M. Marino, Adrian Chiow Kah Heng, G. Vaccarella, O. Potapov, Andrzej Lech Komorowski
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引用次数: 0
Abstract
Backgrounds: Several anastomoses have been described for the reconstruction of the pancreatic stump after pancreaticoduodenectomy. No technique showed a superiority over the others in terms of post-operative pancreatic fistula formation (POPF) in open neither during a minimally invasive approach. Methods: We compared the surgical outcomes of fourteen patients classified as high-risk for POPF who underwent a Blumgart anastomosis (BA) with that of patients who underwent a Cattell-Warren (CW). A 1:1 case-matched analysis was performed according to the variables of the risk score for post-operative pancreatic fistula (POPF) formation. Results: The overall operative time was similar (373±115 vs 398±127 min, p=0.567) while fashioning of the CW anastomosis required a longer time (38±21 vs 29±10, p<0.05). The overall morbidity rate was comparable among the two groups (p=0.273), while the incidence of clinically relevant-POPF was lower in the BA group (0 vs 3, p<0.05). No differences were observed in reoperation rate (p=0.445) and in postoperative length of stay (11.5 vs 12.6, p=0.367). Conclusion: The BA anastomosis is a potential alternative to the CW technique in a high-risk population for POPF formation. It shows benefits in terms of shorter anastomotic time and lower rate of clinically relevant-POPF.
背景:几种吻合方式用于胰十二指肠切除术后胰残端重建。在开放性和微创入路手术后胰瘘形成(POPF)方面,没有一种技术比其他技术优越。方法:我们比较了14例高危POPF患者行Blumgart吻合(BA)和行cattel - warren吻合(CW)的手术结果。根据术后胰瘘(POPF)形成风险评分变量进行1:1病例匹配分析。结果:两组总手术时间相近(373±115 min vs 398±127 min, p=0.567),但CW吻合口形成时间较长(38±21 min vs 29±10 min, p<0.05)。两组总发病率相当(p=0.273),而BA组临床相关- popf发生率较低(0 vs 3, p<0.05)。再手术率(p=0.445)和术后住院时间(11.5 vs 12.6, p=0.367)差异无统计学意义。结论:在POPF形成的高危人群中,BA吻合术是一种潜在的替代CW技术。它在缩短吻合时间和降低临床相关- popf率方面显示出益处。
期刊介绍:
Starting with this issue "Annals of Fundeni Hospital", founded in 1996 as the scientific journal of the prestigious hospital Fundeni becomes "Journal of Translational Medicine and Research" (JTMR), an Journal of the Academy of Medical Sciences of Romania. Therefore, an 18 years old Journal, attested and indexed in Elsevier Bibliographic Databases, Amsterdam and also indexed in SCOPUS, is continuing a tradition of excellence that lasted almost two decades. The new title of the Journal is inspired first of all from the important developments of translational research In Fundeni Clinical Institute and the "C.C Iliescu Institute for Cardio-Vascular Diseases", in parallel with the national and international trend to promote and develop this important area or medical research. Although devoted mainly to translational research, JTMR will continue to promote both basic and clinical research.