The Effect of Obesity on the Time to Recurrence in Ovarian Cancer: A Retrospective Study

Clinical Ovarian and Other Gynecologic Cancer Pub Date : 2013-12-01 DOI:10.1016/j.cogc.2014.02.002

Karina E. Hew , Arvind Bakhru , Evan Harrison , Mehmet O. Turan , Ryan MacDonald , Dwight D. Im , Neil B. Rosenshein

{"title":"The Effect of Obesity on the Time to Recurrence in Ovarian Cancer: A Retrospective Study","authors":"Karina E. Hew , Arvind Bakhru , Evan Harrison , Mehmet O. Turan , Ryan MacDonald , Dwight D. Im , Neil B. Rosenshein","doi":"10.1016/j.cogc.2014.02.002","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction/Background</h3><p>The objective of this study was to examine whether obesity affects the time to recurrence in primary epithelial ovarian cancer.</p></div><div><h3>Patients and Methods</h3><p>A multicenter retrospective chart review was performed between 2004 and 2009. Three hundred seventy patients were eligible for analysis. Demographic and clinicopathological variables and treatment-related data were collected. Women with a body mass index (BMI) > 30 were categorized as obese. The time to recurrence was quantified in terms of months. Survival analyses were performed using the Kaplan-Meier method and compared using log-rank testing.</p></div><div><h3>Results</h3><p>One hundred thirty (35%) obese patients were compared with 240 (65%) nonobese patients. A recurrence was documented in 125 (47.9%) nonobese patients and 49 (37.7%) obese patients. Time to recurrence between both BMI groups was identical, at 15 months (<em>P</em> = 1.0). The progression-free survival was similar in obese and nonobese subjects (<em>P</em> = .118).</p></div><div><h3>Conclusion</h3><p>Obesity does not affect the recurrence time in patients with primary ovarian cancer.</p></div>","PeriodicalId":100274,"journal":{"name":"Clinical Ovarian and Other Gynecologic Cancer","volume":"6 1","pages":"Pages 31-35"},"PeriodicalIF":0.0000,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cogc.2014.02.002","citationCount":"5","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Ovarian and Other Gynecologic Cancer","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2212955314000246","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 5

Abstract

Introduction/Background

The objective of this study was to examine whether obesity affects the time to recurrence in primary epithelial ovarian cancer.

Patients and Methods

A multicenter retrospective chart review was performed between 2004 and 2009. Three hundred seventy patients were eligible for analysis. Demographic and clinicopathological variables and treatment-related data were collected. Women with a body mass index (BMI) > 30 were categorized as obese. The time to recurrence was quantified in terms of months. Survival analyses were performed using the Kaplan-Meier method and compared using log-rank testing.

Results

One hundred thirty (35%) obese patients were compared with 240 (65%) nonobese patients. A recurrence was documented in 125 (47.9%) nonobese patients and 49 (37.7%) obese patients. Time to recurrence between both BMI groups was identical, at 15 months (P = 1.0). The progression-free survival was similar in obese and nonobese subjects (P = .118).

Conclusion

Obesity does not affect the recurrence time in patients with primary ovarian cancer.

查看原文本刊更多论文

肥胖对卵巢癌复发时间影响的回顾性研究

本研究的目的是探讨肥胖是否会影响原发性上皮性卵巢癌的复发时间。患者和方法2004 - 2009年进行多中心回顾性图表分析。370名患者符合分析条件。收集人口统计学和临床病理变量以及治疗相关数据。有身体质量指数(BMI)的女性;30人被归类为肥胖。复发时间以月为单位量化。生存分析采用Kaplan-Meier法，比较采用log-rank检验。结果肥胖患者130例(35%)，非肥胖患者240例(65%)。125例(47.9%)非肥胖患者和49例(37.7%)肥胖患者复发。两个BMI组的复发时间相同，均为15个月(P = 1.0)。肥胖和非肥胖受试者的无进展生存期相似(P = 0.118)。结论肥胖对原发性卵巢癌患者的复发时间无影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Clinical Ovarian and Other Gynecologic Cancer

自引率

0.00%

发文量