Wound healing in compound fractures with significant tissue loss: Treated with platelet-rich fibrin dressing - prospective study

Dr. Suriyan Sugavanam, Dr. Shankarlal
{"title":"Wound healing in compound fractures with significant tissue loss: Treated with platelet-rich fibrin dressing - prospective study","authors":"Dr. Suriyan Sugavanam, Dr. Shankarlal","doi":"10.22271/ortho.2023.v9.i2e.3387","DOIUrl":null,"url":null,"abstract":"Introduction: Platelet-rich fibrin (PRF) naturally derived second generation of platelet concentrates, which has gained increasing awareness in recent years for regenerative procedures. This biologic additive is completely autologous, easy to prepare, has minimal expense, and possesses prolonged growth factor release, together with several other advantages over traditionally prepared platelet concentrates. However, reference data about potential effect of some PRF components on hard and soft tissue healing are still conflicting. The current article intends to clarify the relevant advances about physiological role of certain PRF components on wound healing in 50 patients. In this study shows effective wound healing in limited duration with p value of < 0.005. Conclusion: PRF has more regenerative progression than other platelet concentrators easily available, affordable and inexpensive for wound healing in minimal duration.","PeriodicalId":14302,"journal":{"name":"International Journal of Orthopaedics Sciences","volume":"119 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Orthopaedics Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22271/ortho.2023.v9.i2e.3387","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Introduction: Platelet-rich fibrin (PRF) naturally derived second generation of platelet concentrates, which has gained increasing awareness in recent years for regenerative procedures. This biologic additive is completely autologous, easy to prepare, has minimal expense, and possesses prolonged growth factor release, together with several other advantages over traditionally prepared platelet concentrates. However, reference data about potential effect of some PRF components on hard and soft tissue healing are still conflicting. The current article intends to clarify the relevant advances about physiological role of certain PRF components on wound healing in 50 patients. In this study shows effective wound healing in limited duration with p value of < 0.005. Conclusion: PRF has more regenerative progression than other platelet concentrators easily available, affordable and inexpensive for wound healing in minimal duration.
具有明显组织丢失的复合骨折的伤口愈合:用富血小板纤维蛋白敷料治疗-前瞻性研究
富血小板纤维蛋白(PRF)天然衍生的第二代血小板浓缩物,近年来在再生过程中获得了越来越多的认识。这种生物添加剂是完全自体的,易于制备,成本最低,并且具有长时间的生长因子释放,以及与传统制备的血小板浓缩物相比的其他几个优点。然而,关于某些PRF成分对软硬组织愈合的潜在影响的参考数据仍然存在冲突。本文拟对50例患者中PRF成分在创面愈合中的生理作用的相关进展进行综述。本研究显示伤口在有限时间内有效愈合,p值< 0.005。结论:PRF比其他血小板浓缩剂具有更强的再生进展,可在短时间内实现伤口愈合。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信