Chemical Constituents from the Leaves of Mahonia japonica

Abstract

The chemical constituents of the leaves of Mahonia japonica were investigated by column chromatography. We isolated eight flavonoids, including quercetin (1), quercetin 3-O-β-D-glucopyranoside (2), quercetin 3-O-β-D-galactopyranoside (3), quercetin 3-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside (4), isorhamnetin (5), isorhamnetin 3-O-β-D-glucopyranoside (6), isorhamnetin 3-O-β-D-galactopyranoside (7), and isorhamnetin 3-O-β-D-glucopyranosl-(1→6)-β-D-glucopyranoside (8), and four phenollic carboxylic acids, in cluding caffeic acid (9),p-hydroxy-benzoic acid (10), protocatechuic acid (11), and vanillic acid (12) from the n-BuOH soluble fraction of the methanolic extract. The structures of these com pounds were established by spectroscopic and chemical analysis.