Effects of pre and postnatal 2450 MHz continuous wave (CW) radiofrequency radiation on thymus: Four generation exposure

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2022-05-30 DOI:10.1080/15368378.2022.2079673

Fazile Cantürk Tan, B. Yalçın, A. Yay, B. Tan, K. Yeğin, S. Dasdag

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引用次数: 2

Abstract

ABSTRACT This study aims to investigate the effects of pre- and postnatal 2450 MHz continuous wave (CW) radiofrequency radiation (RFR) on the thymus of rats spanning four generations. Four groups; sham, irradiated female, irradiated male, irradiated male and female, each consisting of four rats (one male and three females), were created. During the experiment, rats in the exposure groups were whole-body exposed to 2450 MHz CW-RFR for 12 h/day. Irradiation started one month before the fertilization in the experimental group. When the offspring were two months old, four rats, one male and three female, were allocated for the second-generation study. The remaining offspring were sacrificed under general anesthesia, and their thymuses were removed. The same procedure was applied to the next generation. Two months after the second generation gave birth, third-generation rats were decapitated, and their thymuses were removed. In all groups, cortex, medulla and resident cells could be clearly distinguished in the second and third generations. No differences were observed between the control and two experimental groups, defined as irradiated female and irradiated male. In contrast, vascularization was observed in the thymus of the fourth-generation offspring of the group where both males and females were irradiated. The number of offspring and mass of all rats decreased in the third-generation group. Pre-and postnatal 2450 MHz continuous wave radiofrequency radiation exposure may potentially affect the thymus of future generations.

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产前和产后2450mhz连续波(CW)射频辐射对胸腺的影响:四代暴露

摘要本研究旨在探讨2450 MHz连续波(CW)射频辐射(RFR)对四代大鼠胸腺的影响。四组;造出假大鼠、受辐射的雌性大鼠、受辐射的雄性大鼠、受辐射的雄性大鼠和雌性大鼠，每只由四只大鼠组成(一只雄性和三只雌性)。实验期间，暴露组大鼠全身暴露于2450 MHz CW-RFR，持续12小时/天。实验组在受精前1个月开始照射。当后代两个月大的时候，四只老鼠，一公三母，被分配到第二代研究中。其余幼鼠在全身麻醉下处死，切除胸腺。同样的程序也适用于下一代。第二代分娩两个月后，第三代大鼠被斩首，胸腺被切除。在所有组中，皮层、髓质和常驻细胞在第二代和第三代都可以明显区分。对照组和两个实验组之间没有观察到差异，定义为受辐照的女性和受辐照的男性。相比之下，在雄性和雌性都受到辐射的第四代后代的胸腺中观察到血管化。第三代组大鼠子代数和质量均下降。产前和产后2450兆赫连续波射频辐射暴露可能会影响后代的胸腺。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.