of China is not only one of China's authoritative academic journals, but also included in the RCCSE China Authoritative Academic Journals (A+) and China Academic Journal Impact Factor Annual Report Q1 Zone Journals. In addition, it is also fully included in the China Core Journals (Selection) Database and China Journal Full-text Database (CJFD).