Recent Advance of Neuronal Cell Antigens and Autoimmune Encephalitis

Abstract

Patients with autoimmune encephalitis rarely present to neurology clinic before presenting to memory, seizure, movement disorder, and psychiatry clinics, recent discovery of neuronal surface autoantibodies have shifted the balance towards the diagnosis of autoimmune encephalitis, patients with autoimmune encephalitis used to receive the diagnosis of infectious encephalitis, with poor response to antiseizure, antibacterial and antiviral therapy, autoimmune encephalitis has a fundamental phenotype which is very specific even if serology was negative, early diagnosis is of paramount importance due to starting immunotherapy and avoid mortality and significant morbidity.