INTERACTION BETWEEN Clq, Clr and Cls FROM HUMAN SERUM

A. Laurell, U. Mårtensson
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Abstract

The presence of Ca++ changed the electrophoretic mobility of CIs. Incubation of purified preparations of Clr and CIs in the presence of Ca++ resulted in the formation of a Clr–CIs complex, which by crossed immunoelectrophoresis was demonstrated in the β-region. In mixtures of purified Clq, Clr and CIs containing Ca++ a complex consisting of Clq, r, s was obtained, which crossed immunoelectrophoresis demonstrated in the γ-region. No complex formation was found between Clq and CIs in the absence of Clr.
Clq、Clr与人血清中Cls的相互作用
ca++的存在改变了CIs的电泳迁移率。Clr和CIs纯化物在ca++存在下孵育可形成Clr - CIs复合物,通过交叉免疫电泳在β区证实了这一点。在含有ca++的纯化Clq、Clr和CIs的混合物中,得到了一个由Clq、r、s组成的络合物,其交叉免疫电泳显示在γ区。在没有Clr的情况下,Clq和CIs之间没有形成络合物。
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